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inositol phospholipid

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By Targets:	Bacterial (1) Biochemical Assay Reagents (1) Calcium Channel (1) Endogenous Metabolite (1) Fluorescent Dye (1) Liposome (1) Neurokinin Receptor (1) Phospholipase (1) PKC (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Infection (1) Metabolic Disease (10) Neurological Disease (1)
Oligonucleotides:	Phospholipids (7)

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Targets Recommended: IRE1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2817

Phospholipase C PLCs	Phospholipase	Infection Metabolic Disease
Phospholipase C (PLCs) is a class of phospholipases. Phospholipase C participates in cellular signaling and regulation by virtue of its ability to hydrolyze membrane phospholipids into di-acyl-glycerol (DAG) and inositol triphosphate (IP3), which further causes the activation of other signaling pathways involved in various processes, including immune response .

HY-W145699

D-myo-Inositol 4-monophosphate	Biochemical Assay Reagents Endogenous Metabolite	Others
D-myo-Inositol 4-mono-phosphate, also known as IMP, is a phosphorylated form of inositol that is commonly found in various metabolic pathways, especially in the biosynthesis of phospholipids and cell signaling molecules. D-myo-Inositol 4-mono-phosphate has unique chemical properties that make it an important intermediate in the production of second messengers, such as inositol triphosphate (IP3) and diacylglycerol (DAG), which signal in cells plays a key role in. D-myo-Inositol 4-mono-phosphate is also used in dietary supplements and pharmaceuticals because of its potential health benefits, including improved insulin sensitivity and cognitive function.

HY-175086

PtdIns-(3,4,5)-P3-fluorescein triethylammonium DOPI-3,4,5-P3-fluorescein triethylammonium; PI(3,4,5)P3-fluorescein triethylammonium; PIP3[3',4',5']-fluorescein triethylammonium	Fluorescent Dye	Others
PtdIns-(3,4,5)-P3 is a second messenger. PtdIns-(3,4,5)-P3-fluorescein triethylammonium is a fluorescent probe that can detect any protein that has a high-affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids .

HY-101607A

KT-362 free acid	Calcium Channel	Cardiovascular Disease
KT-362 free acid is an intracellular calcium antagonist with antiarrhythmic and vasodilatory effects. KT-362 free acid shows an antagonistic effect against norepinephrine (NE) induced vasoconstriction response, achieved by reducing inositol phospholipid hydrolysis, thereby reducing intracellular calcium mobilization. KT-362 free acid can be used to study the contraction and relaxation mechanisms of vascular smooth muscle, especially in exploring the role of intracellular calcium mobilization and inositol phospholipid hydrolysis in vascular contraction .

HY-W414697

4-Hydroxysphinganine (C17 base) D-Ribo-phytosphingosine (C17 base)	Bacterial	Others
4-Hydroxysphinganine C17 base (D-Ribo-phytosphingosine C17 base), also known as D-ribo-phytosphingosine or PHS, is a crucial compound present in the membranes of fungi, plants, bacteria, marine organisms, and mammalian tissues. It plays a vital role in preserving the structural integrity of membranes, regulating cellular growth, and mediating the heat stress response in yeast. Additionally, PHS serves as a precursor for the synthesis of important lipid mediators such as PHS 1-phosphate, inositol phosphorylceramide, and KRN7000 (the α-anomer of galactosylceramide). Furthermore, this phospholipid promotes keratinocyte differentiation, making it a valuable active ingredient in cosmetic formulations.

HY-148972

PI(3,5)P2 diC16	Liposome	Others
PI(3,5)P2 diC16 is a synthetic inositol phospholipid. PI(3,5)P2 diC16 is a lipid molecule .

HY-P2593

L-659874	Neurokinin Receptor	Neurological Disease
L-659874 is a selective NK2 receptor antagonist with an IC₅₀ value of 0.49 μM in hamsters. L-659874 inhibits NK2 receptor-mediated hydrolysis of inositol phospholipids. L-659874 could be used for research on the correlation between pain signal transduction and smooth muscle responses. .

HY-W788040

Inositol 1,3,4,5-tetraphosphate tetraammonium	Others	Others
Inositol 1,3,4,5-tetraphosphate (tetraammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-150135A

D-myo-Inositol-1,4,5-triphosphate triammonium	Others	Metabolic Disease
D-myo-Inositol-1,4,5-triphosphate (triammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-N16138

18:0 PI DSPI (18:0/18:0)	Others	Metabolic Disease
18:0 PI is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-W725804

15:0-18:1 PI ammonium	Others	Metabolic Disease
15:0-18:1 PI (ammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-157619

16:0-18:1 PI ammonium 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol ammonium	Others	Metabolic Disease
16:0-18:1 PI (ammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-148303

Phosphatidylinositol bis-4,5-phosphate,1,2-dipalmitoyl	Others	Others
Phosphatidylinositol bis-4,5-phosphate,1,2-dipalmitoyl is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-E70853

PKCδ Recombinant Human Active Protein Kinase	PKC	Cancer
PKCδ is a PKC isoform. PKCδ is expressed ubiquitously among cells and tissues. It is activated by diacylglycerol produced by receptor-mediated hydrolysis of membrane inositol phospholipids as well as by tumor-promoting phorbol ester through the binding of these compounds to the C1 region in its regulatory domain. PKCδ Recombinant Human Active Protein Kinase is a recombinant PKCδ protein that can be used to study PKCδ-related functions .

Cat. No.	Product Name	Type

HY-W145699

D-myo-Inositol 4-monophosphate	Biochemical Assay Reagents
D-myo-Inositol 4-mono-phosphate, also known as IMP, is a phosphorylated form of inositol that is commonly found in various metabolic pathways, especially in the biosynthesis of phospholipids and cell signaling molecules. D-myo-Inositol 4-mono-phosphate has unique chemical properties that make it an important intermediate in the production of second messengers, such as inositol triphosphate (IP3) and diacylglycerol (DAG), which signal in cells plays a key role in. D-myo-Inositol 4-mono-phosphate is also used in dietary supplements and pharmaceuticals because of its potential health benefits, including improved insulin sensitivity and cognitive function.

D-myo-Inositol 4-monophosphate

Biochemical Assay Reagents

D-myo-Inositol 4-mono-phosphate, also known as IMP, is a phosphorylated form of inositol that is commonly found in various metabolic pathways, especially in the biosynthesis of phospholipids and cell signaling molecules. D-myo-Inositol 4-mono-phosphate has unique chemical properties that make it an important intermediate in the production of second messengers, such as inositol triphosphate (IP3) and diacylglycerol (DAG), which signal in cells plays a key role in. D-myo-Inositol 4-mono-phosphate is also used in dietary supplements and pharmaceuticals because of its potential health benefits, including improved insulin sensitivity and cognitive function.

Cat. No.	Product Name	Target	Research Area

HY-P2593

L-659874	Neurokinin Receptor	Neurological Disease
L-659874 is a selective NK2 receptor antagonist with an IC₅₀ value of 0.49 μM in hamsters. L-659874 inhibits NK2 receptor-mediated hydrolysis of inositol phospholipids. L-659874 could be used for research on the correlation between pain signal transduction and smooth muscle responses. .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W145699

D-myo-Inositol 4-monophosphate	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Biochemical Assay Reagents Endogenous Metabolite
D-myo-Inositol 4-mono-phosphate, also known as IMP, is a phosphorylated form of inositol that is commonly found in various metabolic pathways, especially in the biosynthesis of phospholipids and cell signaling molecules. D-myo-Inositol 4-mono-phosphate has unique chemical properties that make it an important intermediate in the production of second messengers, such as inositol triphosphate (IP3) and diacylglycerol (DAG), which signal in cells plays a key role in. D-myo-Inositol 4-mono-phosphate is also used in dietary supplements and pharmaceuticals because of its potential health benefits, including improved insulin sensitivity and cognitive function.

Cat. No.	Product Name		Classification

HY-157709

18:1 PI ammonium DOPI(18:1(9Z)/18:1(9Z)) ammonium		Phospholipids
18:1 PI (ammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-W790474A

IP3(1,3,4) ammonium		Phospholipids
IP3(1,3,4) (ammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-157701

18:1 PI(4)P		Phospholipids
18:1 PI(4)P is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-157640

18:0-20:4 PI(5)P diammonium		Phospholipids
18:0-20:4 PI(5)P (diammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-157621

16:0-18:1 PI(4)P ammonium		Phospholipids
16:0-18:1 PI(4)P (ammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-157705

18:1 PI(3,5)P2 triammonium PIP2[3',5'](18:1(9Z)/18:1(9Z)) triammonium		Phospholipids
18:1 PI(3,5)P2 (triammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

HY-158572

PtdIns-(4,5)-P2 (1,2-dipalmitoyl) trisodium		Phospholipids
PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (trisodium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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inositol phospholipid

Inhibitors & Agonists

Biochemical Assay Reagents

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