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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
mTOR inhibitor-1
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "mTOR inhibitor-1" in MCE Product Catalog:
3
1
1 Cited Publications
HDACs/mTOR Inhibitor 1 is a dual HDACs and mTOR inhibitor, with IC50s of 0.19 nM, 1.8 nM, 1.2 nM for HDAC1, HDAC6, mTOR, respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induces tumor cell apoptosis with low toxicity in vivo. HDACs/mTOR Inhibitor 1 can be used in the research of hematologic malignancies .
Cat. No.: HY-158039
Purity: 99.87%
Target:
Research Areas:
YCH2823 is an inhibitor of USP7 (IC50 = 49.6 nM; Kd = 0.117 μM). YCH2823 shows significant efficacy in inhibiting TP53 wild-type and mutant tumors, with approximately 5-fold higher potency than FT671. YCH2823 induce apoptosis. YCH2823 synergistic effects with mTOR inhibitors .
Cat. No.: HY-112614
CAS No.: 2135639-94-8
ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibitor, with an IC50 of 0.7 nM, shows weak activity against mTOR (IC50, 21 μM), DNAPK (IC50, 2.8 μM), PI3Kα (IC50, 3.8 μM), PI3Kβ (IC50, 10.3 μM), PI3Kγ (IC50, 3 μM) and PI3Kδ (IC50, 0.73 μM). ATM Inhibitor-1 exhibits anti-tumor activity .
Cat. No.: HY-101776A
Purity: 98.63%
Synonyms: Desmethyl-SB2343 hydrochloride
Desmethyl-VS-5584 hydrochloride is a dimethyl analog of VS-5584, a potent and selective mTOR/< with a pyridine[2,3-d]pyrimidine structure. b>PI3KDual inhibitor .
Cat. No.: HY-150061
CAS No.: 853910-61-9
NVP-BBD130 is a potent, stable, ATP-competitive and orally active dual PI3K and mTOR inhibitor . NVP-BBD130 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-W003943
CAS No.: 903899-13-8
Target:
Research Areas:
6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block, which can be used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B). 6-Hydroxypyridin-3-ylboronic acid has also been used in the synthesis of mammalian target of rapamycin (mTOR) inhibitors .
Cat. No.: HY-W780189
CAS No.: 851976-50-6
Synonyms: (rac)-AAD1566; (rac)-NUZ-001
(rac)-Monepantel ((rac)-AAD1566) is the racemic form of Monepantel (HY-14774). Monepantel (AAD1566, NUZ-001), an antiparasitic agent, is an orally active mTOR inhibitor .
Cat. No.: HY-176947
CAS No.: 1887095-85-3
Target:
Research Areas:
Demethyl-sapanisertib-C2-amide-PEG7-C2-N3 (Compound 10c) is an azide group linker used for coupling, which can be employed in the synthesis of "Rapa-Link" compounds, such as M-1111 (HY-176948), an mTOR inhibitor .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
