434-03-7
Chemical Structure
Ethisterone
Synonym(s): Pregneninolone; 17α-Ethynyltestosterone
- CAS No.: 434-03-7
- Formula:C21H28O2
- Molecular Weight:312.45
IUPAC Name: (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: CHNXZKVNWQUJIB-CEGNMAFCSA-N
SMILES: C[C@@]1([C@]2(O)C#C)[C@](CC2)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])CC1
Biological Activity: Ethisterone (Pregneninolone; 17α-Ethynyltestosterone) is a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone has almost no effect on the phagocytic activity of the reticuloendothelial system in male guinea pigs, while in utero exposure can induce abnormalities in the urogenital system of offspring[1][2].
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Ethisterone | 98.02% | Ethisterone (Pregneninolone; 17α-Ethynyltestosterone) is a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone has almost no effect on the phagocytic activity of the reticuloendothelial system in male guinea pigs, while in utero exposure can induce abnormalities in the urogenital system of offspring. | ||||||||||||||||||||
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Ethisterone (Standard) | ≥98% | Ethisterone (Pregneninolone; 17α-Ethynyltestosterone) (Standard) is the analytical standard of Ethisterone (HY-B0487). This product is intended for research and analytical applications. Ethisterone is a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone has almost no effect on the phagocytic activity of the reticuloendothelial system in male guinea pigs, while in utero exposure can induce abnormalities in the urogenital system of offspring. | ||||||||||||||||||||
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Ethisterone-13C2 | Ethisterone-13C2 (Pregneninolone-13C2) is the 13C-labeled Ethisterone (HY-B0487). Ethisterone (Pregneninolone; 17α-Ethynyltestosterone) is a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone has almost no effect on the phagocytic activity of the reticuloendothelial system in male guinea pigs, while in utero exposure can induce abnormalities in the urogenital system of offspring. | |||||||||||||||||||||
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- [1]. Nicol T, et al. Effect of Ethisterone, β-Œstradiol and Progesterone on the Phagocytic Activity of the Reticulo-Endothelial System[J]. Nature, 1957, 179(4553): 261-261.
- [2]. Beral V, et al. Randomised trial of high doses of stilboestrol and ethisterone therapy in pregnancy: long-term follow-up of the children. J Epidemiol Community Health. 1981;35(3):155-160. [Content Brief]
