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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
myosin B
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "myosin B" in MCE Product Catalog:
24
24 Cited Publications
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
ML-7 hydrochloride is a selective and highly specific myosin light chain kinase (MLCK) inhibitor that acts as a trabecular meshwork (TM) relaxant. ML-7 hydrochloride enhances Quinocetone (HY-123581)-induced phosphorylation of ERK, p38 MAPK and JNK, attenuates Akt activation, and promotes apoptosis of hepatocellular carcinoma cells. ML-7 hydrochloride reduces Th2 cytokine secretion by inhibiting MLCK, while alleviating smooth muscle hyperplasia and collagen deposition . As a non-antibiotic adjuvant, ML-7 hydrochloride restores the sensitivity of drug-resistant bacteria to Tigecycline (HY-B0117) . ML-7 hydrochloride can be used in research related to glaucoma, hepatocellular carcinoma, asthma, and Klebsiella pneumoniae infection .
Cat. No.: HY-161608
CAS No.: 3034189-56-2
Target:
Research Areas:
Myosin modulator 1 (Compound B141) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 0.42, 0.13 and 3.09 μM, respectively. Myosin modulator 1 regulates systolic cardiac performance in Sprague Dawley rats .
Cat. No.: HY-161609
CAS No.: 3034189-87-9
Target:
Research Areas:
Myosin modulator 2 (Compound B172) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 2.013, 2.94 and 20.93 μM, respectively. Myosin modulator 2 regulates systolic cardiac performance in Sprague Dawley rats .
Cat. No.: HY-119038
CAS No.: 109376-83-2
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
ML-7 is a selective and highly specific myosin light chain kinase (MLCK) inhibitor that acts as a trabecular meshwork (TM) relaxant. ML-7 enhances Quinocetone (HY-123581)-induced phosphorylation of ERK, p38 MAPK and JNK, attenuates Akt activation, and promotes apoptosis of hepatocellular carcinoma cells. ML-7 reduces Th2 cytokine secretion by inhibiting MLCK, while alleviating smooth muscle hyperplasia and collagen deposition . As a non-antibiotic adjuvant, ML-7 restores the sensitivity of drug-resistant bacteria to Tigecycline (HY-B0117) . ML-7 can be used in research related to glaucoma, hepatocellular carcinoma, asthma, and Klebsiella pneumoniae infection .
Cat. No.: HY-N15301
Category:
Cat. No.: HY-134248
CAS No.: 10058-66-9
Synonyms: 7-Deazaadenosine 5'-triphosphate
Target:
Research Areas:
Tubercidin 5'-triphosphate (7-Deazaadenosine 5'-triphosphate) (Compound II) is an ATP (HY-B2176) analogue. Tubercidin 5'-triphosphate is hydrolyzable by Myosin B. Tubercidin 5'-triphosphate induces weak contraction of rabbit psoas myofibrils .
Cat. No.: HY-134248A
Synonyms: 7-Deazaadenosine 5'-triphosphate tetrasodium
Target:
Research Areas:
Tubercidin 5'-triphosphate tetrasodium (7-Deazaadenosine 5'-triphosphate tetrasodium) is an ATP (HY-B2176) analogue. Tubercidin 5'-triphosphate tetrasodium is hydrolyzable by Myosin B. Tubercidin 5'-triphosphate tetrasodium induces weak contraction of rabbit psoas myofibrils .
Cat. No.: HY-P704107
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MYL12B; SHUJUN-1; myosin Light Chain 12B; MLC-2A; MRLC2; MLC20; myosin Regulatory Light Chain 20 KDa; MLC-2; myosin, Light Chain 12B, Regulatory; myosin Regulatory Light Chain 2-B, Smooth Muscle Isoform; myosin Regulatory Light Chain MRLC2; MYLC2B; myosin
Species:
Human
Source:
E. coli
Cat. No.: HY-P705598
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MYO3B; Non-Specific Serine/Threonine Protein Kinase; myosin IIIB; Uncharacterized Protein MYO3B; myosin-IIIb
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704105
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MYL12A; myosin Regulatory Light Chain MRLC3; myosin Light Chain 12A; Epididymis Secretory Protein Li 24; MRLC3; myosin Regulatory Light Chain 12A; MRCL3; myosin Regulatory Light Chain 3; MLCB; myosin RLC; MYL2B; HEL-S-24; myosin, Light Polypeptide, Regula
Species:
Human
Source:
E. coli
Cat. No.: HY-P86696A
Synonyms: Deafness autosomal dominant 11; Deafness autosomal recessive 2; DFNA11; DFNB 2; DFNB2; Myo7a; myosin 7a; myosin VIIa; MYU7A; NSRD 2; NSRD2; Ush 1B; Ush1b; Usher syndrome 1B.
Cat. No.: HY-N15301A
Target:
Research Areas:
Cat. No.: HY-P703359
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPP1CB; myosin Phosphatase; Protein Phosphatase 1 Catalytic Subunit Beta; PP1Cdelta; PP-1B; PP1Cbeta; PPP1beta; Protein Phosphatase 1, Catalytic Subunit, Beta Isoform; PP1beta; Epididymis Secretory Sperm Binding Protein Li 80p; PPP1CD; Protein-Serine/Thre
Species:
Human
Source:
E. coli
Cat. No.: HY-P704199
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PPP1CB; myosin Phosphatase; Protein Phosphatase 1 Catalytic Subunit Beta; PP1Cdelta; PP-1B; PP1Cbeta; PPP1beta; Protein Phosphatase 1, Catalytic Subunit, Beta Isoform; PP1beta; Epididymis Secretory Sperm Binding Protein Li 80p; PPP1CD; Protein-Serine/Thre
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
