2 Results for "

nucleoside analogue therapy

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "nucleoside analogue therapy" in MCE Product Catalog:

Xalnesiran sodium
Xalnesiran sodium
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Cat. No.: HY-145638A
CAS No.: 2538784-49-3
Purity:  95.90%
Synonyms: RO7445482 sodium
Target:  

HBV

Research Areas:  

Infection

Xalnesiran (RO7445482) sodium is a small interfering RNA molecule that targets a conserved region of the
hepatitis B virus (HBV) genome . Xalnesiran sodium can be used for the research of chronic hepatitis B infection .
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LCB-2151
LCB-2151
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Cat. No.: HY-175673
CAS No.: 2211175-99-2
Target:  

Carnitine Palmitoyltransferase (CPT) Apoptosis Oxidative Phosphorylation Mitochondrial Metabolism Reactive Oxygen Species (ROS)

Research Areas:  

Cancer

LCB-2151 (Compound 2), a nucleoside analogue, is an anticancer agent. LCB-2151 disrupts the two primary sources of ATP production (glycolysis and mitochondrial oxidative phosphorylation), reducing the bioenergetic capacity of KRAS-mutated pancreatic cancer cells and inducing ROS formation. LCB-2151 effectively inhibits key enzymes (such as CACT and CPT2) in glycolysis, the TCA cycle and fatty acid β-oxidation. LCB-2151 has significant cytotoxicity and induces cells apoptosis. LCB-2151 can be used for radiation therapy of cancers research .
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