2 Results for "

macrocyclic diamine

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "macrocyclic diamine" in MCE Product Catalog:

Cat. No.: HY-159650
CAS No.: 2724937-55-5
Target:  

Adenosine Receptor

Research Areas:  

Cancer

EOS-984 is a macrocyclic diamine equilibrative nucleoside transporter 1 (ENT1) inhibitor. EOS984 inhibits ENT1 and ENT1-mediated nucleoside transport, restricting adenosine entry into cells via ENT1, thereby attenuating ATP-derived adenosine-mediated T cell immunosuppression and restoring primary human T cell proliferation. EOS984 can be used in research related to ENT1-mediated nucleoside transport, adenosine-related immunosuppression, and tumor immunity .
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Cat. No.: HY-P12216
CAS No.: 3115127-25-5
Target:  

Drug Intermediate

Research Areas:  

Metabolic Disease

Enlicitide northern fragment 4 is a key intermediate obtained via the retrosynthetic disconnection of Enlicitide decanoate (HY-W1126955). Enlicitide northern fragment 4 participates in the protecting-group-free biocatalytic convergent assembly of Enlicitide decanoate, an oral macrocyclic peptide PCSK9 inhibitor. Enlicitide northern fragment 4 can be used for the synthesis of Enlicitide decanoate, thereby supporting research related to hypercholesterolemia .
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