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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
76 Results for "
efflux+pump
" in MedChemExpress (MCE) Product Catalog:
Products (76)
76 Results for "efflux+pump" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: MC-207,110 dihydrochloride; Phe-Arg-β-naphthylamide dihydrochloride
5
Category:
Infection Flavonoids Flavones Plants Compositae Disease Research Fields Genista maderensis (Webb & Berthel.) Lowe Inflammation/Immunology
Target:
4
4
Category:
4
4 Cited Publications
Art. -Nr.: HY-N1423B
CAS. Nr.: 1192657-83-2
1
1 Cited Publications
Art. -Nr.: HY-17390A
CAS. Nr.: 27833-64-3
Target:
Forschungsgebiete:
Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages .
Art. -Nr.: HY-N1423S
CAS. Nr.: 1201918-15-1
Art. -Nr.: HY-D0180
CAS. Nr.: 17455-13-9
Synonyms: 18C6; 1,4,7,10,13,16-Hexaoxacyclooctadecane
Art. -Nr.: HY-124819
CAS. Nr.: 957471-96-4
D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively . D13-9001 exhibits antibiotic activities .
Target:
Forschungsgebiete:
2-Phenylacetophenone has broad-spectrum efflux pump inhibition activity. 2-Phenylacetophenone is a benzoin derivative used as a photoinitiator in vinyl polymerization .
Art. -Nr.: HY-N2947
CAS. Nr.: 114567-34-9
Category:
Natural Products other families Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
Target:
Art. -Nr.: HY-P5589
CAS. Nr.: 131463-18-8
Synonyms: PlnA
Forschungsgebiete:
Art. -Nr.: HY-W013105
CAS. Nr.: 338950-81-5
Synonyms: N-Cholylglycine sodium salt, 98%
Art. -Nr.: HY-145301
CAS. Nr.: 65840-95-1
Mycobactin-IN-1, a pyrazoline analogue, is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-1 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway. Mycobactin-IN-1 inhibits whole-cell drug efflux pumps in M. smegmatis. Mycobactin-IN-1 eradicates intracellularly surviving mycobacteria. Mycobactin-IN-1 shows an excellent in vivo pharmacokinetic profile. Mycobactin-IN-1 can be used for the research of tuberculosis .
Category:
BDM91270 (compound 29) is an E. coli AcrAB-TolC efflux pump inhibitor with an EC90 of 0.6 μM for wild-type E. coli AcrB. BDM91270 can be used in the study of Escherichia coli drug resistance .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
