2 Results for "

imiquimod-induced dermatitis

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "imiquimod-induced dermatitis" in MCE Product Catalog:

Cat. No.: HY-187958
CAS No.: 91837-56-8
Research Areas:  

Inflammation/Immunology

PO-322 is a selective SGK1 inhibitor with an IC50 of 54 nM. PO-322 reduces NDRG1 phosphorylation through inhibition of SGK1. PO-322 inhibits T cell proliferation and the production of IL-17, IFN-γ, and IL-6, accompanied by upregulated phosphorylation of p70S6K and STAT5. PO-322 exhibits immunosuppressive activity both in vitro and in vivo, and attenuates DNFB-induced delayed-type hypersensitivity and Imiquimod (HY-B0180)-induced psoriasis-like dermatitis. PO-322 is useful for research related to autoimmune diseases and psoriasis .
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Cat. No.: HY-186214
CAS No.: 3034837-81-2
Research Areas:  

Inflammation/Immunology

PDE4-IN-36 is a phosphodiesterase 4 (PDE4) inhibitor with significant inhibitory activity at 10 μM. PDE4-IN-36 can be used in the research of psoriasis and atopic dermatitis .
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