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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
microphthalmia-associated transcription factor
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "microphthalmia-associated transcription factor" in MCE Product Catalog:
Target:
Cat. No.: HY-N6901
CAS No.: 56857-57-9
Category:
other families Flavonoids Flavones Metabolic Disease Phenols Polyphenols Plants Disease Research Fields
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Cat. No.: HY-N10623
CAS No.: 2767066-84-0
Category:
Terpenoids Sesquiterpenes Plants Compositae Seriphidium transiliense Disease Research Fields Cancer
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Cat. No.: HY-P4497
CAS No.: 71835-80-8
Cat. No.: HY-179717
Research Areas:
WZS0347 is a MITF PROTAC degrader. WZS0347 effectively reduces MITF protein levels in various melanoma cell lines. WZS0347 induces MITF degradation via the cereblon-dependent ubiquitin-proteasome pathway, downregulates the expression of downstream target genes of MITF, and inhibits the colony formation and migration abilities of cancer cells. WZS0347 can be used in melanoma-related research .
Cat. No.: HY-N3810
CAS No.: 57719-81-0
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Synonyms: trans-10-Pentadecenoic acid
Research Areas:
10 (E)-Pentadecenoic acid (trans-10-Pentadecenoic acid) is a melanin synthesis inhibitor. 10 (E)-Pentadecenoic acid inhibits nuclear translocation and reduces the protein level of phosphorylated microphthalmia-associated transcription factor (MITF), as well as decreases intracellular tyrosinase activity. 10 (E)-Pentadecenoic acid can be used in the research of skin pigmentation disorders .
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Target:
Cat. No.: HY-157010
CAS No.: 1365531-21-0
Target:
Research Areas:
AP736 is a potent tyrosinase inhibitor (IC50 = 0.9 μM) with anti-melanogenesis activity in normal human melanocytes (IC50 = 0.11 μM). AP736 suppresses the expression of tyrosinase and TRP-1/2 by inhibiting the cAMP-PKA-CREB signalling axis, leading to reduced microphthalmia-associated transcription factor (MITF) transcripts and proteins. AP736 can be used for melanogenesis and hyperpigmentation research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
