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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
matrix metalloproteinase-1
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "matrix metalloproteinase-1" in MCE Product Catalog:
3
1
1 Cited Publications
Cat. No.: HY-P70250
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP1; matrix Metallopeptidase 1 (Interstitial Collagenase); Prev. CLG; matrix metalloproteinase 1; Interstitial Collagenase; matrix Metalloprotease 1; Fibroblast Collagenase; Alternative Protein MMP1; matrix metalloproteinase 1 (Interstitial Collagenase); MMP-1; matrix Metallopeptidase 1; matrix metalloproteinase-1
Species:
Human
Source:
HEK293
Cat. No.: HY-126956
CAS No.: 70579-26-9
Cat. No.: HY-161169A
CAS No.: 2865106-78-9
TP0628103 TFA is a potent and highly selective MMP-7 inhibitor with an IC50 of 0.17 nM. TP0628103 TFA undergoes structural optimization via molecular isoelectric point shifting, which reduces organic anion transporter (OAT)-mediated clearance, while maintaining potent MMP-7 inhibitory activity and enhancing MMP subtype selectivity. TP0628103 TFA is applicable for research on the regulatory mechanisms of MMP-7-related matrix metalloproteinases .
Cat. No.: HY-P10043
CAS No.: 150956-93-7
Cat. No.: HY-P3098
CAS No.: 256394-94-2
Cat. No.: HY-161169
CAS No.: 2865102-08-3
TP0628103 is a potent and highly selective MMP-7 inhibitor with an IC50 of 0.17 nM. TP0628103 undergoes structural optimization via molecular isoelectric point shifting, which reduces organic anion transporter (OAT)-mediated clearance, while maintaining potent MMP-7 inhibitory activity and enhancing MMP subtype selectivity. TP0628103 is applicable for research on the regulatory mechanisms of MMP-7-related matrix metalloproteinases .
Cat. No.: HY-N5072R
CAS No.: 17817-31-1
Synonyms: 4',6,7-Trihydroxyisoflavone (Standard)
Target:
Cat. No.: HY-P70250A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP1; matrix Metallopeptidase 1 (Interstitial Collagenase); Prev. CLG; matrix metalloproteinase 1; Interstitial Collagenase; matrix Metalloprotease 1; Fibroblast Collagenase; Alternative Protein MMP1; matrix metalloproteinase 1 (Interstitial Collagenase)
Species:
Human
Source:
HEK293
Cat. No.: HY-N7984
CAS No.: 55481-90-8
Synonyms: Laricitrin 3-O-rutinoside
Category:
Cat. No.: HY-162902
CAS No.: 3001361-04-9
Target:
Research Areas:
ALK5-IN-82 is a potent and selective inhibitor against activin receptor-like kinase 5 (ALK5) with an IC50 value of 9.1 nM. ALK5-IN-82 inhibits the protein expression of α-smooth muscle actin (α-SMA), collagen I and tissue inhibitor of metalloproteinase 1 (TIMP-1)/matrix metalloproteinase 13 (MMP-13) in transforming growth factor-β-induced human umbilical vein endothelial cells. ALK5-IN-82 is promising for research of cardiac fibrosis .
Cat. No.: HY-119138
CAS No.: 321344-32-5
Target:
Research Areas:
R-130823 is an orally active, highly selective p38α inhibitor with an IC50 of 22 nM against p38α, an IC50 of 820 nM against p38β, and no activity against p38γ or p38δ. R-130823 downregulates downstream cartilage degradation and inflammatory mediators, and inhibits the release of MMP-13, MMP-1 and PGE2. R-130823 reduces hind paw swelling, improves hyperalgesia, and blocks arthritis progression. R-130823 is applicable to research related to osteoarthritis and rheumatoid arthritis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
