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Art. -Nr.: HY-186214

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PDE4-IN-36

PDE4-IN-36 is a phosphodiesterase 4 (PDE4) inhibitor with significant inhibitory activity at 10 μM. PDE4-IN-36 can be used in the research of psoriasis and atopic dermatitis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 3034837-81-2
Formel: C₂₃H₂₄O₈
Molecular Weight:428.43

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

PDE4-IN-36 Chemical Structure

CAS. Nr.: 3034837-81-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

PDE4-IN-36 is a phosphodiesterase 4 (PDE4) inhibitor with significant inhibitory activity at 10 μM. PDE4-IN-36 can be used in the research of psoriasis and atopic dermatitis^[1].

IC₅₀ & Target^[1]

PDE4

Alle Phosphodiesterase (PDE) Isoform-spezifische Produkte anzeigen :

In Vitro

PDE4-IN-36 (Compound 8b) (0.1-10 μM) inhibits the activity of recombinant PDE4 protein, with an inhibition rate of 51-75% at a concentration of 10 μM and 1-25% at a concentration of 1 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3034837-81-2
Molecular Weight 428.43
Formel C₂₃H₂₄O₈
SMILES

OC(C1C2=CC(/C=C/C(O)=O)=CC(OCC)=C2OC1C3=CC(OCC)=C(C=C3)OC)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Li YM, et al. Phosphodiesterase-4 inhibitor, pharmaceutical composition comprising same, and use thereof. WO2024239762A1. WIPO. 2024-11-28.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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PDE4-IN-36

Alle Phosphodiesterase (PDE) Isoform-spezifische Produkte anzeigen