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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
integrin α2β1
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "integrin α2β1" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P1408
CAS No.: 404882-00-4
3
3 Cited Publications
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TC-I 15 (TC-I-15) is a type of allosteric collagen-binding integrin α2β1 inhibitor, and it also inhibits α1β1 and α11β1. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition. TC-I 15 prevents the formation of a pre-metastatic microenvironment by inhibiting the uptake of cancer-associated fibroblast (CAF) extracellular vesicles (EVs) by lung fibroblasts, which reduces the metastasis of salivary gland adenocystic carcinoma (SACC) to the lungs in mouse models, .
3
3
1
1 Cited Publications
Cat. No.: HY-P700752
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGA2; Alpha 2 integrin; Prev. CD49B; Very Late Activation Protein 2 Receptor, Alpha-2 Subunit; GPIa; Very Late Activation Receptor Alpha-2 Subunit; CD49 Antigen-Like Family Member B; Human Platelet Alloantigen System 5; Platelet Membrane Glycoprotein Ia
Species:
Human
Source:
HEK293
Cat. No.: HY-P11328
CAS No.: 245120-10-9
Cat. No.: HY-P11087
CAS No.: 134335-45-8
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BOP sodium is a potent and selective dual α9β1/α4β1 integrin inhibitor with Kd values in the picomolar range. BOP sodium shows the rapid and preferential mobilization of hematopoietic stem cell (HSC) and progenitors. BOP sodium has little inhibitory activity on α4β7, α1β1, α2β1, and α5β1, αIIBβ3 integrins .
Cat. No.: HY-P10941A
Research Areas:
Cat. No.: HY-W654264
Target:
Cat. No.: HY-P10941
CAS No.: 2027476-29-3
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Cat. No.: HY-177331
CAS No.: 1259029-47-4
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BTT-3034, a sulfonamide derivative, is an α2β1 integrin inhibitor. BTT-3034 inhibits cell adhesion to rat tail collagen I with an EC50 of 160 nM and a corresponding Emaxof 86%. BTT-3034 inhibits collagen binding by an α2 variant carrying the conformationally activating E318W mutation .
Cat. No.: HY-107588R
CAS No.: 916734-43-5
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TC-I 15 (Standard) is the analytical standard of TC-I 15 (HY-107588). This product is intended for research and analytical applications. TC-I 15 (TC-I-15) is a type of allosteric collagen-binding integrin α2β1 inhibitor, and it also inhibits α1β1 and α11β1. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition. TC-I 15 prevents the formation of a pre-metastatic microenvironment by inhibiting the uptake of cancer-associated fibroblast (CAF) extracellular vesicles (EVs) by lung fibroblasts, which reduces the metastasis of salivary gland adenocystic carcinoma (SACC) to the lungs in mouse models, .
Cat. No.: HY-P700753
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ITGA2; Alpha 2 integrin; Prev. CD49B; Very Late Activation Protein 2 Receptor, Alpha-2 Subunit; GPIa; Very Late Activation Receptor Alpha-2 Subunit; CD49 Antigen-Like Family Member B; Human Platelet Alloantigen System 5; Platelet Membrane Glycoprotein Ia
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P703694
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGA2; Alpha 2 integrin; Prev. CD49B; Very Late Activation Protein 2 Receptor, Alpha-2 Subunit; GPIa; Very Late Activation Receptor Alpha-2 Subunit; CD49 Antigen-Like Family Member B; Human Platelet Alloantigen System 5; Platelet Membrane Glycoprotein Ia
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P705486
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGA2; Alpha 2 integrin; Prev. CD49B; Very Late Activation Protein 2 Receptor, Alpha-2 Subunit; GPIa; Very Late Activation Receptor Alpha-2 Subunit; CD49 Antigen-Like Family Member B; Human Platelet Alloantigen System 5; Platelet Membrane Glycoprotein Ia
Species:
Human
Source:
HEK293
Cat. No.: HY-P11753A
Target:
Research Areas:
Cat. No.: HY-P11753
CAS No.: 1187540-64-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
