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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
kat6a+inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "kat6a+inhibitor" in MCE Product Catalog:
15
15 Publications Verification
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WM-1119, a chemical probe, is a highly potent and selective KAT6A inhibitor, with an IC50 of 0.25 μM for KAT6A in lymphoma cells, the binding KD values of WM-1119 with KAT6A, KAT5 and KAT7 are 2 nM, 2.2 μM, 0.5 μM , respectively .
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PF-9363 (CTx-648) is a first-in-class potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer .
1
1 Cited Publications
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CTX-0124143 is a KAT6A inhibitor with a sulfonyl hydrazine skeleton .
Synonyms: PF-07248144
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Prifetrastat (PF-07248144), a first-in-class, selective, and orally active KAT6A and KAT6AB inhibitor. Prifetrastat can be used for the study of ER+/HER2− breast cancer .
Cat. No.: HY-159957
CAS No.: 2520347-03-7
BAY-184 is a selective and orally active KAT6A and KAT6B inhibitor. BAY-184 inhibits KAT6A/KAT6B activity with an IC50 of 71 nM and 83 nM. respectively BAY-184 inhibits ERα transcriptional activity. BAY-184 inhibits proliferation of diverse breast cancer subtypes, and inhibits tumor growth .
Cat. No.: HY-162994
CAS No.: 2991087-72-8
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KAT6A-IN-1 is a KAT6A inhibitor with an IC50 of <10 μM. KAT6A-IN-1 can be used for the research of cancer .
Cat. No.: HY-162995
CAS No.: 2991087-74-0
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KAT6A-IN-2 (compund 7) is a KAT6A inhibitor .
Cat. No.: HY-102058R
CAS No.: 2055397-28-7
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WM-1119 (Standard) is the analytical standard of WM-1119 (HY-102058). This product is intended for research and analytical applications. WM-1119, a chemical probe, is a highly potent and selective KAT6A inhibitor, with an IC50 of 0.25 μM for KAT6A in lymphoma cells, the binding Kd values of WM-1119 with KAT6A, KAT5 and KAT7 are 2 nM, 2.2 μM, 0.5 μM , respectively .
Cat. No.: HY-187466
CAS No.: 3068205-08-0
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KAT6A/B-IN-1 is a KAT6A/KAT6B inhibitor (IC50 = 3.2 nM and 25.2 nM) that inhibits lysine acetyltransferase activity. KAT6A/B-IN-1 inhibits cancer cell proliferation and tumor growth in xenograft models. KAT6A/B-IN-1 exhibits chemical and physical stability, low hygroscopicity, and reduced sensitivity to heat, humidity, and light. KAT6A/B-IN-1 is used in the study of breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
