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pregnancy

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Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-N0437
    Progesterone
    Maximum Cited Publications
    34 Publications Verification

    Pregn-4-ene-3,20-dione

    Progesterone Receptor Endogenous Metabolite Cardiovascular Disease Infection Neurological Disease Cancer
    Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone
  • HY-W015883
    Fumaric acid
    4 Publications Verification

    Environmental Pollutants Endogenous Metabolite NF-κB p38 MAPK Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
    Fumaric acid
  • HY-N1445
    Isoquercitrin
    5+ Cited Publications

    Isoquercetin; Quercetin 3-glucoside

    NF-κB NO Synthase Inflammation/Immunology Cancer
    Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .
    Isoquercitrin
  • HY-B1108
    Labetalol hydrochloride
    5 Publications Verification

    AH-5158 hydrochloride; Sch-15719W

    Adrenergic Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology
    Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .
    Labetalol hydrochloride
  • HY-121383
    Labetalol
    5 Publications Verification

    AH5158; Sch-15719W free base

    Adrenergic Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology
    Labetalol (AH5158) is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .
    Labetalol
  • HY-B2068
    Iron sucrose
    1 Publications Verification

    Iron saccharate

    Reactive Oxygen Species (ROS) Metabolic Disease Cancer
    Iron sucrose (Iron saccharate) is a intravenous iron preparation and a pro-oxidant agent. Iron sucrose has the potential for iron deficiency anemia treatment .
    Iron sucrose
  • HY-W040047

    Endogenous Metabolite Metabolic Disease
    Pregnanediol 3-glucuronide is the main terminal metabolite of Progesterone (HY-N0437). Pregnanediol 3-glucuronide is the metabolite of Progesterone produced in the liver through hydroxylation and glucuronidation, with high hydrophilicity and easy excretion through urine. A decrease in the level of Pregnanediol 3-glucuronide is associated with an increased risk of thyroid cancer, while an increase is associated with the state of pregnancy. Pregnanediol 3-glucuronide is of great significance in the monitoring of female reproductive health, pregnancy assessment, and the diagnosis of endocrine diseases .
    Pregnanediol 3-glucuronide
  • HY-N0437R
    Progesterone (Standard)
    Maximum Cited Publications
    34 Publications Verification

    Pregn-4-ene-3,20-dione (Standard)

    Reference Standards Progesterone Receptor Endogenous Metabolite Cardiovascular Disease Cancer
    Progesterone (Standard) is the analytical standard of Progesterone. This product is intended for research and analytical applications. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone (Standard)
  • HY-15731

    Estrogen Receptor/ERR Endogenous Metabolite NO Synthase Cardiovascular Disease Cancer
    Estetrol, an orally active estrogen synthesized exclusively during pregnancy by the human fetal liver, is a selective nuclear estrogen receptor modulator. Estetrol binds ERα as well as ERβ (with a fourfold lower affinity). Estetrol increases eNOS expression/activity and NO synthesis in endothelial cells. Estetrol exerts estrogenic actions on the endometrium or the central nervous system but presents antagonistic effects on the breast. Estetrol can be used in contraception and menopausal hormone research .
    Estetrol
  • HY-113315

    Endogenous Metabolite Metabolic Disease
    3β-Hydroxy-5-cholenoic acid is a steroidal monohydroxy bile acid and serves as a substrate for sulfation reactions. It is applicable to the research of extrahepatic biliary atresia and recurrent intrahepatic cholestasis of pregnancy .
    3b-Hydroxy-5-cholenoic acid
  • HY-N0437S

    Pregn-4-ene-3,20-dione-d9

    Progesterone Receptor Endogenous Metabolite Cardiovascular Disease Cancer
    Progesterone-d9 is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone-d9
  • HY-W015883A
    Fumaric acid disodium
    4 Publications Verification

    Endogenous Metabolite NF-κB p38 MAPK Cardiovascular Disease Inflammation/Immunology
    Fumaric acid disodium is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid disodium exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid disodium can be used in the study of pregnancy-induced hypertension .
    Fumaric acid disodium
  • HY-B1794
    Thiethylperazine
    3 Publications Verification

    Dopamine Receptor Histamine Receptor Bacterial Amyloid-β Infection Neurological Disease
    Thiethylperazine, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine has anti-emetic, antipsychotic and antimicrobial effects .
    Thiethylperazine
  • HY-19307

    Integrin Interleukin Related Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    SB-273005 is an orally active non-peptide αvβ3 integrin antagonist with Ki values of 1.2 nM and 0.3 nM for αvβ3 and αvβ5, respectively. SB-273005 blocks the binding of integrins to the RGD sequence in the extracellular matrix. SB-273005 inhibits Rictor phosphorylation and reduces IL-10 secretion. SB-273005 inhibits inflammation, prevents bone loss, regulates vascular smooth muscle function, and reverses pregnancy-induced immune deviation. SB-273005 can be used in the study of rheumatoid arthritis, osteoporosis, and aneurysms. .
    SB-273005
  • HY-111614

    Progesterone Receptor Metabolic Disease Cancer
    Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity . Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research .
    Melengestrol acetate
  • HY-17587
    4-Methylbenzylidene camphor
    2 Publications Verification

    4-MBC; Enzacamene

    Apoptosis PI3K Akt ERK Metabolic Disease
    4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .
    4-Methylbenzylidene camphor
  • HY-A0130

    Sulfametopyrazine; AS-18908

    Parasite Bacterial Infection Inflammation/Immunology
    Sulfalene (Sulfametopyrazine) is an orally active antimalarial agent. Sulfalene competes with para-aminobenzoic acid in plasmodial and bacterial folic acid synthesis pathways. Sulfalene reduces trachoma-associated pathological changes. Sulfalene can be used for the research of acute falciparum malaria, Schistosoma mansoni infection, trachoma, chronic bronchitis, and bacteriuria in pregnancy .
    Sulfalene
  • HY-B0487

    Pregneninolone; 17α-Ethynyltestosterone

    Estrogen Receptor/ERR Metabolic Disease
    Ethisterone (Pregneninolone; 17α-Ethynyltestosterone) is a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone has almost no effect on the phagocytic activity of the reticuloendothelial system in male guinea pigs, while in utero exposure can induce abnormalities in the urogenital system of offspring .
    Ethisterone
  • HY-19360

    SHB 286; CP-34089; ZK-57671

    Prostaglandin Receptor Cardiovascular Disease Inflammation/Immunology
    Sulprostone (SHB 286) is a potent and selective EP3 receptor agonist. Sulprostone (SHB 286) is a prostaglandin E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for the research of pregnancy termination and hemorrhages during delivery .
    Sulprostone
  • HY-128428

    15(S)-15-Methyl Prostaglandin F2α; 15-Methyl-PGF2α

    Prostaglandin Receptor Endocrinology
    Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a metabolically stable synthetic analog of prostaglandin F2α. Carboprost stimulates uterine contractions and induces abortion. Carboprost is used for postpartum hemorrhage due to uterine atony and for the termination of pregnancy in the second trimester .
    Carboprost
  • HY-W007346

    3-Methoxybenzaldehyde

    Endogenous Metabolite Inflammation/Immunology
    m-Anisaldehyde (3-Methoxybenzaldehyde) is an endogenous metabolite. 3-Methoxybenzaldehyde is associated with thyroid autoimmunity during early pregnancy .
    m-Anisaldehyde
  • HY-111614S2

    Isotope-Labeled Compounds Progesterone Receptor Metabolic Disease Cancer
    Melengestrol acetate-d3 is the deuterium labeled Melengestrol acetate. Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity . Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research .
    Melengestrol acetate-d3
  • HY-W008764

    9,10-Anthracenedione, 1,5-dihydroxy-

    Drug Derivative Others
    Anthrarufin (9,10-Anthracenedione, 1,5-dihydroxy-_) is an anthraquinone compound that has an inhibitory effect on the activity of the uterine mucosa during pregnancy .
    Anthrarufin
  • HY-30215

    Endogenous Metabolite Metabolic Disease Endocrinology
    (S)-Leucic acid is a metabolite of Leucine. (S)-Leucic acid has anabolic effects, particularly promoting muscle protein synthesis. (S)-Leucic acid can be used in the diagnosis of pregnancy loss .
    (S)-Leucic acid
  • HY-141616

    Endogenous Metabolite Inflammation/Immunology
    1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine is an endogenous metabolite present in Blood that can be used for the research of Pregnancy and Sepsis .
    1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine
  • HY-B2112

    mAChR Neurological Disease
    Valethamate bromide is an ester, serving as an effective rapidly acting anticholinergic antispasmodic and muscle relaxant. Valethamate bromide accelerates labor by improving cervical dilation. Valethamate bromide can significantly shorten the labor process and have fewer side effects .
    Valethamate bromide
  • HY-W015883S1

    Isotope-Labeled Compounds Endogenous Metabolite NF-κB p38 MAPK Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Fumaric acid- 13C2 is the 13C-labeled Fumaric acid (HY-W015883). Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
    Fumaric acid-13C2
  • HY-N1445R
    Isoquercitrin (Standard)
    1 Publications Verification

    Isoquercetin (Standard); Quercetin 3-glucoside (Standard)

    Reference Standards NF-κB NO Synthase Inflammation/Immunology Cancer
    Isoquercetin (Standard) is the analytical standard of Isoquercetin. This product is intended for research and analytical applications. Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .
    Isoquercitrin (Standard)
  • HY-W015883R

    Reference Standards Endogenous Metabolite NF-κB p38 MAPK Metabolic Disease Inflammation/Immunology
    Fumaric acid (Standard) is the analytical standard of Fumaric acid. This product is intended for research and analytical applications. Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
    Fumaric acid (Standard)
  • HY-B1108R
    Labetalol hydrochloride (Standard)
    4 Publications Verification

    AH-5158 hydrochloride(Standard); Sch-15719W (Standard)

    Reference Standards Adrenergic Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology
    Labetalol hydrochloride (Standard) is the analytical standard of Labetalol hydrochloride (HY-B1108). This product is intended for research and analytical applications. Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .
    Labetalol hydrochloride (Standard)
  • HY-N0437S2
    Progesterone-13C3
    1 Publications Verification

    Pregn-4-ene-3,20-dione-13C3

    Isotope-Labeled Compounds Progesterone Receptor Endogenous Metabolite Cardiovascular Disease Cancer
    Progesterone- 13C3 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone-13C3
  • HY-105128

    WIN 32729

    3β-HSD Endocrinology
    Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC50 of 1.45 nM. Epostane blocks ovulation and pregnancy in rats .
    Epostane
  • HY-135730

    Endogenous Metabolite Endocrinology
    Aglepristone is a synthetic steroidal antiprogestin with abortifacient activity. Aglepristone is used exclusively as an abortifacient in pregnant animals. Aglepristone has been shown to be a safe and effective abortifacient in the second trimester of pregnancy. Aglepristone causes termination of pregnancy and does not cause fetal resorption. During aglepristone treatment, an increase in plasma concentrations of prolactin was observed, while progesterone levels remained unchanged. The use of aglepristone also resulted in early arrest of corpus luteum function and a shortening of the estrus interval .
    Aglepristone
  • HY-113208

    13,14-Dihydro-15-keto-PGF2α

    Endogenous Metabolite Others
    13,14-Dihydro-15-keto Prostaglandin F2α (13,14-Dihydro-15-keto-PGF2α) is an endogenous metabolite present in Blood that can be used for the research of Pregnancy .
    13,14-Dihydro-15-keto Prostaglandin F2α
  • HY-121383R

    AH5158 (Standard); Sch-15719W free base (Standard)

    Reference Standards Adrenergic Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology
    Labetalol (Standard) is the analytical standard of Labetalol. This product is intended for research and analytical applications. Labetalol (AH5158) is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .
    Labetalol (Standard)
  • HY-30215R

    Reference Standards Endogenous Metabolite Metabolic Disease Endocrinology
    (S)-Leucic acid (Standard) is the analytical standard of (S)-Leucic acid (HY-30215). This product is intended for research and analytical applications. (S)-Leucic acid is a metabolite of Leucine. (S)-Leucic acid has anabolic effects, particularly promoting muscle protein synthesis. (S)-Leucic acid can be used in the diagnosis of pregnancy loss .
    (S)-Leucic acid (Standard)
  • HY-119485

    (+)-Labetalol

    Adrenergic Receptor Others
    Dilevalol ((+)-Labetalol) is a novel agonist of ß2-receptor that can be used to suppress hypertension during pregnancy .
    Dilevalol
  • HY-N0437S3

    Pregn-4-ene-3,20-dione-13C2

    Isotope-Labeled Compounds Progesterone Receptor Endogenous Metabolite Cardiovascular Disease Cancer
    Progesterone- 13C2 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone-13C2
  • HY-113105

    Estriol 16-glucosiduronate

    Endogenous Metabolite Others
    Estriol 16α-(β-D-glucuronide) is an endogenous metabolite present in Urine that can be used for the research of Pregnancy .
    Estriol 16α-(β-D-glucuronide)
  • HY-16741

    OBE001

    Oxytocin Receptor Endocrinology
    Erlosiban (OBE001) is an orally active non-peptide type oxytocin receptor antagonist. Erlosiban inhibits the increase of intracellular calcium concentration, thereby reducing uterine smooth muscle contraction. Erlosiban can be used for research on premature birth and to improve embryo implantation and pregnancy rate in assisted reproductive technology (AR).
    Erlosiban
  • HY-B1794A
    Thiethylperazine dimaleate
    3 Publications Verification

    Dopamine Receptor Histamine Receptor Bacterial Amyloid-β Infection Neurological Disease
    Thiethylperazine dimaleate, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine dimaleate is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine dimaleate has anti-emetic, antipsychotic and antimicrobial effects .
    Thiethylperazine dimaleate
  • HY-P11340

    MHC Infection Inflammation/Immunology
    VMAPRTLFL is a 9-mer peptide derived from the signal peptide of HLA-G and can serve as a peptide ligand for HLA-E. VMAPRTLFL plays a crucial role in regulating the functions of adaptive natural killer (NK) cells. Specifically, VMAPRTLFL enriches FcεRγ - adaptive NK cells, upregulates the expression of CD25, and enhances their proliferative activity, antibody-dependent cellular cytotoxicity (ADCC), and IFN-γ release. VMAPRTLFL can be used in research related to human cytomegalovirus (HCMV) infection, transplant rejection, and pregnancy immunity .
    VMAPRTLFL
  • HY-W040047S

    Endogenous Metabolite Isotope-Labeled Compounds Endocrinology
    Pregnanediol 3-glucuronide is the main end-metabolite of Progesterone (HY-N0437). Pregnanediol 3-glucuronide is a metabolite of Progesterone formed by hydroxylation and glucuronidation in the liver, with high hydrophilicity and easy excretion through urine. Pregnanediol 3-glucuronide excretion rate of ≥ 9 μmol/24 h can serve as biochemical evidence of ovulation. Pregnanediol 3-glucuronide reflects the quality of the luteal phase, and a level of < 7 μmol/24 h may indicate anovulation or luteal insufficiency. Pregnanediol 3-glucuronide holds significant importance in monitoring female reproductive health, assessing pregnancy, and diagnosing endocrine disorders.
    Pregnanediol 3-glucuronide-13C5
  • HY-113169

    Estriol 3-β-D-glucuronide

    Endogenous Metabolite Metabolic Disease
    Estriol-3-glucuronide exists in amniotic fluid during normal pregnancy and occurs naturally in urine .
    Estriol 3-glucuronide
  • HY-106887

    Neprilysin Neurological Disease
    SCH 32615 is an enkephalinase (the enzymes responsible for the degradation of endogenous enkephalins) inhibitor. SCH 32615 can enhance surgery- and pregnancy-induced analgesia in mice .
    SCH 32615
  • HY-128428R

    15(S)-15-Methyl Prostaglandin F2α (Standard); 15-Methyl-PGF2α (Standard)

    Reference Standards Prostaglandin Receptor Endocrinology
    Carboprost (Standard) is the analytical standard of Carboprost. This product is intended for research and analytical applications. Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a metabolically stable synthetic analog of prostaglandin F2α. Carboprost stimulates uterine contractions and induces abortion. Carboprost is used for postpartum hemorrhage due to uterine atony and for the termination of pregnancy in the second trimester .
    Carboprost (Standard)
  • HY-17587R

    4-MBC (Standard); Enzacamene (Standard)

    Reference Standards Apoptosis PI3K Akt ERK Metabolic Disease
    4-Methylbenzylidene camphor (Standard) is the analytical standard of 4-Methylbenzylidene camphor. This product is intended for research and analytical applications. 4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .
    4-Methylbenzylidene camphor (Standard)
  • HY-119482

    Progesterone Receptor Others
    Cymipristone (ZXH-951), a progesterone receptor antagonist, is used potentially for termination of intrauterine pregnancy .
    Cymipristone
  • HY-122299

    Ro 11-1430

    Drug Derivative Others
    Motretinide (Ro 11-1430) is an aromatic retinoic acid with teratogenic activity. Motretinide can be used in studies on medication guidance during pregnancy .
    Motretinide
  • HY-N0437S1

    Pregn-4-ene-3,20-dione-13C5

    Isotope-Labeled Compounds Progesterone Receptor Endogenous Metabolite Cardiovascular Disease Cancer
    Progesterone- 13C5 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone-13C5

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