18 Results for "

gonadotropin secretion

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "gonadotropin secretion" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P1022
CAS No.: 374683-24-6
Synonyms: Metastin(human)
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

Kisspeptin-54(human) (Metastin(human)) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) binds to rat and human GPR54 receptors with Ki values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) inhibits tumor metastasis and stimulates the secretion of gonadotropin (LH) and testosterone .
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3
3 Cited Publications
Cat. No.: HY-P1022A
Synonyms: Metastin(human) TFA
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

Kisspeptin-54(human) TFA (Metastin(human) TFA) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) TFA binds to rat and human GPR54 receptors with Ki values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) TFA hinders tumor metastasis and stimulates gonadotropin secretion .
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2
2 Cited Publications
Cat. No.: HY-P0009A
CAS No.: 145672-81-7
Synonyms: SB-75 acetate
Target:  

GnRH Receptor Apoptosis

Research Areas:  

Endocrinology

Cetrorelix (SB-75) acetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix acetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix acetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix acetate is applicable for fertility assistance research .
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2
2 Cited Publications
Cat. No.: HY-P0009
CAS No.: 120287-85-6
Synonyms: SB-75
Target:  

GnRH Receptor Apoptosis

Research Areas:  

Endocrinology

Cetrorelix (SB-75) is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix is applicable for fertility assistance research .
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Cat. No.: HY-P3582
CAS No.: 96497-82-4
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

sGnRH-A is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A stimulates growth hormone secretion. sGnRH-A also can be used as an inducer of ovulation by artificial insemination .
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Cat. No.: HY-W017500
CAS No.: 17833-53-3
N-Methyl-DL-aspartic acid acts as an agonist for N-methyl-D-aspartic acid receptors and D-isomer-specific aspartate receptors. N-Methyl-DL-aspartic acid activates hypothalamic neurons that regulate gonadotropin-releasing hormone secretion, and stimulates prepubertal male rhesus monkeys to produce sustained intermittent gonadotropin-releasing hormone secretion and pulsatile luteinizing hormone secretion. N-Methyl-DL-aspartic acid activates excitatory effects mediated by N-methyl-D-aspartic acid receptors. N-Methyl-DL-aspartic acid exhibits convulsant effects, inducing clonic convulsions with loss of righting reflex, generalized tonic-clonic seizures or persistent clonic seizures. N-Methyl-DL-aspartic acid causes precocious puberty. N-Methyl-DL-aspartic acid can be used in studies related to convulsions and seizures .
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Cat. No.: HY-W009066
CAS No.: 1241-94-7
Synonyms: EHDPP; Octicizer
2-Ethylhexyl diphenyl phosphate is an organophosphate flame retardants (OPFRs) and a PPARG agonist (EC20: 2.04 µM). 2-Ethylhexyl diphenyl phosphate also inhibits ERRγ transcriptional activity (IC50: 1.3 µM). 2-Ethylhexyl diphenyl phosphate upregulates 3β-HSD1, human chorionic gonadotropin (hCG) and progesterone secretion. 2-Ethylhexyl diphenyl phosphate can be used in studies of female reproduction and fetal development .
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Cat. No.: HY-P1250
CAS No.: 311309-27-0
Synonyms: Neuropeptide VF(124-131)(human); Neuropeptide NPVF (human)
Research Areas:  

Neurological Disease

RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca 2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM .
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Cat. No.: HY-P3862
CAS No.: 110880-53-0
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

[MePhe7]-Neurokinin B is an neurokinin NK-3 receptor (NK3R) agonist with an IC50 value of 3 nM. [MePhe7]-Neurokinin B is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activation of the neurokinin-3 receptor (NK3R) .
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Cat. No.: HY-P3582A
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

sGnRH-A acetate is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A acetate stimulates growth hormone secretion. sGnRH-A acetate also can be used as an inducer of ovulation by artificial insemination .
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Cat. No.: HY-P3084
CAS No.: 107873-08-5
Synonyms: hF-GRP
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

Human follicular gonadotropin releasing peptide (hF-GRP) is a hormone peptide. Human follicular gonadotropin releasing peptide can stimulate pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion in vitro .
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Cat. No.: HY-P4904
CAS No.: 420088-80-8
Synonyms: Neuropeptide NPVF (rat)
Target:  

Peptides

Research Areas:  

Neurological Disease

RFRP-3 (rat) is a neuropeptide. RFRP-3 (rat) inhibits gonadotropin secretion, causing a marked increase in ghrelin mRNA and plasma growth hormone levels .
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Cat. No.: HY-P2082
CAS No.: 78255-70-6
Target:  

GnRH Receptor

Research Areas:  

Others

[D-pGlu1,D-Phe2,D-NaI3,6]-Gn-RH is a gonadotropin-releasing hormone (Gn-RH) agonist that has a dose-dependent inhibitory activity on progesterone secretion from cultured human granulosa cells.
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Cat. No.: HY-W019780
CAS No.: 75-27-4
Synonyms: Dichlorobromomethane
Research Areas:  

Metabolic Disease Cancer

Bromodichloromethane (Dichlorobromomethane) is a type of trihalomethane, commonly found in chlorinated drinking water for disinfection, and is a disinfection by-product. The bromination of bromodichloromethane can cause the formation of mutagenic intermediates through the transformation mediated by glutathione S-transferase (GST). Bromodichloromethane inhibits the differentiation of human placental trophoblast cells and reduces the secretion of chorionic gonadotropin (CG). Bromodichloromethane has potential reproductive toxicity and carcinogenicity .
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Cat. No.: HY-P2446
CAS No.: 83539-08-6
Synonyms: APTAA-LHRH
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

ORG 30276 (APTAA-LHRH) is a potent GnRH antagonist that effectively reduces serum LH and FSH levels in male rats. ORG 30276 significantly decreases unoccupied pituitary GnRH receptors, leading to suppressed gonadotropin secretion. ORG 30276 treatment results in a considerable reduction in mRNA levels of gonadotropin beta-subunits in the pituitary gland. ORG 30276's effects on gonadotropin dynamics can be selectively reversed by the replacement of specific sex steroids, with androgens being particularly effective for the FSH beta-subunit mRNA levels.
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Cat. No.: HY-P1250A
Synonyms: Neuropeptide VF(124-131)(human) TFA; Neuropeptide NPVF (human) TFA
Research Areas:  

Neurological Disease

RFRP-3 (Neuropeptide VF(124-131))(human) TFA, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca 2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM .
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Cat. No.: HY-P0009S1
Synonyms: SB-75-d10
Cetrorelix-d10 (SB-75-d10) is the d10-labeled Cetrorelix (HY-P0009). Cetrorelix is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix is applicable for fertility assistance research .
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Cat. No.: HY-117076A
CAS No.: 61665-15-4
Synonyms: (R)-R 2858; RU 16117
(R)-Moxestrol ((R)-R 2858; RU 16117) is an orally active weak partial agonist-antagonist of estrogen receptor (ER). (R)-Moxestrol binds to estrogen receptor to form a rapidly dissociating complex, reduces the levels of estrogen and prolactin receptor, exerts weak estrogenic effects at low doses, and displays anti-estrogenic effects at high doses or when competing with Estradiol (E2) (HY-B0141). (R)-Moxestrol can be used in research related to breast cancer and postmenopausal estrogen deficiency (menopausal symptoms, severe osteoporosis) .
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