1949802-49-6

PI3K/mTOR Inhibitor-1 Chemical Structure
1949802-49-6

Chemical Structure

PI3K/mTOR Inhibitor-1

  • CAS No.: 1949802-49-6
  • Formula:C18H22FN5O3S
  • Molecular Weight:407.46

IUPAC Name: (S)-4-fluoro-5-(2-(3-methylmorpholino)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)pyridin-2-amine

InChIKey: LBIPJQHFIZPQHA-NSHDSACASA-N

SMILES: NC1=CC(F)=C(C2=CC(C3(CC3)S(=O)(C)=O)=NC(N4[C@@H](C)COCC4)=N2)C=N1

Biological Activity: PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual PI3K/mTOR inhibitor with IC50s of 20/376/204/46 nM and 186 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ and mTOR, respectively[1]. Antitumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-112602 		PI3K/mTOR Inhibitor-1 PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual PI3K/mTOR inhibitor with IC50s of 20/376/204/46 nM and 186 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ and mTOR, respectively. Antitumor activity.
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