MYH10 Antibody (YA3114)(PBS only)

Cat. No.: HY-P83369A: Data Sheet User Guide for Antibodies
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MYH10 Antibody (YA3114) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MYH10.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명
References

제품 설명

MYH10 Antibody (YA3114) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MYH10.

Host

Rabbit

분자량

Predicted band size: 229 kDa;

Observed band size: 229 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

P35580

Gene ID

4628 [NCBI]

Immunogen

A synthetic peptide of human non-muscle Myosin IIB/MYH10 aa846-1066.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9; (Microbial infection) Acts as a receptor for herpes simplex virus 1/HHV-1 envelope glycoprotein B

Subcellular Localization：Cell projection, lamellipodium; Cell membrane

Expression：
Tissue_specificity:Isoform 1 is expressed in cerebellum and spinal chord. Isoform 2 is expressed in cerebrum and retina. Isoform 3 is expressed in the cerebrum and to a much lower extent in cerebellum

Isoforms & Post-Translational Modification：P35580 has 5 isomers: P35580-1: 228999 Da (predicted); P35580-2: 230779 Da (predicted); P35580-3: 231369 Da (predicted); P35580-4: 232528 Da (predicted); P35580-5: 230030 Da (predicted).
Phosphorylated by ABL2

Subunit：Myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Interacts with PLEKHG6 (PubMed:16721066). Interacts with ECPAS (PubMed:20682791). Interacts with KIF26B (By similarity). Interacts with LARP6 (PubMed:20603131). Interacts with MCC (PubMed:22480440). Interacts with CFAP95 (PubMed:28345668)

Research Field

Signal Transduction

Synonyms

NMMHCB; NMMHC-IIB; Myosin-10, Myosin heavy chain 10, Non-muscle myosin heavy chain B, Non-muscle myosin heavy chain IIb, NMMHC-B, NMMHC II-b, NMMHC-IIB, MYH10

각종 서류

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/u2os-cell.html [Content Brief]