2 Results for "

mouse paw oedema

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "mouse paw oedema" in MCE Product Catalog:

24
Beta-Sitosterol (purity>98%)
Beta-Sitosterol (purity>98%)
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24 Cited Publications
Cat. No.: HY-N0171A
CAS No.: 83-46-5
Synonyms: β-Sitosterol (purity>98%); 22,23-Dihydrostigmasterol (purity>98%)
Category:  

Cardiovascular Disease Leguminosae Glycine max (L.) merr Plants Disease Research Fields Inflammation/Immunology Steroids

Target:  

Bacterial Apoptosis Reactive Oxygen Species (ROS) MDM-2/p53 Caspase PARP MMP Bcl-2 Family HIF/HIF Prolyl-Hydroxylase TNF Receptor Interleukin Related NF-κB mTOR Lactate Dehydrogenase CDK Glutathione Peroxidase SOD

Beta-Sitosterol (purity>98%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc .
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Gnaphaliin
Gnaphaliin
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Cat. No.: HY-W747035
CAS No.: 33803-42-8
Category:  

Flavonols Flavonoids Asteraceae Helichrysum italicum (Roth) G.Don Plants

Target:  

Biochemical Assay Reagents

Gnaphaliin is a flavonoid compound that exerts antioxidant, anti-inflammatory, and tracheal smooth muscle relaxant effects by inhibiting lipid peroxidation, scavenging free radicals, chelating trace elements, and reducing neutrophil infiltration. Gnaphaliin can be used in research on asthma, inflammation, and atherosclerosis .
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