10 Results for "

mature T-cell

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "mature T-cell" in MCE Product Catalog:

Cat. No.: HY-164002
CAS No.: 1609465-78-2
Target:  

Btk

Research Areas:  

Others

PF-303 is a potent, oral inhibitor of Bruton's tyrosine kinase (BTK) (IC50=0.64 nM). The melamine portion of PF-303 forms a covalent bond with BTK's Cys481, which is reversible and exhibits a high selectivity compared to irreversible covalent BTK inhibitors. PF-303 can be used to model and study the effects of BTK inhibition on the mature immune system, including effects on B-cell subsets, antibody responses, and T-cell-mediated activation .
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Cat. No.: HY-A0003BR
CAS No.: 847871-99-2
Synonyms: CC-5013 hemihydrate (Standard)
Lenalidomide (hemihydrate) (Standard) is the analytical standard of Lenalidomide (hemihydrate). This product is intended for research and analytical applications. Lenalidomide hemihydrate (CC-5013 hemihydrate), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells .
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Cat. No.: HY-174766
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CCL17 mRNA encodes the human C-C motif chemokine ligand 17 (CCL17) protein, a cytokine that displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. CCL17 plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
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Cat. No.: HY-P991318

Target:  

Mucin

Research Areas:  

Cancer

AR20.5 is a human monoclonal antibody (mAb) targeting MUC1. AR20.5 increases the number of activated CD8 T cells, CD3+CD4−CD8−(DN) T cells, and mature dendritic cells in pancreatic tumor-bearing mice. AR20.5 can be used in anti-pancreatic cancer immunity research .
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Cat. No.: HY-P992088

Research Areas:  

Inflammation/Immunology

Zolimomab is an anti-human monoclonal antibody targeting-CD5. Zolimomab binds to the CD5 antigen found on mature T-cells. Zolimomab can be used for the research of graft-versus-host disease (GVHD) .
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Cat. No.: HY-P701856
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MTCP1; TCL1 Family AKT Coactivator C; mature T cell Proliferation 1; Protein P13 MTCP-1; P13MTCP1; MTCP-1 Type B1; P8MTCP1; mature T-cell Proliferation 1; TCL1C; C6.1B; mature T-cell Proliferation-1 Type B1
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P701857
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MTCP1; TCL1 Family AKT Coactivator C; mature T cell Proliferation 1; Protein P13 MTCP-1; P13MTCP1; MTCP-1 Type B1; P8MTCP1; mature T-cell Proliferation 1; TCL1C; C6.1B; mature T-cell Proliferation-1 Type B1
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P992275

Target:  

γ-secretase

Research Areas:  

Neurological Disease Cancer

Anti-Nicastrin Antibody (A5226A) is a monoclonal antibody against Nicastrin and an inhibitor of γ-secretase. Anti-Nicastrin Antibody (A5226A) recognizes the fully glycosylated mature presenilin enhancer in the active γ-secretase complex and inhibits its activity via competition for substrate binding. Anti-Nicastrin Antibody (A5226A) abrogates the growth of cancer cells dependent on γ-secretase activity. Anti-Nicastrin Antibody (A5226A) serves as an imaging tool to visualize the endocytic trafficking of active γ-secretase, and also acts as a detection reagent to evaluate the endocytic efficiency of γ-secretase. Anti-Nicastrin Antibody (A5226A) can be used in studies related to non-small cell lung cancer, T-cell acute lymphoblastic leukemia and Alzheimer's disease .
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Cat. No.: HY-P992061

Target:  

CD3 Calcium Channel

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD3E Antibody (500A2) is an antibody targeting mouse CD3ε, which specifically binds to the region on CD3ε adjacent to the T cell receptor binding site. Anti-Mouse CD3E Antibody (500A2) triggers functional signal transduction in immature T cells and activates naive T cells. When cross-linked, Anti-Mouse CD3E Antibody (500A2) induces a rapid, robust and transient increase in cytoplasmic calcium concentration, acting as a potent calcium flux inducer. Anti-Mouse CD3E Antibody (500A2) is suitable for multiple experimental techniques such as flow cytometry, immunoprecipitation and EMARS reactions. It can be used to detect CD3E expression on thymocytes, mature T lymphocytes and NK-T cells from different mouse strains, or to identify membrane cluster components of the TCR complex, and shows no cross-reactivity with rat leukocytes .
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Cat. No.: HY-P992330
Synonyms: KB312

Research Areas:  

Inflammation/Immunology

CBT004 (KB312) is a human IgG1κ type monoclonal antibody against CD83. CD83 is a type I transmembrane glycoprotein and is a highly expressed marker on the surface of mature DCs. It can also be induced to be expressed on activated B cells, some activated T cells, and activated monocytes.
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