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matrix metalloproteinase-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	MMP (4) Apoptosis (1) Caspase (1) CDK (2) Collagen (1) DNA/RNA Synthesis (1) p38 MAPK (1) PGE synthase (1) PI3K (2) PKC (2) PPAR (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) TGF-β Receptor (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Inflammation/Immunology (2) Metabolic Disease (1)

7

Inhibitors & Agonists

1

Fluorescent Dyes

2

Peptides

3

Natural
Products

3

Recombinant Proteins

3

Antibodies

Targets Recommended: MMP ADAMTS

Cat. No.	상품명	Target	연구분야	Chemical Structure

Desmethylglycitein 3 Publications Verification 4',6,7-Trihydroxyisoflavone	CDK PI3K PKC	Cancer
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .

Porphyra 334	Reactive Oxygen Species (ROS) MMP Collagen PPAR DNA/RNA Synthesis Apoptosis Caspase	Metabolic Disease Inflammation/Immunology
Porphyra 334 is a carnosine-like amino acid and a natural photoprotective agent and antioxidant. Porphyra-334 exerts its photoprotective effects by scavenging ROS, inhibiting the expression and activity of MMP-1/8, and promoting the synthesis of collagen and elastin. Porphyra 334 effectively inhibits linoleic acid oxidation induced by alkyl radicals (AAPH) and singlet oxygen. Porphyra 334 has anti-obesity potential by inhibiting the expression of PPARγ2 and C/EBPα. Porphyra 334 protects cells against UV-induced DNA damage and apoptosis by inhibiting the activation of caspase-3 .

MMP-1 Substrate	MMP	Others
MMP-1 Substrate is a matrix metalloproteinase-1 (MMP-1) selective substrate that can be used for the fluorometric determination of MMP-1 enzymatic activity .

Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2	MMP	Others
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity .

Desmethylglycitein (Standard) 4',6,7-Trihydroxyisoflavone (Standard)	Reference Standards CDK PI3K PKC	Cancer
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .

ALK5-IN-82	TGF-β Receptor	Cardiovascular Disease
ALK5-IN-82 is a potent and selective inhibitor against activin receptor-like kinase 5 (ALK5) with an IC₅₀ value of 9.1 nM. ALK5-IN-82 inhibits the protein expression of α-smooth muscle actin (α-SMA), collagen I and tissue inhibitor of metalloproteinase 1 (TIMP-1)/matrix metalloproteinase 13 (MMP-13) in transforming growth factor-β-induced human umbilical vein endothelial cells. ALK5-IN-82 is promising for research of cardiac fibrosis .

R-130823	p38 MAPK MMP PGE synthase	Inflammation/Immunology
R-130823 is an orally active, highly selective p38α inhibitor with an IC₅₀ of 22 nM against p38α, an IC₅₀ of 820 nM against p38β, and no activity against p38γ or p38δ. R-130823 downregulates downstream cartilage degradation and inflammatory mediators, and inhibits the release of MMP-13, MMP-1 and PGE2. R-130823 reduces hind paw swelling, improves hyperalgesia, and blocks arthritis progression. R-130823 is applicable to research related to osteoarthritis and rheumatoid arthritis .

Cat. No.	상품명	Type

Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2	Fluorescent Dyes
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity .

Cat. No.	상품명	Target	Research Area

MMP-1 Substrate	MMP	Others
MMP-1 Substrate is a matrix metalloproteinase-1 (MMP-1) selective substrate that can be used for the fluorometric determination of MMP-1 enzymatic activity .

Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2	MMP	Others
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity .

Cat. No.	상품명	Category	Target	Chemical Structure

Desmethylglycitein 3 Publications Verification 4',6,7-Trihydroxyisoflavone	Flavonoids Classification of Application Fields Leguminosae Glycine max (L.) merr Phenols Polyphenols Plants Disease Research Fields Isoflavones Source Classification Cancer	CDK PI3K PKC
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .

Porphyra 334	Structural Classification Animals Classification of Application Fields Sunscreen Ketones, Aldehydes, Acids Metabolic Disease Amino acids Cosmetic Research Disease Research Fields Source Classification	Reactive Oxygen Species (ROS) MMP Collagen PPAR DNA/RNA Synthesis Apoptosis Caspase
Porphyra 334 is a carnosine-like amino acid and a natural photoprotective agent and antioxidant. Porphyra-334 exerts its photoprotective effects by scavenging ROS, inhibiting the expression and activity of MMP-1/8, and promoting the synthesis of collagen and elastin. Porphyra 334 effectively inhibits linoleic acid oxidation induced by alkyl radicals (AAPH) and singlet oxygen. Porphyra 334 has anti-obesity potential by inhibiting the expression of PPARγ2 and C/EBPα. Porphyra 334 protects cells against UV-induced DNA damage and apoptosis by inhibiting the activation of caspase-3 .

Desmethylglycitein (Standard) 4',6,7-Trihydroxyisoflavone (Standard)	Structural Classification Flavonoids Leguminosae Glycine max (L.) merr Phenols Polyphenols Plants Isoflavones Source Classification	Reference Standards CDK PI3K PKC
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .

Species:	Human (3)
Tag:	His (3)
Source:	HEK293 (2) E. coli (1)

Cat. No.	Compare	상품명	Species	Source	Image

	MMP-1 Protein, Human (HEK293, His, solution) 1 Publications Verification rHuInterstitial collagenase/MMP-1, His; Interstitial Collagenase; Fibroblast Collagenase; matrix metalloproteinase-1; MMP-1; MMP1; CLG	Human	HEK293
	The MMP-1 protein acts as an enzyme capable of cleaving types I, II, and III collagen at specific sites within the helical domain. In addition, it exhibits lytic activity against type VII and type X collagen. MMP-1 Protein, Human (HEK293, His, solution) is the recombinant human-derived MMP-1 protein, expressed by HEK293 , with C-6*His labeled tag.

	MMP-1 Protein, Human (HEK293, C-His) rHuInterstitial collagenase/MMP-1, His; Interstitial Collagenase; Fibroblast Collagenase; matrix metalloproteinase-1; MMP-1; MMP1; CLG	Human	HEK293
	The MMP-1 protein acts as an enzyme capable of cleaving types I, II, and III collagen at specific sites within the helical domain. In addition, it exhibits lytic activity against type VII and type X collagen. MMP-1 Protein, Human (HEK293, C-His) is the recombinant human-derived MMP-1, expressed by HEK293, with C-6*His labeled tag.

	MMP-14 Protein, Human (C-His) matrix metalloproteinase 14 ; matrix metalloproteinase-14; Membrane type 1 matrix metalloproteinase ; Membrane type 1 metalloprotease; Membrane type matrix metalloproteinase 1; Membrane-type-1 matrix metalloproteinase; MMP 14; MMP X1; MMP-14; MMP-X1; Mmp14; MMP14_HUMAN; MMPX1; MT MMP 1	Human	E. coli
	MMP-14 protein is an endopeptidase that degrades collagen and activates progelatinase A.

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Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
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Endotoxin Level
Biological Activity
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Storage & Stability
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

Host:	Mouse (1) Rabbit (2)
Reactivity:	Human (3)
Application:	IHC-P (1) ICC/IF (1) IP (1) WB (3) FC (1)
Isotype:	IgG (2) IgG2a (1)
Conjugation:	Non-conjugated (3)
Clonality:	Polyclonal (1) Monoclonal (2)
Modification:	Unmodified (3)

Cat. No.	Compare	상품명	Application	Reactivity	Image

	MMP-1 Antibody (YA3394) MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; matrix metalloproteinase-1; MMP-1	WB, FC, ICC/IF, IHC-P	Human
	MMP-1 Antibody (YA3394) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP-1.

	MMP-1 Antibody (YA4972) MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; matrix metalloproteinase-1; MMP-1	WB	Human
	MMP-1 Antibody (YA4972) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MMP-1.

	MMP-1 Antibody MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; matrix metalloproteinase-1; MMP-1	WB, IP	Human
	MMP-1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to MMP-1.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

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