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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
hERG (Kv11.1)
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "hERG (Kv11.1)" in MCE Product Catalog:
Target:
Research Areas:
NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels. NS3623 activates the IKr and Ito currents and has antiarrhythmic effect. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels .
Cat. No.: HY-120375
CAS No.: 1821638-40-7
Target:
Research Areas:
LUF7346 is a potent Kv11.1 (hERG) channel negative allosteric modulator, with an IC50 of 35.6 ± 3.2 nM .
Cat. No.: HY-P1440A
Target:
Research Areas:
Cat. No.: HY-181103
CAS No.: 2059904-64-0
Target:
Research Areas:
ERG-IN-6 (compound (+)-(S)-5a) is a μ-opioid receptor activator with an EC50 of 0.12 nM. ERG-IN-6 also is a hERG (Kv11.1) potassium channel inhibitor with an IC50 of 0.681 μM. ERG-IN-6 can be used for the research of pain .
Target:
Research Areas:
A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator. A-935142 enhances hERG current in a complex manner by facilitation of activation, reduction of inactivation, and slowing of deactivation, and abbreviates atrial and ventricular repolarization .
Cat. No.: HY-P811227
Synonyms: ERG, ERG1, hERG, KCNH2, Voltage-gated inwardly rectifying potassium channel KCNH2, Eag homolog, Ether-a-go-go-related gene potassium channel 1, Potassium voltage-gated channel subfamily H member 2, Voltage-gated potassium channel subunit Kv11.1, ERG-1, Eag-related protein 1, Ether-a-go-go-related protein 1, H-ERG, hERG-1, hERG1
Cat. No.: HY-P701834
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KCNH2; hERG1; Prev. LQT2; Potassium Voltage-Gated Channel Subfamily H Eag-Related Member 2; hERG; Ether-A-Go-Go-Related Potassium Channel Protein; Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2; Voltage-Gated Channel Subfamily H Member 2; Voltage-Gated Inwardly Rectifying Potassium Channel KCNH2; Human Ether-A-Go-Go-Related Gene; Ether-A-Go-Go-Related Gene Potassium Channel 1; Uncharacterized Protein KCNH2; Voltage-Gated Potassium Channel Subunit Kv11.1; Human Ether-A-Go-Go-Related; Kv11.1; Potassium Channel hERG1; Erg1; Potassium Channel hERG; Ether-A-Go-Go-Related Protein 1; KCNH2 Protein; Long QT Syndrome Type 2; hERG-1; Eag-Related Protein 1; SQT1; Eag Homolog; ERG1; ERG-1; ERG; H-ERG; Potassium Voltage-Gated Channel Subfamily H Member 2; Potassium Channel, Voltage Gated Eag Related Subfamily H, Member 2
Species:
Human
Source:
HEK293
Cat. No.: HY-P703937
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: KCNH2; hERG1; Prev. LQT2; Potassium Voltage-Gated Channel Subfamily H Eag-Related Member 2; hERG; Ether-A-Go-Go-Related Potassium Channel Protein; Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2; Voltage-Gated Channel Subfamily H Member 2; Voltage-Gated Inwardly Rectifying Potassium Channel KCNH2; Human Ether-A-Go-Go-Related Gene; Ether-A-Go-Go-Related Gene Potassium Channel 1; Uncharacterized Protein KCNH2; Voltage-Gated Potassium Channel Subunit Kv11.1; Human Ether-A-Go-Go-Related; Kv11.1; Potassium Channel hERG1; Erg1; Potassium Channel hERG; Ether-A-Go-Go-Related Protein 1; KCNH2 Protein; Long QT Syndrome Type 2; hERG-1; Eag-Related Protein 1; SQT1; Eag Homolog; ERG1; ERG-1; ERG; H-ERG; Potassium Voltage-Gated Channel Subfamily H Member 2; Potassium Channel, Voltage Gated Eag Related Subfamily H, Member 2
Species:
Human
Source:
HEK293
Cat. No.: HY-108586R
CAS No.: 343630-41-1
Target:
Research Areas:
NS3623 (Standard) is the analytical standard of NS3623 (HY-108586). This product is intended for research and analytical applications. NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels. NS3623 activates the IKr and Ito currents and has antiarrhythmic effect. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels .
Cat. No.: HY-184190
Research Areas:
ERG-IN-7 is a Nav1.5, Cav1.2 and Kv11.1 inhibitor with IC50 values of 10.34 μM, 21.01 μM, and 16.385 μM for human Nav1.5, Cav1.2, and Kv11.1, respectively. ERG-IN-7 prolongs action potentials, reduces conduction velocity, and restores cardiac function. ERG-IN-7 can be used for the research of ventricular arrhythmia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
