199666-03-0
199666-03-0
Chemical Structure
Ro 61-8048
- CAS No.: 199666-03-0
- Formula:C17H15N3O6S2
- Molecular Weight:421.45
IUPAC Name: 3,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonamide
InChIKey: NDPBMCKQJOZAQX-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(OC)C(OC)=C1)(NC2=NC(C3=CC=CC([N+]([O-])=O)=C3)=CS2)=O
Biological Activity: Ro 61-8048 is an orally active and selective inhibitor of kynurenine 3-hydroxylase, with an IC50 of 37 nM. Ro 61-8048 provokes a significant increase of extracellular kynurenic acid concentrations[1].
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Ro 61-8048 | 99.93% | Ro 61-8048 is an orally active and selective inhibitor of kynurenine 3-hydroxylase, with an IC50 of 37 nM. Ro 61-8048 provokes a significant increase of extracellular kynurenic acid concentrations. | ||||||||||||||||||||
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Ro 61-8048 (Standard) | ≥98% | Ro 61-8048 (Standard) is the analytical standard of Ro 61-8048. This product is intended for research and analytical applications. Ro 61-8048 is an orally active and selective inhibitor of kynurenine 3-hydroxylase, with an IC50 of 37 nM. Ro 61-8048 provokes a significant increase of extracellular kynurenic acid concentrations. | ||||||||||||||||||||
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