Search Result
Results for "
iridoids
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N0820
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- HY-N0664
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Bacterial
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Infection
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
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Aucubin is an iridoid glycoside component that acn be found in E. ulmoides. Aucubin can cross the blood-brain barrier (BBB) and has anti-anxiety, antidepressive and anti-neuroinflammatory effects. Aucubin has many biological activities, such as antioxidant, anti-aging, anti-inflammatory, antimicrobial, anti-fibrotic, anti-cancer, hepatoprotective, neuroprotective and osteoprotective effects .
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- HY-125598
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Drug Intermediate
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Others
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Secologanin is an iridoid monoterpenoid glucoside found in the leaves of Lonicera tatarica and a key precursor for thousands of natural monoterpenoid alkaloids .
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- HY-N0914
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- HY-N2015
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Others
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Neurological Disease
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Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep .
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- HY-W587415
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Others
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Others
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Nepetalactol is an iridoid. It has been found in Actinidia polygama (the silver vine) as a major cat attractant, and a mosquito repellent.
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- HY-N1503
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6α-Hydroxygeniposide; Deacetylasperulosidic acid methyl ester
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Others
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Metabolic Disease
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Methyl deacetylasperulosidate is an iridoid and shows purgative effects in mice and lowers the blood glucose level in normal mice .
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- HY-N8314
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Others
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Others
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8-Epiloganic acid, an iridoid glucoside, can be found in Linaria cymbalaria (Scrophulariaceae) .
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- HY-N2772
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7-Deoxy-8-epiloganic acid
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Others
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Neurological Disease
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8-Epideoxyloganic acid (7-Deoxy-8-epiloganic acid), an iridoid glucoside, can be found in Incarvillea delavayi. 8-Epideoxyloganic acid exhibits weak antinociceptive activity .
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- HY-N5086
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- HY-N0664R
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Reference Standards
Bacterial
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Infection
Neurological Disease
Inflammation/Immunology
Cancer
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Aucubin (Standard) is the analytical standard of Aucubin. This product is intended for research and analytical applications. Aucubin, an iridoid glucoside, is isolated from Plantago asiatica, Eucommia ulmoides, the leaves of Aucuba japonica and more recently from butterfly larva. Aucubin has many biological activities, such as antioxidant, anti-aging, anti-inflammatory, antimicrobial, anti-fibrotic, anti-cancer, hepatoprotective, neuroprotective and osteoprotective effects .
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- HY-N2400
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- HY-N0409
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Others
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Inflammation/Immunology
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Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .
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- HY-N8046
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Others
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Others
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Gardoside is an iridoid glycoside that can be found in the roots of L. alba .
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- HY-N9352
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Others
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Others
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Cantleyoside is a natiural iridoid glycoside that could be found in the Roots of Dipsacus asper .
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- HY-N4092
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Others
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Others
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Shanziside is a iridoid glucoside isolated from Phlomis tuberosa L .
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- HY-N10590
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Deacetylalpinoside
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Others
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Others
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Arborescosidic acid (Deacetylalpinoside) is a carboxylated iridoid glucoside, that can be isolated from Veronica beccabunga (brooklime) .
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- HY-N4306
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Others
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Cancer
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Sarracenin is a iridoid isolated from roots and rhizomes of Patrinia heterophylla. Sarracenin shows cytotoxic activities against tumor cells .
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- HY-N1155
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- HY-N16570
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Others
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Others
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6-O-veratryl catalposide is an iridoid glucoside can be found in Tecomella undulata .
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- HY-N12840
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- HY-N4120
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Autophagy
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Metabolic Disease
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Valechlorine, an iridoid, is an autophagy enhancer. Valechlorine is effective in alleviating fatty liver by acting as an autophagy enhancer to break down lipid droplets. Valechlorine can be used for the study of nonalcoholic fatty liver disease (NAFLD) .
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- HY-N0820R
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Catalpinoside (Standard)
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Reference Standards
HBV
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Infection
Neurological Disease
Inflammation/Immunology
Cancer
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Catalpol (Standard) is the analytical standard of Catalpol. This product is intended for research and analytical applications. Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .
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- HY-N3030
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- HY-N0916
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Danmelittoside
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Bacterial
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Inflammation/Immunology
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Monomelittoside is a iridoid glycoside with antibacterial activity. Monomelittoside inhibits dental caries pathogen Streptococcus.
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- HY-N6245
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- HY-N16596
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Others
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Others
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V1-iridoid is a type of iridoid compound. V1-iridoid has been identified as the characteristic component of the plants G. humifusumBieb. and G. verumL. .
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- HY-N2712
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Others
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Others
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6''-O-trans-Feruloylcatalpol is a natural iridoid glycoside compound .
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- HY-N12202
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Others
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Others
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6′-O-β-D-Glucopyranosylphlorigidoside C (compound 1) is an iridoid glycoside that can be isolated from Lamiophlomis rotata .
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- HY-N4092R
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Influenza Virus
Reference Standards
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Others
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Shanziside (Standard) is the analytical standard of Shanziside. This product is intended for research and analytical applications. Shanziside is a iridoid glucoside isolated from Phlomis tuberosa L .
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- HY-124881
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Others
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Others
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Scandoside is a natural product that can be isolated from iridoid glucosides of Paederia scandens .
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- HY-N1206
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6-O-(E)-p-Coumaroylcatalpol
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Others
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Others
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Specioside is a novel iridoid glycoside extracted from Catalpa speciosa Warder (Bignoniaceae) .
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- HY-N8759
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Others
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Inflammation/Immunology
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Vogeloside is an iridoid that can be isolated from the roots of Triosteum pinnatifidum. Vogeloside inhibits nitric oxide production in LPS-activated macrophages .
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- HY-N11794
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Others
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Others
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7-Ketologanin is an iridoid glucoside. 7-Ketologanin can be isolated from the Stems of Viburnum erosum. 7-Ketologanin involves in biosynthetic pathway of oleuropein. Oleuropein, is a bioactive phenolic compound, modulates several oncogenic signalling pathways .
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- HY-133109
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Others
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Others
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Trachelosiaside is a natural organic compound belonging to the class of iridoid glycosides. Trachelosiaside is found in various plant species, especially in the roots of Trachelospermum jasminoides. Trachelosiaside has potential medicinal properties, such as anti-inflammatory, antioxidant, and anti-tumor effects. Trachelosiaside has industrial applications in the production of food supplements, cosmetics and pharmaceuticals.
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- HY-W750451
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Akt
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Cancer
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Reptoside, an iridoid glucoside, is a DNA damaging active agent. Reptoside has strong interactions with Trp352 and Tyr335 in AKT1 .
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- HY-133800
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Biochemical Assay Reagents
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Cancer
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Volvaltrate B is an anticancer agent, iridoid, can be obtained from the root of valerian (Valeriana officinalis). Volvaltrate B is effective against ovarian tumors in female mice. Volvaltrate B has the potential to study cancer .
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- HY-N0914R
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- HY-160121
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Patrinoside aglycone
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Apoptosis
NO Synthase
TNF Receptor
Interleukin Related
PGE synthase
COX
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Inflammation/Immunology
Cancer
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Patrinoside aglucone (Compound 8) is an iridoid glucoside that can be isolated from the Valeriana tuberosa. Patrinoside aglucone has potent anticancer activity with G2/M phase tumor cell cycle arrest and apoptosis induction. Patrinoside aglucone also significantly inhibits the proliferation of cancer stem cells (such as MDA-MB-231 and U-251MG cells). Patrinoside aglucone has great anti-inflammatory activity by inhibiting NO release (IC50: 43.44 μM) and significantly reduces the level of TNF-α, IL-1β, IL-6, PGE2 and COX-2 .
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- HY-N11659
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- HY-N13109
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Others
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Others
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Caprarioside is an iridoid glycoside that can be isolated from Capraria biflora L. .
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- HY-N4001
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Others
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Others
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Isoboonein acetate is a Iridoids product that can be isolated from the herbs of Rauvolfia vomitoria .
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- HY-N3978
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Others
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Others
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Griselinoside is a Iridoids product that can be isolated from the herbs of Toricellia angulata .
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- HY-N9007
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Others
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Others
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Isojasminin is a Iridoids product that can be isolated from the stems of Jasminum nudiflorum .
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- HY-N3948
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Others
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Others
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Globularin is a Iridoids product that can be isolated from the herbs of Globularia alypum .
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- HY-N3959
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Glycozolinol
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Others
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Others
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Glycozolinine (Glycozolinol) is a Iridoids product that can be isolated from the herbs of Duranta repens .
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- HY-N8586
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Others
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Others
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Rehmaglutin D is a Iridoids product that can be isolated from the barks of Ailanthus integrifolia .
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- HY-N8972
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Others
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Others
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Nudifloside D is a Iridoids product that can be isolated from the leaves of Jasminum nudiflorum. .
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- HY-N8992
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Others
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Others
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Nudifloside B is a Iridoids product that can be isolated from the stems of Jasminum nudiflorum. .
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- HY-N9293
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Others
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Others
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Jasminin is a Iridoids product that can be isolated from the leaves of Jasminum primulinum HEMSL. .
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- HY-N7342
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Others
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Others
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Valeriotriate B is a Iridoids product that can be isolated from the herbs of Valeriana jatamansi .
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- HY-133198
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NO Synthase
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Others
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Valeriandoid B is a Iridoids product that can be isolated from the herbs of Valeriana jatamansi .
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- HY-N3791
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Others
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Others
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Durantoside II is a Iridoids product that can be isolated from the herbs of Duranta repens .
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- HY-N9346
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- HY-N1277
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Others
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Others
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Dimethyl secologanoside (compound 2) is an e iridoid isolated from the leaves of Khaya senegalensis .
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- HY-N1893
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(-)-4-epi-Alyxialactone
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Others
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Others
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4-epi-Alyxialactone is a non-glycosidic iridoid, that can be isolated from Cymbaria mongolica .
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- HY-N4221
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Others
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Others
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6'-O-Cinnamoyl harpagide is an iridoid glycoside isolated from the roots of Scrophularia ningpoensis .
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- HY-N2839
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Tyrosinase
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Others
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Allamandicin is an iridoid lactones. Allamandicin can be isolated from the roots of Allamanda cathartica. Allamandicin is an inhibitor of tyrosinase .
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- HY-N3839
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7-epi-Vogeloside; Nervoside; Epivogeloside
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Others
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Others
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epi-Vogeloside is a secoiridoid glycoside and a iridoid glucoside, which can be isolated from Lonicera japonica Thunb .
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- HY-N17947
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Others
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Others
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7-Epi-loganin is an iridoid glucoside found in the flower buds of Lonicera japonica .
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- HY-N11712
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Others
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Others
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8-Dehydroxyshanzhiside is an iridoid glycoside that can be isolated from Lamiophlomis rotata .
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- HY-N17900
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Others
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Others
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Secologanoside 7-methyl ester (compound 2) is an iridoid glycoside. Secologanoside 7-methyl ester can be found in the leaves of Syringa reticulata .
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- HY-N17922
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Others
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Others
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Genameside A is an iridoid glucoside found in the fruit of Genipa americana L .
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- HY-N19759
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- HY-N17667
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Others
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Others
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6’’-O-trans-p-Coumaroylgenipin gentiobioside (compound 2) is an iridoid glucoside that can be found in Gardenia jasminoides .
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- HY-N19779
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Scrospioside A; Scropheanoside III
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Drug Derivative
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Metabolic Disease
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Scropolioside D (Scrospioside A; Scropheanoside III) is an orally active acylated iridoid glycoside found in the roots of Scrophularia saharae with antidiabetic activity .
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- HY-N2730
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- HY-N17840
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Drug Derivative
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Others
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6α-Methoxygeniposidic acid is an iridoid glucoside found in the leaves of Hedyotis tenelliflora Blume (Rubiaceae) .
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- HY-N17467
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Drug Derivative
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Metabolic Disease
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Forsydoitriside A is an iridoid glycoside trimer found in the fruits of Forsythia suspensa. Forsydoitriside A shows no significant hepatoprotective activity against Acetaminophen (HY-66005)-induced damage in liver cells at 10 μM .
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- HY-N18043
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Drug Derivative
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Others
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Rehmaglutin C is an iridoid lactone.Rehmaglutin C can be found in the dried root of Rehmannia glutinosa LiBosCH .
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- HY-N17920
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Others
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Neurological Disease
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6α-Methoxygeniposide is a geniposide-type iridoid compound present in the leaves of Gardenia jasminoides cv. fortuneana HARA. 6α-Methoxygeniposide induces neurite outgrowth in pheochromocytoma cells .
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- HY-N9817
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- HY-N17065
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- HY-N17113
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- HY-N17090
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- HY-W748495
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- HY-N13796
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- HY-N17036
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- HY-N7566
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- HY-125543
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Others
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Others
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Karsoside is an iridoid glycoside that can be isolated from Scrophularia ilwensis .
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- HY-N13331
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Others
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Others
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Demethylsecologanol is an iridoid. Demethylsecologanol can be isolated from Lonicera Caulis (Caprifoliaceae) .
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- HY-N1211
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Others
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Others
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Splendoside is a Iridoids product that can be isolated from the fruits of Vaccinium uliginosum. .
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- HY-N2955
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Others
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Others
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Borreriagenin is a Iridoids product that can be isolated from the herbs of Borreria verticillata .
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- HY-N9733
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Others
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Others
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2-Methoxyanofinic acid is an iridoid compound that can be found in Gentiana macrophylla .
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- HY-N17038
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- HY-N0965
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Others
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Others
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(E)-Aldosecologanin is a Iridoids product that can be isolated from the herbs of Lonicera japonica .
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- HY-N2966
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Others
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Others
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Buergerinin B is a Iridoids product that can be isolated from the roots of Scrophularia ningpoensis .
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- HY-N3881
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Others
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Others
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Euphroside is a Iridoids product that can be isolated from the aerial parts of Euphrasia pectinata. .
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- HY-N18704
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Others
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Others
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Euphrasia officinalis extract contains iridoid glycosides and flavonoids, and can be used in cosmetic research.
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- HY-N9178
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Others
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Others
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Nudifloside C is a Iridoids product that can be isolated from the stems of Jasminum nudiflorum. .
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- HY-N2711
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Others
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Others
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Curvifloruside F is a Iridoids product that can be isolated from the roots of Scrophularia ningpoensis Hemsl. .
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- HY-N9008
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Others
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Others
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4''-Hydroxyisojasminin is a Iridoids product that can be isolated from the roots of Jasminum sambac .
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- HY-N1124
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TWC 1
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Others
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Others
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Triptocallic acid A (TWC 1) is a Iridoids product that can be isolated from the herbs of Vitex negundo .
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- HY-N1585
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Others
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Others
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15-Demethylplumieride is a Iridoids product that can be isolated from the barks of Plumeria rubra .
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- HY-N2928
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Others
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Others
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β-Dihydroplumericinic acid is a Iridoids product that can be isolated from the herbs of Plumeria rubra .
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- HY-N3080
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Others
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Others
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Phlorigidoside B is a Iridoids product that can be isolated from the roots of Lamiophlomis rotata (Benth.) Kudo .
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- HY-N2710
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Others
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Others
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6-Epiharpagide is a Iridoids product that can be isolated from the roots of Scrophularia ningpoensis Hemsl. .
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- HY-N1642
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Others
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Others
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1-O-Methyljatamanin D is a Iridoids product that can be isolated from the herbs of Valeriana jatamansi .
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- HY-N1008
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Others
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Others
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10-O-Caffeoyl deacetyldaphylloside is a Iridoids product that can be isolated from the fruits of Gardenia jasminoides .
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- HY-N2719
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Others
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Others
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6-O-Benzoylphlorigidoside B is a Iridoids product that can be isolated from the herbs of Callicarpa formosana .
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- HY-N0993
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Others
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Others
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1,6,8-Trideoxyshanzhigenin is a Iridoids product that can be isolated from the herbs of Gardenia jasminoides .
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- HY-N3932
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Others
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Others
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Garjasmin (compound 1) is a kind of iridoid aglycone. Garjasmin can be isolated from the flowers of Gardenia jasminoides Ellis .
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- HY-N2642
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Others
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Others
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4'-O-trans-p-Coumaroylmussaenoside is a Iridoids product that can be isolated from the leaves of Callicarpa bodinieri. .
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- HY-N2729
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Others
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Others
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6-O-trans-Cinnamoylphlorigidoside B is a Iridoids product that can be isolated from the herbs of Callicarpa nudiflora .
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- HY-N4198
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Others
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Others
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1'''-O-β-D-Glucopyranosylformoside is a Iridoids product that can be isolated from the leaves of Turpinia arguta .
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- HY-N7370
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Others
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Others
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Hybridaphniphylline B is a Daphniphyllum alkaloid and iridoid hybrid. Hybridaphniphylline B can be isolated from stems and leaves of Daphniphyllum longacemosum .
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- HY-N2726
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Others
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Others
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6'-O-p-Hydroxybenzoylcatalposide is a Iridoids product that can be isolated from the leaves of Catalpa ovata G. Don. .
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- HY-N9936
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2''-O-acetylsaikosaponin A
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Others
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Others
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Saikosaponin S5 (2''-O-acetylsaikosaponin A) is a Iridoids product that can be isolated from the barks of Ailanthus integrifolia .
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- HY-17389A
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Others
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Others
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7-Deoxy-10-hydroxyloganetin is a Iridoids product that can be isolated from the seeds of Strychnos nux-vomica .
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- HY-N2764
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Others
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Others
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8,9-Didehydro-7-hydroxydolichodial is a Iridoids product that can be isolated from the herbs of Patrinia villosa. .
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- HY-N9844
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Others
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Others
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Jaspolyanthoside is a trimeric iridoid glycoside can be found in the stems of Jasminum nervosum Lour. (Oleaceae). It lacks anti-inflammatory, antioxidant, and antitumor activities .
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- HY-N8808
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Others
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Others
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10-O-Coumaroyl-10-O-deacetylasperuloside is a Iridoids product that can be isolated from the herbs of Galium aparine L. .
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- HY-N3549
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Bacterial
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Infection
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Catalpin is an iridoid that can be isoalted from Catalpae Fructus.Catalpin shows mutagenic activity towards Salmonella typhimurium strain TA100 .
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- HY-N3408
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Others
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Inflammation/Immunology
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Lamiide, an orally active iridoid compound, can be found in Bouchea fluminensis leaves. Lamiide exhibits anti-inflammatory and anti-lipoperoxidative activity .
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- HY-N0009
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Geniposide
Maximum Cited Publications
19 Publications Verification
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Amyloid-β
Influenza Virus
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Neurological Disease
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Geniposide is an iridoid glucoside extracted from Gardenia jasminoidesEllis fruits; exhibits a varity of biological activities such as anti-diabetic, antioxidative, antiproliferative and neuroprotective activities.
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-
- HY-N18004
-
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Others
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Others
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|
Deacetylasperuloside (Compound 4) is an glycoside found in Hedyotis chrysotricha (Palib) Merr .
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-
- HY-N3229
-
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Others
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Inflammation/Immunology
|
|
Mussaenoside can be isolated from Veronica officinalis L.. Mussaenoside has anti-inflammatory and antioxidant activity .
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-
- HY-N6008
-
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Others
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Others
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|
7-O-Methyl morroniside is an iridoid glycoside (IG) extracted from Cornus officinalis fructus, used in many traditional Chinese medicines .
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-
- HY-N2731
-
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Others
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Others
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|
6-O-Vanilloylajugol is a Iridoids product that can be isolated from the herbs of Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey. .
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-
- HY-N2716
-
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Others
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Others
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|
6-O-(3'',4''-Dimethoxycinnamoyl)catalpol is a Iridoids product that can be isolated from the herbs of Buddleja asiatica Lour .
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-
- HY-N2722
-
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Others
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Others
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|
6-O-Cinnamoylcatalpol is a Iridoids product that can be isolated from the herbs of Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey .
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-
- HY-N17920A
-
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Others
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Neurological Disease
|
|
6β-Methoxygeniposide is a geniposide-type iridoid compound. 6β-Methoxygeniposide induces neurite outgrowth in PC12h cells .
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-
- HY-N8174
-
|
|
NO Synthase
|
Inflammation/Immunology
Cancer
|
|
Valeriandoid F is an iridoid, which potently inhibits NO production with an IC50 value of 0.88 μM. Valeriandoid F has anti-inflammatory and antiproliferative activities .
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-
- HY-N2608
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Others
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Metabolic Disease
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|
7-O-Ethylmorroniside is a iridoid glucoside from the fruit of Cornus officinalis which is a traditional medicine in China and used for the reserch of kidney diseases, including diabetic nephropathy .
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- HY-N2015R
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Reference Standards
Others
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Neurological Disease
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|
Hastatoside (Standard) is the analytical standard of Hastatoside. This product is intended for research and analytical applications. Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep .
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-
- HY-N18784
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Others
|
Neurological Disease
|
|
Valeriana wallichii extract is rich in various bioactive compounds, such as volatile oils, iridoids, alkaloids, flavonoids, and gamma-aminobutyric acid (GABA). Valeriana wallichii extract has sedative and tranquilizing effects.
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-
- HY-N1382
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-
- HY-N0412R
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Reference Standards
Others
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Inflammation/Immunology
|
|
Sesamoside (Standard) is the analytical standard of Sesamoside. This product is intended for research and analytical applications. Sesamoside is a iridoid isolated from the aerial part of? Lamiophlomis rotata. Sesamoside has antiodant and antiglycation activities .
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-
- HY-126407
-
|
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Bacterial
|
Infection
|
|
Secologanin dimethyl acetal (Compound Ⅱ) is an iridoid glucoside that can be isolated from Pterocephalus perennis. Secologanin dimethyl acetal shows antimicrobial activity against S.aureus and S.epidermidi .
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-
- HY-N0494
-
|
Gentiopicrin
|
Cytochrome P450
HCV
|
Inflammation/Immunology
|
|
Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.
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-
- HY-N0409R
-
|
|
Reference Standards
Others
|
Inflammation/Immunology
|
|
Picroside III (Standard) is the analytical standard of Picroside III. This product is intended for research and analytical applications. Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .
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-
- HY-N17690
-
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|
Drug Intermediate
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Others
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|
7-Ketologanic acid is an iridoid glucoside. 7-Ketologanic acid is an efficient precursor for 8-epi-kingisidic acid. 7-Ketologanic acid can be extracted from dry leaves of P. azorica .
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-
- HY-N1503R
-
|
6α-Hydroxygeniposide (Standard); Deacetylasperulosidic acid methyl ester (Standard)
|
Reference Standards
Others
|
Metabolic Disease
|
|
Methyl deacetylasperulosidate (Standard) is the analytical standard of Methyl deacetylasperulosidate. This product is intended for research and analytical applications. Methyl deacetylasperulosidate is an iridoid and shows purgative effects in mice and lowers the blood glucose level in normal mice .
|
-
- HY-N2094
-
|
Genipin 1-gentiobioside; Genipin 1-β-gentiobioside; Genipin gentiobioside
|
Others
|
Inflammation/Immunology
|
|
Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.
|
-
- HY-N18760
-
|
|
Bacterial
|
Infection
Inflammation/Immunology
|
|
Vitex negundo extract is rich in bioactive compounds such as alkaloids, flavonoids, glycosides, volatile oils, triterpenoids, tannins, polyphenols, flavonoids, and iridoid glycosides. Vitex negundo extract possesses anti-inflammatory, antioxidant, antibacterial, and detoxifying properties.
|
-
- HY-N2094R
-
|
Genipin 1-gentiobioside (Standard); Genipin 1-β-gentiobioside (Standard); Genipin gentiobioside (Standard)
|
Reference Standards
Others
|
Inflammation/Immunology
|
|
Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.
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-
- HY-N3302
-
|
(4β)-23-Hydroxyolean-12-ene-3,22-dione
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Others
|
Others
|
|
Melilotigenin B ((4β)-23-Hydroxyolean-12-ene-3,22-dione) is a Iridoids product that can be isolated from the roots of Scrophularia ningpoensis .
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-
- HY-N0009R
-
|
|
Reference Standards
Amyloid-β
Influenza Virus
|
Neurological Disease
|
|
Geniposide (Standard) is the analytical standard of Geniposide. This product is intended for research and analytical applications. Geniposide is an iridoid glucoside extracted from Gardenia jasminoidesEllis fruits; exhibits a varity of biological activities such as anti-diabetic, antioxidative, antiproliferative and neuroprotective activities.
|
-
- HY-B0813R
-
|
UT-15C (Standard)
|
Reference Standards
Prostaglandin Receptor
|
Endocrinology
|
|
Geniposide (Standard) is the analytical standard of Geniposide. This product is intended for research and analytical applications. Geniposide is an iridoid glucoside extracted from Gardenia jasminoidesEllis fruits; exhibits a varity of biological activities such as anti-diabetic, antioxidative, antiproliferative and neuroprotective activities.
|
-
- HY-N2674
-
|
5-Hydroxy-1-methoxyxanthen-9-one
|
Others
|
Others
|
|
5-Hydroxy-1-methoxyxanthone (5-Hydroxy-1-methoxyxanthen-9-one) is a Iridoids product that can be isolated from the roots of Lamiophlomis rotata (Benth.) Kudo .
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-
- HY-N0807R
-
-
- HY-N5070
-
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Depressin
|
Biochemical Assay Reagents
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Others
|
|
Depressine is an iridoid glycoside that can be isolated from the methanol extract of the aerial parts of Gentiana depressa. Depressine can be used to reduce oxidative DNA base damage and strand breaks that are prone to occur during the preparation of silver nanoparticles (AgNPs) .
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-
- HY-W653779
-
|
|
Drug Derivative
|
Others
|
|
8-Oxogeranial is a monoterpene. The terpenoid is produced by 8-hydroxygeraniol dehydrogenase which uses 8-hydroxygeraniol as its substrate. 8-Oxogeranial is itself a substrate for iridoid synthase which synthesizes cis-trans-iridodial and cis-trans-nepetalactol.
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-
- HY-N1382R
-
|
|
Reference Standards
NO Synthase
|
Metabolic Disease
Inflammation/Immunology
|
|
Asperuloside (Standard) is the analytical standard of Asperuloside. This product is intended for research and analytical applications. Asperuloside is an iridoid isolated from Hedyotis diffusa, with anti-inflammatory activity. Asperuloside inhibits inducible nitric oxide synthase (iNOS), suppresses NF-κB and MAPK signaling pathways .
|
-
- HY-N0758
-
|
8-O-Acetyl shanzhiside methyl ester
|
Caspase
NF-κB
|
Inflammation/Immunology
|
|
Barlerin (8-O-Acetyl shanzhiside methyl ester) is an iridoid glucoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang. Barlerin (8-O-Acetyl shanzhiside methyl ester) could inhibt NF-κB.
|
-
- HY-N0494R
-
|
Gentiopicrin (Standard)
|
Reference Standards
Cytochrome P450
HCV
|
Inflammation/Immunology
|
|
Gentiopicroside (Standard) is the analytical standard of Gentiopicroside. This product is intended for research and analytical applications. Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.
|
-
- HY-N12580
-
|
|
Others
|
Metabolic Disease
|
|
Mussaenosidic acid is an active product that can be extracted from Pedicularis kerneri Dalla Torre. Mussaenosidic acid shows weak antiglycation activity .
|
-
- HY-N3552
-
|
|
NF-κB
|
Inflammation/Immunology
|
|
Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages .
|
-
- HY-N11457
-
|
|
Others
|
Others
|
|
Swertiaside is a natural product, that can be isolated from Swertia mussotii Franch .
|
-
- HY-N0758R
-
|
8-O-Acetyl shanzhiside methyl ester (Standard)
|
Caspase
Reference Standards
NF-κB
|
Inflammation/Immunology
|
|
Barlerin (Standard) is the analytical standard of Barlerin. This product is intended for research and analytical applications. Barlerin (8-O-Acetyl shanzhiside methyl ester) is an iridoid glucoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang. Barlerin (8-O-Acetyl shanzhiside methyl ester) could inhibt NF-κB.
|
-
- HY-N6246
-
|
|
NF-κB
ERK
|
Inflammation/Immunology
Cancer
|
|
Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities .
ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .
|
-
- HY-N12203
-
|
|
Others
|
Others
|
|
5-Deoxypulchelloside I is a magnoside glycoside that can be isolated from the aerial parts of the Lamiaceae plant Eremostachys laciniata .
|
-
- HY-126232
-
|
|
NF-κB
TNF Receptor
IKK
|
Infection
Inflammation/Immunology
|
|
Verproside, a catalpol derivative iridoid glycoside isolated from the genus Pseudolysimachion, represses TNF-α -induced MUC5AC expression by inhibiting NF-κB activation via the IKK/IκB signaling cascade. Verproside has potent anti-inflammatory, antioxidant, antinociceptive and anti-asthmatic activities. Verproside has the potential for the study of chronic obstructive pulmonary disease (COPD) .
|
-
- HY-N0397
-
|
|
Parasite
|
Infection
Inflammation/Immunology
|
|
Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities .
|
-
- HY-182295
-
|
|
Reactive Oxygen Species (ROS)
Apoptosis
MMP
Bacterial
Parasite
|
Cardiovascular Disease
Infection
Neurological Disease
|
|
Negundoside is an iridoid glycoside compound. Negundoside exhibits hepatoprotective effects, reduces ROS, lipid peroxidation and intracellular calcium ion levels, and prevents the decrease of mitochondrial membrane potential (MMP) and apoptosis (apoptosis). Negundoside has neuroprotective effects, improves behavioral deficits, alleviates oxidative damage, and ameliorates cerebral infarction. Negundoside also possesses antibacterial and antiparasitic activities .
|
-
- HY-N3009
-
|
|
Drug Derivative
Apoptosis
Bcl-2 Family
|
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
Secoxyloganin is an orally effective iridoid derivative. Secoxyloganin can be isolated from the flower buds of L. japonica. Secoxyloganin induces Apoptosis by inhibiting the expression of Bcl-2. Secoxyloganin potently inhibits the proliferation of breast cancer cells, while exerting weak activity against normal mammary epithelial cells. Secoxyloganin inhibits the decrease in tail vein blood flow associated with allergic reactions .
|
-
- HY-N0513
-
|
|
Reactive Oxygen Species (ROS)
Phosphatase
NF-κB
Keap1-Nrf2
|
Metabolic Disease
Inflammation/Immunology
|
|
Loganic acid is an iridoid isolated from cornelian cherry fruits. Loganic acid inhibits NF-κB signaling pathway, activates Nrf2 signaling pathway, exhibits anti-inflammatory activity. Loganic acid can modulate diet-induced atherosclerosis and redox status. Loganic acid has strong free radical scavenging activity and remarkable cyto-protective effect against heavy metal mediated toxicity. Loganic acid is orally active .
|
-
- HY-N9731
-
|
|
NF-κB
|
Others
|
|
6-O-p-Hydroxybenzoylglutinoside acts as a selective NF-κB inhibitor that suppresses the transcriptional activity of TNF-α-activated NF-κB (IC50=52.78 μM). 6-O-p-Hydroxybenzoylglutinoside shows no significant inhibitory activity against sEH, AChE, or BChE. 6-O-p-Hydroxybenzoylglutinoside is a caged chlorinated iridoid glycoside identified from the seeds of Catalpa bungei (Manchurian catalpa) .
|
-
- HY-121125
-
|
|
Others
|
Others
|
|
Aucubigenin, the aglycone of the iridoid glycoside aucubin, has been characterized through X-ray diffraction analysis. Its crystal structure reveals monoclinic symmetry with specific conformations adopted by its cyclopentane and pyran rings. The study also determined the absolute configurations of both aucubin and aucubigenin. Significant O-H O hydrogen bonding interactions were observed in the crystal lattices of both compounds, highlighting their structural stability and potential for intermolecular interactions .
|
-
- HY-N6246R
-
|
|
Reference Standards
NF-κB
ERK
|
Inflammation/Immunology
Cancer
|
|
Asperulosidic Acid (Standard) is the analytical standard of Asperulosidic Acid. This product is intended for research and analytical applications. Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities .
ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .
|
-
- HY-N0512
-
Loganin
5 Publications Verification
Loganoside
|
Reactive Oxygen Species (ROS)
TNF Receptor
Interleukin Related
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Loganin is a type of iridoid glycoside compound that possesses anti-inflammatory, antioxidant, and antitumor properties, and offers protective effects against acute lung injury and pulmonary fibrosis. Loganin exerts its protective effects against LPS (HY-D1056)-mediated inflammation and oxidative stress by upregulating the Nrf2/HO-1 signaling pathway, and it reduces neuroinflammation caused by spinal cord injury (SCI) .
|
-
- HY-N0397R
-
|
|
Reference Standards
Parasite
|
Infection
Inflammation/Immunology
|
|
Harpagide (Standard) is the analytical standard of Harpagide. This product is intended for research and analytical applications. Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities .
|
-
- HY-N0513R
-
|
|
Reference Standards
Reactive Oxygen Species (ROS)
Phosphatase
NF-κB
Keap1-Nrf2
|
Metabolic Disease
Inflammation/Immunology
|
|
Loganic acid (Standard) is the analytical standard of Loganic acid. This product is intended for research and analytical applications. Loganic acid is an iridoid isolated from cornelian cherry fruits. Loganic acid inhibits NF-κB signaling pathway, activates Nrf2 signaling pathway, exhibits anti-inflammatory activity. Loganic acid can modulate diet-induced atherosclerosis and redox status. Loganic acid has strong free radical scavenging activity and remarkable cyto-protective effect against heavy metal mediated toxicity. Loganic acid is orally active .
|
-
- HY-N0512R
-
|
Loganoside (Standard)
|
Reference Standards
Apoptosis
Keap1-Nrf2
TNF Receptor
Interleukin Related
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Loganin (Standard) is the analytical standard of Loganin. This product is intended for research and analytical applications. Loganin is a type of iridoid glycoside compound that possesses anti-inflammatory, antioxidant, and antitumor properties, and offers protective effects against acute lung injury and pulmonary fibrosis. Loganin exerts its protective effects against LPS (HY-D1056)-mediated inflammation and oxidative stress by upregulating the Nrf2/HO-1 signaling pathway, and it reduces neuroinflammation caused by spinal cord injury (SCI) .
|
-
- HY-N0631
-
|
|
p38 MAPK
NF-κB
JNK
Cholinesterase (ChE)
Acyltransferase
NO Synthase
Interleukin Related
TNF Receptor
Prostaglandin Receptor
ERK
COX
|
Neurological Disease
Inflammation/Immunology
|
|
Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK, JNK, and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity (IC50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS (HY-D1056)-induced inflammatory mediators, including iNOS, COX-2, PGE2, TNF-α, IL-6, and IL-1β, by suppressing NF-κB activation .
|
-
- HY-N0408R
-
|
|
Reference Standards
NF-κB
Reactive Oxygen Species (ROS)
Apoptosis
Influenza Virus
|
Infection
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Picroside II (Standard) is the analytical standard of Picroside II. This product is intended for research and analytical applications. Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti-inflammatory and anti-apoptotic activities.
picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways .
Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury. Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities .
|
-
- HY-N0648
-
|
|
Interleukin Related
Keap1-Nrf2
Heme Oxygenase (HO)
NF-κB
Apoptosis
|
Inflammation/Immunology
|
|
Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin (HY-17394)-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury .
|
-
- HY-N0757
-
|
|
Akt
Bcl-2 Family
Apoptosis
Adrenergic Receptor
|
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
8-O-Acetylharpagide is an orally active iridoid glycoside compound. 8-O-Acetylharpagide exhibits anti-aging activity at low doses and anticancer activity at high doses. 8-O-Acetylharpagide induces late-stage apoptosis and necrosis-like death in cancer cells, and downregulates anti-apoptotic proteins such as Akt, p-Akt and Bcl-2. 8-O-Acetylharpagide is mainly metabolized in rats via demethylation, hydrolysis and glucuronidation, and its active metabolites downregulate the AKT/NF-κB/MMP9 signaling axis. 8-O-Acetylharpagide exerts vasoconstrictive effects by activating vascular α-adrenoceptor .
|
-
- HY-N0631R
-
|
|
Reference Standards
Prostaglandin Receptor
ERK
p38 MAPK
Acyltransferase
TNF Receptor
COX
Cholinesterase (ChE)
Interleukin Related
JNK
NO Synthase
NF-κB
|
Neurological Disease
Inflammation/Immunology
|
|
Cornuside (Standard) is the analytical standard of Cornuside (HY-N0631). This product is intended for research and analytical applications. Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK, JNK, and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity (IC50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS (HY-D1056)-induced inflammatory mediators, including iNOS, COX-2, PGE2, TNF-α, IL-6, and IL-1β, by suppressing NF-κB activation.
|
-
- HY-N0757R
-
|
|
Reference Standards
Akt
Bcl-2 Family
Apoptosis
Adrenergic Receptor
|
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
8-O-Acetylharpagide (Standard) is the analytical standard of 8-O-Acetylharpagide. This product is intended for research and analytical applications. 8-O-Acetylharpagide is an iridoid glycoside compound. 8-O-Acetylharpagide exhibits anti-aging activity at low doses and anticancer activity at high doses. 8-O-Acetylharpagide induces late-stage apoptosis and necrosis-like death in cancer cells, and downregulates anti-apoptotic proteins such as Akt, p-Akt and Bcl-2. 8-O-Acetylharpagide is mainly metabolized in rats via demethylation, hydrolysis and glucuronidation, and its active metabolites downregulate the AKT/NF-κB/MMP9 signaling axis. 8-O-Acetylharpagide exerts vasoconstrictive effects by activating vascular α-adrenoceptor.
|
-
- HY-N0648R
-
|
|
Reference Standards
Interleukin Related
Heme Oxygenase (HO)
Keap1-Nrf2
NF-κB
Apoptosis
|
Inflammation/Immunology
|
|
Monotropein (Standard) is the analytical standard of Monotropein. This product is intended for research and analytical applications. Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin (HY-17394)-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury .
|
-
- HY-N0806
-
|
|
Keap1-Nrf2
AMPK
Sirtuin
NF-κB
NOD-like Receptor (NLR)
Pyroptosis
Apoptosis
Autophagy
PARP
|
Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Sweroside is an iridoid glycoside that targets multiple targets, including the Keap1/Nrf2 axis, NLRP3 inflammasome, SIRT1, NF-κB, AMPK/mTOR pathway, and caspase family. Sweroside promotes Nrf2 nuclear translocation by competitively binding to Keap1. Sweroside also inhibits oxidative stress and NLRP3-mediated pyroptosis by activating Nrf2, inhibits NF-κB inflammatory pathway by activating SIRT1, and promotes autophagy and induces caspase-dependent apoptosis via the AMPK/mTOR pathway. Sweroside has antioxidant, anti-inflammatory, anti-apoptotic, and lipid metabolism regulating activities, and can be used in the research of myocardial ischemia-reperfusion injury, leukemia, acute lung injury, non-alcoholic fatty liver disease, and other fields .
|
-
- HY-N0806R
-
|
|
Reference Standards
Keap1-Nrf2
AMPK
Sirtuin
NF-κB
NOD-like Receptor (NLR)
Pyroptosis
Apoptosis
Autophagy
PARP
|
Metabolic Disease
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Sweroside (Standard) is the analytical standard of Sweroside (HY-N0806). This product is intended for research and analytical applications. Sweroside is an iridoid glycoside that targets multiple targets, including the Keap1/Nrf2 axis, NLRP3 inflammasome, SIRT1, NF-κB, AMPK/mTOR pathway, and caspase family. Sweroside promotes Nrf2 nuclear translocation by competitively binding to Keap1. Sweroside also inhibits oxidative stress and NLRP3-mediated pyroptosis by activating Nrf2, inhibits NF-κB inflammatory pathway by activating SIRT1, and promotes autophagy and induces caspase-dependent apoptosis via the AMPK/mTOR pathway. Sweroside has antioxidant, anti-inflammatory, anti-apoptotic, and lipid metabolism regulating activities, and can be used in the research of myocardial ischemia-reperfusion injury, leukemia, acute lung injury, non-alcoholic fatty liver disease, and other fields .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N0820
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-
-
- HY-N0664
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-
-
- HY-125598
-
-
-
- HY-N0914
-
-
-
- HY-N2015
-
-
-
- HY-N1503
-
-
-
- HY-N8314
-
-
-
- HY-N2772
-
-
-
- HY-N5086
-
-
-
- HY-N0664R
-
|
|
Structural Classification
Eucommia ulmoides Oliver
Iridoids
Terpenoids
Eucommiaceae
Plants
Source Classification
|
Reference Standards
Bacterial
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Aucubin (Standard) is the analytical standard of Aucubin. This product is intended for research and analytical applications. Aucubin, an iridoid glucoside, is isolated from Plantago asiatica, Eucommia ulmoides, the leaves of Aucuba japonica and more recently from butterfly larva. Aucubin has many biological activities, such as antioxidant, anti-aging, anti-inflammatory, antimicrobial, anti-fibrotic, anti-cancer, hepatoprotective, neuroprotective and osteoprotective effects .
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-
- HY-N2400
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-
-
- HY-N0409
-
-
-
- HY-N8046
-
-
-
- HY-N9352
-
-
-
- HY-N4092
-
-
-
- HY-N10590
-
-
-
- HY-N4306
-
-
-
- HY-N1155
-
-
-
- HY-N16570
-
-
-
- HY-N12840
-
-
-
- HY-N4120
-
-
-
- HY-N0820R
-
-
-
- HY-N3030
-
-
-
- HY-N0916
-
-
-
- HY-N6245
-
-
-
- HY-N16596
-
-
-
- HY-N2712
-
-
-
- HY-N12202
-
-
-
- HY-N4092R
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-
-
- HY-124881
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-
-
- HY-N1206
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-
-
- HY-N8759
-
-
-
- HY-N11794
-
-
-
- HY-133109
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-
-
- HY-W750451
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-
-
- HY-133800
-
-
-
- HY-N0914R
-
-
-
- HY-160121
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-
-
- HY-N11659
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-
-
- HY-N13109
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-
-
- HY-N4001
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-
-
- HY-N3978
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-
-
- HY-N9007
-
-
-
- HY-N3948
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-
-
- HY-N3959
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-
-
- HY-N8586
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-
-
- HY-N8972
-
-
-
- HY-N8992
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-
-
- HY-N9293
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-
-
- HY-N7342
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-
- HY-133198
-
-
- HY-N3791
-
-
- HY-N9346
-
-
- HY-N1277
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-
- HY-N1893
-
-
- HY-N4221
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-
- HY-N2839
-
-
- HY-N3839
-
-
- HY-N17947
-
-
- HY-N11712
-
-
- HY-N17900
-
-
- HY-N17922
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-
- HY-N19759
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-
- HY-N17667
-
-
- HY-N19779
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-
- HY-N2730
-
-
- HY-N17840
-
-
- HY-N17467
-
-
- HY-N18043
-
-
- HY-N17920
-
-
- HY-N9817
-
-
- HY-N17065
-
-
- HY-N17113
-
-
- HY-N17090
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-
- HY-W748495
-
-
- HY-N13796
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-
- HY-N17036
-
-
- HY-N7566
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-
- HY-125543
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-
- HY-N13331
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-
- HY-N1211
-
-
- HY-N2955
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-
- HY-N9733
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-
- HY-N17038
-
-
- HY-N0965
-
-
- HY-N2966
-
-
- HY-N3881
-
-
- HY-N18704
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-
- HY-N9178
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-
- HY-N2711
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-
- HY-N9008
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-
- HY-N1124
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-
- HY-N1585
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-
- HY-N2928
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-
- HY-N3080
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-
- HY-N2710
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-
- HY-N1642
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-
- HY-N1008
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-
- HY-N2719
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-
- HY-N0993
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-
- HY-N3932
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-
- HY-N2642
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-
- HY-N2729
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-
- HY-N4198
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-
- HY-N7370
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-
- HY-N2726
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-
- HY-N9936
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-
- HY-17389A
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-
- HY-N2764
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-
- HY-N9844
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-
- HY-N8808
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-
- HY-N3549
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-
- HY-N3408
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-
- HY-N0009
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-
- HY-N18004
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-
- HY-N3229
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-
- HY-N6008
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-
- HY-N2731
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-
- HY-N2716
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-
- HY-N2722
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-
- HY-N17920A
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-
- HY-N8174
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-
- HY-N2608
-
-
- HY-N2015R
-
-
- HY-N18784
-
|
|
Structural Classification
Extract
|
Others
|
|
Valeriana wallichii extract is rich in various bioactive compounds, such as volatile oils, iridoids, alkaloids, flavonoids, and gamma-aminobutyric acid (GABA). Valeriana wallichii extract has sedative and tranquilizing effects.
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- HY-N1382
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-
- HY-N0412R
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-
- HY-126407
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-
- HY-N0494
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-
- HY-N0409R
-
-
- HY-N17690
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-
- HY-N1503R
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-
- HY-N2094
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-
- HY-N18760
-
|
|
Structural Classification
Extract
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Bacterial
|
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Vitex negundo extract is rich in bioactive compounds such as alkaloids, flavonoids, glycosides, volatile oils, triterpenoids, tannins, polyphenols, flavonoids, and iridoid glycosides. Vitex negundo extract possesses anti-inflammatory, antioxidant, antibacterial, and detoxifying properties.
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- HY-N2094R
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-
- HY-N3302
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-
- HY-N0009R
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-
- HY-N2674
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-
- HY-N0807R
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-
- HY-N5070
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-
- HY-N1382R
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-
- HY-N0758
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-
- HY-N0494R
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-
- HY-N12580
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-
- HY-N3552
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-
- HY-N11457
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-
- HY-N0758R
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-
- HY-N6246
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-
- HY-N12203
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-
- HY-126232
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-
- HY-N0397
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-
- HY-N3009
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-
- HY-N0513
-
-
- HY-N9731
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-
- HY-121125
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-
- HY-N6246R
-
|
|
Structural Classification
Iridoids
Terpenoids
Rubiaceae
Plants
Morinda officinalis How
Source Classification
|
Reference Standards
NF-κB
ERK
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Asperulosidic Acid (Standard) is the analytical standard of Asperulosidic Acid. This product is intended for research and analytical applications. Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities .
ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .
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- HY-N0512
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-
- HY-N0397R
-
|
|
Iridoids
Scrophularia ningpoensis Hemsl.
Terpenoids
Scrophulariaceae
Plants
Source Classification
|
Reference Standards
Parasite
|
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Harpagide (Standard) is the analytical standard of Harpagide. This product is intended for research and analytical applications. Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities .
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- HY-N0513R
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-
- HY-N0512R
-
-
- HY-N0631
-
|
|
Structural Classification
Iridoids
Cornaceae
Classification of Application Fields
Cornus officinalis Sieb. et Zucc.
Terpenoids
Phenols
Polyphenols
Plants
Inflammation/Immunology
Disease Research Fields
Source Classification
|
p38 MAPK
NF-κB
JNK
Cholinesterase (ChE)
Acyltransferase
NO Synthase
Interleukin Related
TNF Receptor
Prostaglandin Receptor
ERK
COX
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Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK, JNK, and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity (IC50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS (HY-D1056)-induced inflammatory mediators, including iNOS, COX-2, PGE2, TNF-α, IL-6, and IL-1β, by suppressing NF-κB activation .
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- HY-N0408R
-
|
|
Structural Classification
Iridoids
Terpenoids
Scrophulariaceae
Plants
Picrorhiza scrophulariiflora Pennell
|
Reference Standards
NF-κB
Reactive Oxygen Species (ROS)
Apoptosis
Influenza Virus
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Picroside II (Standard) is the analytical standard of Picroside II. This product is intended for research and analytical applications. Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti-inflammatory and anti-apoptotic activities.
picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways .
Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury. Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities .
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- HY-N0648
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-
- HY-N0757
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-
- HY-N0631R
-
|
|
Structural Classification
Iridoids
Cornaceae
Cornus officinalis Sieb. et Zucc.
Terpenoids
Phenols
Polyphenols
Plants
Source Classification
|
Reference Standards
Prostaglandin Receptor
ERK
p38 MAPK
Acyltransferase
TNF Receptor
COX
Cholinesterase (ChE)
Interleukin Related
JNK
NO Synthase
NF-κB
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Cornuside (Standard) is the analytical standard of Cornuside (HY-N0631). This product is intended for research and analytical applications. Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK, JNK, and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity (IC50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS (HY-D1056)-induced inflammatory mediators, including iNOS, COX-2, PGE2, TNF-α, IL-6, and IL-1β, by suppressing NF-κB activation.
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- HY-N0757R
-
|
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Structural Classification
other families
Iridoids
Terpenoids
Plants
Source Classification
|
Reference Standards
Akt
Bcl-2 Family
Apoptosis
Adrenergic Receptor
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8-O-Acetylharpagide (Standard) is the analytical standard of 8-O-Acetylharpagide. This product is intended for research and analytical applications. 8-O-Acetylharpagide is an iridoid glycoside compound. 8-O-Acetylharpagide exhibits anti-aging activity at low doses and anticancer activity at high doses. 8-O-Acetylharpagide induces late-stage apoptosis and necrosis-like death in cancer cells, and downregulates anti-apoptotic proteins such as Akt, p-Akt and Bcl-2. 8-O-Acetylharpagide is mainly metabolized in rats via demethylation, hydrolysis and glucuronidation, and its active metabolites downregulate the AKT/NF-κB/MMP9 signaling axis. 8-O-Acetylharpagide exerts vasoconstrictive effects by activating vascular α-adrenoceptor.
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- HY-N0648R
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-
- HY-N0806
-
|
|
Monophenols
Classification of Application Fields
Labiatae
Lespedeza tomentosa (Thunb.) Siebold ex Maxim.
Phenols
Metabolic Disease
Plants
Disease Research Fields
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Keap1-Nrf2
AMPK
Sirtuin
NF-κB
NOD-like Receptor (NLR)
Pyroptosis
Apoptosis
Autophagy
PARP
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Sweroside is an iridoid glycoside that targets multiple targets, including the Keap1/Nrf2 axis, NLRP3 inflammasome, SIRT1, NF-κB, AMPK/mTOR pathway, and caspase family. Sweroside promotes Nrf2 nuclear translocation by competitively binding to Keap1. Sweroside also inhibits oxidative stress and NLRP3-mediated pyroptosis by activating Nrf2, inhibits NF-κB inflammatory pathway by activating SIRT1, and promotes autophagy and induces caspase-dependent apoptosis via the AMPK/mTOR pathway. Sweroside has antioxidant, anti-inflammatory, anti-apoptotic, and lipid metabolism regulating activities, and can be used in the research of myocardial ischemia-reperfusion injury, leukemia, acute lung injury, non-alcoholic fatty liver disease, and other fields .
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- HY-N0806R
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|
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Structural Classification
Monophenols
Labiatae
Lespedeza tomentosa (Thunb.) Siebold ex Maxim.
Phenols
Plants
|
Reference Standards
Keap1-Nrf2
AMPK
Sirtuin
NF-κB
NOD-like Receptor (NLR)
Pyroptosis
Apoptosis
Autophagy
PARP
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Sweroside (Standard) is the analytical standard of Sweroside (HY-N0806). This product is intended for research and analytical applications. Sweroside is an iridoid glycoside that targets multiple targets, including the Keap1/Nrf2 axis, NLRP3 inflammasome, SIRT1, NF-κB, AMPK/mTOR pathway, and caspase family. Sweroside promotes Nrf2 nuclear translocation by competitively binding to Keap1. Sweroside also inhibits oxidative stress and NLRP3-mediated pyroptosis by activating Nrf2, inhibits NF-κB inflammatory pathway by activating SIRT1, and promotes autophagy and induces caspase-dependent apoptosis via the AMPK/mTOR pathway. Sweroside has antioxidant, anti-inflammatory, anti-apoptotic, and lipid metabolism regulating activities, and can be used in the research of myocardial ischemia-reperfusion injury, leukemia, acute lung injury, non-alcoholic fatty liver disease, and other fields .
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