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Cat. No.: HY-42484S

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ER-076349-d₃

Name: ER-076349-d3
Brand: MedChemExpress
SKU: HY-42484S
Availability: PreOrder

(Synonyms: Eribulin intermediate-d₃)

ER-076349-d₃ (Eribulin intermediate-d₃) is the deuterated-labeled ER-076349 (HY-42484). ER-076349 (Eribulin intermediate) is an inhibitor of tubulin polymerization, induces G2-M cell cycle arrest, and disrupts mitotic spindles. ER-076349 inhibits cancer cell growth, and inhibits tumor growth in several human tumor xenografts. ER-076349 is an analog of Halichondrin B.

For research use only. We do not sell to patients.

Formula: C₄₀H₅₅D₃O₁₂
Molecular Weight:733.90

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

ER-076349-d₃ Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
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Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 253128-15-3
Molecular Weight 733.90
Formula C₄₀H₅₅D₃O₁₂
SMILES

C[C@@H](C1=C)C[C@@H](O[C@@H]1C[C@@H]2O[C@H](C[C@H](O)CO)[C@H](OC([2H])([2H])[2H])[C@H]2CC3=O)CC[C@@H]4O[C@@H](CC[C@@]56C[C@]7([H])[C@H](O6)[C@H]8[C@@H](O7)[C@@H](O5)[C@@]9([H])O[C@@H](C3)CC[C@]9([H])O8)CC4=C
Synonyms

Eribulin intermediate-d₃
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.