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monogalactosyldiacylglycerol

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By Targets:	Apoptosis (2) Biochemical Assay Reagents (1) DNA/RNA Synthesis (1) Fluorescent Dye (1) Glycosyltransferase (1) Herbicide (1) Progesterone Receptor (1)
By Research Areas:	Cancer (1)
Oligonucleotides:	Phospholipids (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-115625

AG-205	Progesterone Receptor Apoptosis Glycosyltransferase	Cancer
AG-205 is a progesterone receptor membrane component 1 (PGRMC1) antagonist and CGT inhibitor, with an IC₅₀ of 50 μM against rat CGT. AG-205 exhibits antimitotic, antimigratory and anti-invasive activities. AG-205 increases the expression of genes encoding cholesterol biosynthesis pathway or steroidogenic enzymes. AG-205 promotes the regulation of cell cycle by apoptosis and reduces the migratory and invasive capacities of ovarian and breast cancer cells. AG-205 can be used in research related to renal cancer and breast cancer .

HY-N12540

*Monogalactosyldiacylglycerol* MGDG	DNA/RNA Synthesis Apoptosis	Others
Monogalactosyldiacylglycerol (MGDG) is a galactolipid with anti-inflammatory and anticancer activities, which is found in photosynthetic organisms. Monogalactosyldiacylglycerol is a potent DNA polymerase inhibitor with pro-apoptotic activity. Monogalactosyldiacylglycerol inhibits the synthesis of LPS (HY-D1056)-induced inflammation-related proteins (Ex-FABP, Avidin, Serum Amyloid A). Monogalactosyldiacylglycerol exerts an anti-proliferative effect on chicken articular chondrocytes . Monogalactosyldiacylglycerol can be used in research related to osteoarthritis, cancer and inflammatory diseases .

HY-134174A

*1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium* 16:0-18:1 PA	Biochemical Assay Reagents
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium (16:0-18:1 PA) is a phospholipid with activities in regulating biological membrane fluidity and participating in cell signal transduction. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium can be used to study the effects on the activity of chloroplast envelope monogalactosyldiacylglycerol (MGDG) synthase. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium plays an important role in cell membrane integrity and function.

HY-137798

Chromozym PL	Fluorescent Dye	Others
Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .

HY-N16337

Hydrogenated MGDG	Others	Others
Hydrogenated MGDG is a type of glycolipid. Monogalactosyldiacylglycerol (MGDG), a galactosylglycerolipid, is a major lipid in the thylakoid membrane of the chloroplast of leaves. It is also localized in the roots, fruits and grains. MGDG is synthesized from Monogalactosyldiacylglycerol synthase 1 (MGD1). It is a precursor for digalactosyldiacylglycerol (DGDG).

HY-N9677

Digalactosyldiacylglycerol	Herbicide	Others
Digalactosyldiacylglycerol is a membrane structure stabilizer that selectively acts on photosystem II light-harvesting complex II (LHCII), serving as a natural bilayer-forming lipid in plant thylakoid membranes. Digalactosyldiacylglycerol constructs a lipid bilayer environment with monogalactosyldiacylglycerol (MGDG) in a 2:1 molar ratio, stabilizing the supramolecular structure of LHCII through interactions such as hydrogen bonding. Its core activity is maintaining thylakoid membrane stacking (grana formation) and supporting photosynthesis-related functions, while also possessing functions in light harvesting assistance and excitation energy quenching regulation under light stress. Digalactosyldiacylglycerol can be used in research on plant photosynthesis mechanisms, thylakoid membrane structure and function regulation, as well as in the construction of artificial photosynthetic systems and the development of plant photoprotection strategies .

Cat. No.	Product Name	Type

HY-134174A

*1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium* 16:0-18:1 PA	Biochemical Assay Reagents
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium (16:0-18:1 PA) is a phospholipid with activities in regulating biological membrane fluidity and participating in cell signal transduction. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium can be used to study the effects on the activity of chloroplast envelope monogalactosyldiacylglycerol (MGDG) synthase. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium plays an important role in cell membrane integrity and function.

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium

16:0-18:1 PA

Biochemical Assay Reagents

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium (16:0-18:1 PA) is a phospholipid with activities in regulating biological membrane fluidity and participating in cell signal transduction. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium can be used to study the effects on the activity of chloroplast envelope monogalactosyldiacylglycerol (MGDG) synthase. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium plays an important role in cell membrane integrity and function.

Cat. No.	Product Name	Target	Research Area

HY-137798

Chromozym PL	Fluorescent Dye	Others
Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N12540

*Monogalactosyldiacylglycerol* MGDG	Structural Classification other families Oplismenus burmannii Plants Lipid Source Classification	DNA/RNA Synthesis Apoptosis
Monogalactosyldiacylglycerol (MGDG) is a galactolipid with anti-inflammatory and anticancer activities, which is found in photosynthetic organisms. Monogalactosyldiacylglycerol is a potent DNA polymerase inhibitor with pro-apoptotic activity. Monogalactosyldiacylglycerol inhibits the synthesis of LPS (HY-D1056)-induced inflammation-related proteins (Ex-FABP, Avidin, Serum Amyloid A). Monogalactosyldiacylglycerol exerts an anti-proliferative effect on chicken articular chondrocytes . Monogalactosyldiacylglycerol can be used in research related to osteoarthritis, cancer and inflammatory diseases .

HY-N9677

Digalactosyldiacylglycerol	Structural Classification Natural Products Amaranthaceae Plants Spinacia oleracea L. Source Classification	Herbicide
Digalactosyldiacylglycerol is a membrane structure stabilizer that selectively acts on photosystem II light-harvesting complex II (LHCII), serving as a natural bilayer-forming lipid in plant thylakoid membranes. Digalactosyldiacylglycerol constructs a lipid bilayer environment with monogalactosyldiacylglycerol (MGDG) in a 2:1 molar ratio, stabilizing the supramolecular structure of LHCII through interactions such as hydrogen bonding. Its core activity is maintaining thylakoid membrane stacking (grana formation) and supporting photosynthesis-related functions, while also possessing functions in light harvesting assistance and excitation energy quenching regulation under light stress. Digalactosyldiacylglycerol can be used in research on plant photosynthesis mechanisms, thylakoid membrane structure and function regulation, as well as in the construction of artificial photosynthetic systems and the development of plant photoprotection strategies .

Cat. No.	Product Name		Classification

HY-134174A

*1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium* 16:0-18:1 PA		Phospholipids
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium (16:0-18:1 PA) is a phospholipid with activities in regulating biological membrane fluidity and participating in cell signal transduction. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium can be used to study the effects on the activity of chloroplast envelope monogalactosyldiacylglycerol (MGDG) synthase. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium plays an important role in cell membrane integrity and function.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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monogalactosyldiacylglycerol

Inhibitors & Agonists

Biochemical Assay Reagents

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