Search Result

Results for "

erythrocyte AChE

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Carboxylesterase (CES) (1) Cholinesterase (ChE) (11) Drug Metabolite (1) Isotope-Labeled Compounds (2) Reference Standards (2)
By Research Areas:	Cancer (1) Inflammation/Immunology (3) Neurological Disease (8)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: nAChR mAChR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0882

Edrophonium chloride	Cholinesterase (ChE)	Neurological Disease Inflammation/Immunology
Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has K_i values of 0.2, 0.2, and 0.4 μM and IC₅₀ values of 0.2, 0.05, and 0.5 μM for *AChE* in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis .

HY-W016188

1-Naphthyl acetate	Cholinesterase (ChE)	Others
1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning .

HY-W130236

Methylene Violet 3RAX	Cholinesterase (ChE)	Cancer
Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an K_is of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy) .

HY-110389

Pitofenone hydrochloride	Cholinesterase (ChE)	Neurological Disease
Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with K_is of 36 and 45 μM, respectively .

HY-134137

Donepezil N-oxide	Cholinesterase (ChE) Drug Metabolite	Neurological Disease
Donepezil N-oxide, a metabolite of Donepezil (HY-14566), is human erythrocyte acetylcholinesterase (AChE) inhibitor .

HY-W016188R

1-Naphthyl acetate (Standard)	Reference Standards Cholinesterase (ChE)	Others
1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning .

HY-B0882S

Edrophonium-d5 chloride	Isotope-Labeled Compounds Cholinesterase (ChE)	Neurological Disease Inflammation/Immunology
Edrophonium-d₅ chloride is the deuterium labeled Edrophonium chloride (HY-B0882). Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has K_i values of 0.2, 0.2, and 0.4 μM and IC₅₀ values of 0.2, 0.05, and 0.5 μM for *AChE* in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis .

HY-105853

Pitofenone	Cholinesterase (ChE)	Neurological Disease
Pitofenone, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with K_is of 36 and 45 μM, respectively .

HY-105853S

Pitofenone-d4	Isotope-Labeled Compounds	Neurological Disease
Pitofenone-d₄ is deuterium labeled Pitofenone (HY-105853). Pitofenone, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with K_is of 36 and 45 μM, respectively .

HY-B0882R

Edrophonium chloride (Standard)	Reference Standards Cholinesterase (ChE)	Neurological Disease Inflammation/Immunology
Edrophonium chloride (Standard) is the analytical standard of Edrophonium chloride (HY-B0882). This product is intended for research and analytical applications. Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has K_i values of 0.2, 0.2, and 0.4 μM and IC₅₀ values of 0.2, 0.05, and 0.5 μM for *AChE* in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis.

HY-N16715

Monardic acid A	Cholinesterase (ChE)	Neurological Disease
Monardic acid A is a selective inhibitor of *AChE, with an IC₅₀* of 53.1 μM against AChE from electric eel. Monardic acid A shows weak inhibitory activity against human erythrocyte AChE (IC₅₀ >100 μM) and has no significant inhibitory effect on BChE. Monardic acid A reduces acetylcholine breakdown by inhibiting AChE activity, and also exhibits inhibitory activity against histamine release and hyaluronidase, thus exerting anti-inflammatory and neurotransmitter regulatory effects. Monardic acid A can be isolated from lungwort (Pulmonaria officinalis) and thyme (Thymus gobicus), and is mainly used in the development of anti-inflammatory drugs and drugs related to neurodegenerative diseases .

HY-120042

Heptenophos	Carboxylesterase (CES) Cholinesterase (ChE)	Others
Heptenophos is an inhibitor of AChE and plasma carboxylesterase (CES). By inhibiting AChE activity, Heptenophos causes the accumulation of acetylcholine at cholinergic synapses, thereby triggering typical symptoms of organophosphate poisoning. Heptenophos exhibits rapid lethal toxicity in male albino mice, but its toxic effects are effectively antagonized by obidoxime, and Memantine (HY-B0591) further enhances the detoxification efficacy of obidoxime. Therefore, Heptenophos is commonly used in studies related to the mechanism of organophosphate poisoning and detoxification strategies .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16715

Monardic acid A	Structural Classification Lignans Phenylpropanoids Plants Pulmonaria officinalis L. Boraginaceae Source Classification	Cholinesterase (ChE)
Monardic acid A is a selective inhibitor of *AChE, with an IC₅₀* of 53.1 μM against AChE from electric eel. Monardic acid A shows weak inhibitory activity against human erythrocyte AChE (IC₅₀ >100 μM) and has no significant inhibitory effect on BChE. Monardic acid A reduces acetylcholine breakdown by inhibiting AChE activity, and also exhibits inhibitory activity against histamine release and hyaluronidase, thus exerting anti-inflammatory and neurotransmitter regulatory effects. Monardic acid A can be isolated from lungwort (Pulmonaria officinalis) and thyme (Thymus gobicus), and is mainly used in the development of anti-inflammatory drugs and drugs related to neurodegenerative diseases .

Cat. No.	Product Name	Chemical Structure

HY-B0882S

Edrophonium-d5 chloride
Edrophonium-d₅ chloride is the deuterium labeled Edrophonium chloride (HY-B0882). Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has K_i values of 0.2, 0.2, and 0.4 μM and IC₅₀ values of 0.2, 0.05, and 0.5 μM for *AChE* in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis .

Edrophonium-d5 chloride

Edrophonium-d₅ chloride is the deuterium labeled Edrophonium chloride (HY-B0882). Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has K_i values of 0.2, 0.2, and 0.4 μM and IC₅₀ values of 0.2, 0.05, and 0.5 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis .

HY-105853S

Pitofenone-d4
Pitofenone-d₄ is deuterium labeled Pitofenone (HY-105853). Pitofenone, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with K_is of 36 and 45 μM, respectively .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy

Name
Email *

	Sorry, but the email address you supplied was invalid.

erythrocyte AChE

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products