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Results for "

dystonia

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Cholinesterase (ChE) (3) Endogenous Metabolite (1) Isotope-Labeled Compounds (1) KMO (2) mAChR (6) nAChR (1) Reference Standards (4)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Neurological Disease (12)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12347

Ro 61-8048 5 Publications Verification	KMO	Neurological Disease
Ro 61-8048 is an orally active and selective inhibitor of kynurenine 3-hydroxylase, with an IC₅₀ of 37 nM. Ro 61-8048 provokes a significant increase of extracellular kynurenic acid concentrations .

HY-B1277

Trihexyphenidyl hydrochloride 3 Publications Verification	mAChR Cholinesterase (ChE)	Neurological Disease
Trihexyphenidyl hydrochloride is a selective and orally active M₁ muscarinic receptor antagonist with an IC₅₀ of 3.7 nM for rat cerebral cortex M1 muscarinic receptors. Trihexyphenidyl hydrochloride modulates cholinergic activity, countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl hydrochloride improves movement disorder, inhibits McN-A-343 (HY-107648)-induced pressor responses, vagally-induced bradycardia and vasodilatation. Trihexyphenidyl hydrochloride can be used for the research of Parkinson's disease. .

HY-B1139

Tolperisone hydrochloride 2 Publications Verification	Apoptosis	Neurological Disease
Tolperisone hydrochloride is a centrally acting muscle relaxant studied in neurological disorders causing pathological rhabdomyosclerosis (pyramidal tract injury, multiple sclerosis, myelopathy, encephalomyelitis), spastic paralysis, and other muscle dystonia-related Encephalopathy. Tolperisone hydrochloride also has antiviral activity .

HY-108234

VU 0255035 1 Publications Verification VU 255035	mAChR	Neurological Disease
VU0255035 is a highly selective and competitive M1 mAChR antagonist. VU0255035 blocks M1 mAChR signals to reduce epileptic seizures and regulate neuronal membrane potential. VU0255035 can be used in research related to central nervous system diseases, such as epilepsy, Parkinson's disease, and dystonia .

HY-B1277A

Trihexyphenidyl	mAChR Cholinesterase (ChE)	Cardiovascular Disease Neurological Disease
Trihexyphenidyl is a selective and orally active M₁ muscarinic receptor antagonist with an IC₅₀ of 3.7 nM for rat cerebral cortex M1 muscarinic receptors. Trihexyphenidyl modulates cholinergic activity, countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl improves movement disorder, inhibits McN-A-343 (HY-107648)-induced pressor responses, vagally-induced bradycardia and vasodilatation. Trihexyphenidyl can be used for the research of Parkinson's disease. .

HY-18159

TC-6683 AZD1446	nAChR	Neurological Disease
TC-6683 (AZD1446) is a selective α4β2 nicotinic acetylcholine receptor (nAChR) agonist. TC-6683 does not show significant therapeutic effects in the animal model of DYT1 dystonia.TC-6683 can be used for the research of neurological disease, such as cognitive disorder .

HY-12347R

Ro 61-8048 (Standard)	KMO	Neurological Disease
Ro 61-8048 (Standard) is the analytical standard of Ro 61-8048. This product is intended for research and analytical applications. Ro 61-8048 is an orally active and selective inhibitor of kynurenine 3-hydroxylase, with an IC50 of 37 nM. Ro 61-8048 provokes a significant increase of extracellular kynurenic acid concentrations .

HY-B1139R

Tolperisone hydrochloride (Standard)	Reference Standards Apoptosis	Neurological Disease
Tolperisone (hydrochloride) (Standard) is the analytical standard of Tolperisone (hydrochloride). This product is intended for research and analytical applications. Tolperisone hydrochloride is a centrally acting muscle relaxant studied in neurological disorders causing pathological rhabdomyosclerosis (pyramidal tract injury, multiple sclerosis, myelopathy, encephalomyelitis), spastic paralysis, and other muscle dystonia-related Encephalopathy. Tolperisone hydrochloride also has antiviral activity .

HY-B1277R

Trihexyphenidyl hydrochloride (Standard)	Reference Standards mAChR Cholinesterase (ChE)	Neurological Disease
Trihexyphenidyl hydrochloride (Standard) is the analytical standard of Trihexyphenidyl hydrochloride (HY-B1277). This product is intended for research and analytical applications. Trihexyphenidyl is a selective and orally active M₁ muscarinic receptor antagonist with an IC₅₀ of 3.7 nM for rat cerebral cortex M1 muscarinic receptors. Trihexyphenidyl modulates cholinergic activity, countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl improves movement disorder, inhibits McN-A-343 (HY-107648)-induced pressor responses, vagally-induced bradycardia and vasodilatation. Trihexyphenidyl can be used for the research of Parkinson's disease. .

HY-182384

VU6015241	mAChR	Neurological Disease
VU6015241 is a selective, blood-brain barrier-permeable M4 mAChR Antagonist with a K_i value of 43.3 nM. VU6015241 is used for the research of dystonia and related movement disorders .

HY-113057R

3-Hydroxycapric acid (Standard)	Reference Standards Endogenous Metabolite	Cancer
Trihexyphenidyl (hydrochloride) (Standard) is the analytical standard of Trihexyphenidyl (hydrochloride). This product is intended for research and analytical applications. Trihexyphenidyl hydrochloride is a potent and selective M1 muscarinic receptor antagonist. Trihexyphenidyl hydrochloride shows anticholinergic activity, and can be used for Parkinson syndrome or dystonia research .

HY-B1139S

Tolperisone-d10 hydrochloride	Isotope-Labeled Compounds	Neurological Disease
Tolperisone-d₁₀ (hydrochloride) is the deuterium labeled Tolperisone hydrochloride. Tolperisone hydrochloride is a centrally acting muscle relaxant, is indicated for use in the treatment of pathologically increased tone of the cross-striated muscle caused by neurological diseases (damage of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis) and of spastic paralysis and other encephalopathies manifested with muscular dystonia.

HY-108234R

VU 0255035 (Standard) VU 255035 (Standard)	Reference Standards mAChR	Neurological Disease
VU 0255035 (Standard) is the analytical standard of VU 0255035 (HY-108234). This product is intended for research and analytical applications. VU0255035 is a highly selective and competitive M1 mAChR antagonist. VU0255035 blocks M1 mAChR signals to reduce epileptic seizures and regulate neuronal membrane potential. VU0255035 can be used in research related to central nervous system diseases, such as epilepsy, ParK_inson's disease, and dystonia .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113057R

3-Hydroxycapric acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Trihexyphenidyl (hydrochloride) (Standard) is the analytical standard of Trihexyphenidyl (hydrochloride). This product is intended for research and analytical applications. Trihexyphenidyl hydrochloride is a potent and selective M1 muscarinic receptor antagonist. Trihexyphenidyl hydrochloride shows anticholinergic activity, and can be used for Parkinson syndrome or dystonia research .

Species:	Human (2) Mouse (2)
Tag:	His (4)
Source:	P. pastoris (1) Sf9 insect cells (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P73564

	Tyrosine Hydroxylase Protein, Human (sf9, His) DYT14; TH; TYH dystonia 14; TYH; Tyrosine 3-monooxygenase	Human	Sf9 insect cells
	Tyrosine hydroxylase is a key enzyme in the biosynthesis of catecholamines, catalyzing the conversion of L-tyrosine into L-dopa, which is the rate-limiting step in the synthesis of dopamine, norepinephrine, and epinephrine. Tyrosine is hydroxylated using tetrahydrobiopterin and oxygen. Tyrosine Hydroxylase Protein, Human (sf9, His) is the recombinant human-derived Tyrosine Hydroxylase protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P73563A

	Tyrosine Hydroxylase Protein, Mouse (sf9, His) DYT14; TH; TYH dystonia 14; TYH; Tyrosine 3-monooxygenase	Mouse	Sf9 insect cells
	Tyrosine hydroxylase protein is a key catalyst in the biosynthesis of catecholamines, including dopamine, norepinephrine, and epinephrine, and oversees the conversion of L-tyrosine to L-dihydroxyphenylalanine (L-Dopa) , which is the critical and rate-limiting step pathway in synthesis.Tyrosine Hydroxylase Protein, Mouse (sf9, His) is the recombinant mouse-derived Tyrosine Hydroxylase protein, expressed by sf9 insect cells , with N-His labeled tag.

HY-P73563

	Tyrosine Hydroxylase Protein, Mouse (sf9, His, solution) DYT14; TH; TYH dystonia 14; TYH; Tyrosine 3-monooxygenase	Mouse	Sf9 insect cells
	Tyrosine hydroxylase protein is a key catalyst in the biosynthesis of catecholamines, including dopamine, norepinephrine, and epinephrine, and oversees the conversion of L-tyrosine to L-dihydroxyphenylalanine (L-Dopa) , which is the critical and rate-limiting step pathway in synthesis.Tyrosine Hydroxylase Protein, Mouse (sf9, His) is the recombinant mouse-derived Tyrosine Hydroxylase protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P71840

	DST Protein, Human (P.pastoris, His) DST; BPAG1; DMH; DT; dystonia musculorum protein; Hemidesmosomal plaque protein	Human	P. pastoris
	DST proteins integrate intermediate filaments, actin, and microtubule networks. DST Protein, Human (P.pastoris, His) is the recombinant human-derived DST protein, expressed by P. pastoris , with N-His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-B1139S

Tolperisone-d10 hydrochloride
Tolperisone-d₁₀ (hydrochloride) is the deuterium labeled Tolperisone hydrochloride. Tolperisone hydrochloride is a centrally acting muscle relaxant, is indicated for use in the treatment of pathologically increased tone of the cross-striated muscle caused by neurological diseases (damage of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis) and of spastic paralysis and other encephalopathies manifested with muscular dystonia.

Tolperisone-d10 hydrochloride

Tolperisone-d₁₀ (hydrochloride) is the deuterium labeled Tolperisone hydrochloride. Tolperisone hydrochloride is a centrally acting muscle relaxant, is indicated for use in the treatment of pathologically increased tone of the cross-striated muscle caused by neurological diseases (damage of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis) and of spastic paralysis and other encephalopathies manifested with muscular dystonia.

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (2) Mouse (2)
Application:	IHC-P (1) ICC/IF (1) IF-Tissue (1) WB (2) FC (1)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87216

	GCH1 Antibody (YA6904) dystonia 14 antibody	WB, IHC-P, ICC/IF, FC, IF-Tissue	Human, Mouse, Rat
	GCH1 Antibody (YA6904) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GCH1.

HY-P810356

	Torsin 1A Antibody (YA9678) DQ2, dystonia 1, dystonia 1 protein, dystonia 1 torsion, Dyt1, TOR1A, TOR1A_HUMAN, Torsin 1A, Torsin A, Torsin family 1 member A	WB	Human, Mouse, Rat
	Torsin 1A Antibody (YA9678) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Torsin 1A.

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