40289-37-0
Chemical Structure
4-Hydroxysphinganine (C17 base)
Synonym(s): D-Ribo-phytosphingosine (C17 base)
- CAS No.: 40289-37-0
- Formula:C17H37NO3
- Molecular Weight:303.48
IUPAC Name: (2S,3S,4R)-2-aminoheptadecane-1,3,4-triol
InChIKey: NKOLYWXODIHTSI-BBWFWOEESA-N
SMILES: [C@@H](CCCCCCCCCCCCC)([C@H]([C@H](CO)N)O)O
Biological Activity: 4-Hydroxysphinganine C17 base (D-Ribo-phytosphingosine C17 base), also known as D-ribo-phytosphingosine or PHS, is a crucial compound present in the membranes of fungi, plants, bacteria, marine organisms, and mammalian tissues. It plays a vital role in preserving the structural integrity of membranes, regulating cellular growth, and mediating the heat stress response in yeast. Additionally, PHS serves as a precursor for the synthesis of important lipid mediators such as PHS 1-phosphate, inositol phosphorylceramide, and KRN7000 (the α-anomer of galactosylceramide). Furthermore, this phospholipid promotes keratinocyte differentiation, making it a valuable active ingredient in cosmetic formulations.
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4-Hydroxysphinganine (C17 base) | 4-Hydroxysphinganine C17 base (D-Ribo-phytosphingosine C17 base), also known as D-ribo-phytosphingosine or PHS, is a crucial compound present in the membranes of fungi, plants, bacteria, marine organisms, and mammalian tissues. It plays a vital role in preserving the structural integrity of membranes, regulating cellular growth, and mediating the heat stress response in yeast. Additionally, PHS serves as a precursor for the synthesis of important lipid mediators such as PHS 1-phosphate, inositol phosphorylceramide, and KRN7000 (the α-anomer of galactosylceramide). Furthermore, this phospholipid promotes keratinocyte differentiation, making it a valuable active ingredient in cosmetic formulations. | |||||||||||||||||||||
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