MYO18B Antibody (YA10069)
(Synonyms: Unconventional myosin-XVIIIb, MYO18B)MYO18B Antibody (YA10069) is a Mouse-derived and non-conjugated IgG2b Monoclonal antibody, targeting to MYO18B.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IHC-P, FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:1000-5000 | 1:100-200 | 1:10-50 |
Product Details
MYO18B Antibody (YA10069) is a Mouse-derived and non-conjugated IgG2b Monoclonal antibody, targeting to MYO18B.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 36 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 285 kDa
Purified recombinant protein of human MYO18B.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MYO18B may be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth
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Subcellular Localization
Cytoplasm; Nucleus; Cytoplasm, myofibril, sarcomere
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Expression
Tissue_Specificity: Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus. -
Isoforms & Post-Translational Modification
MYO18B has 3 isoforms, Q8IUG5-1: amino acid length is 2567, molecular weight is 285215 Da (predicted); Q8IUG5-2: amino acid length is 2080, molecular weight is 233701 Da (predicted); Q8IUG5-3: amino acid length is 2568, molecular weight is 285343 Da (predicted).
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Subunit
Homodimer.
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SwissProt ID
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Synonyms
Unconventional myosin-XVIIIb, MYO18B
Documentation
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