Ethisterone
Based on 1 publication(s) in Google Scholar
Ethisterone (Pregneninolone; 17α-Ethynyltestosterone) is a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone has almost no effect on the phagocytic activity of the reticuloendothelial system in male guinea pigs, while in utero exposure can induce abnormalities in the urogenital system of offspring.
For research use only. We do not sell to patients.
- Purity: 98.02%
- CAS No.: 434-03-7
- Formula: C21H28O2
- Molecular Weight:312.45
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Ethisterone
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Biological Activity
Ethisterone acts as an inducer of urogenital abnormalities, with in utero exposure linked to increased offspring urogenital abnormality prevalence, higher risk with earlier exposure onset[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Guinea pigs (Male)[1]
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Dosage:0.5 mg
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Administration:i.m.; daily; 2 weeks; 4 weeks
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Result:Contained a moderate number of dye granules in macrophages of the spleen, liver, and lymph nodes.
Showed vital staining appearances closely resembling those of control animals.
Chemical Information
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CAS No. 434-03-7
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Appearance Solid
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Molecular Weight 312.45
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Formula C21H28O2
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Color Light yellow to yellow
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SMILES
C[C@@]1([C@]2(O)C#C)[C@](CC2)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])CC1
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Synonyms
Pregneninolone; 17α-Ethynyltestosterone
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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Commun Biol
5α-Reductase underscores the development of pectoral fin breeding tubercles in zebrafish. [Abstract]2026 Apr 24;9(1):873. PMID: 42032132
Solvent & Solubility
Ethanol : 1 mg/mL (3.20 mM; ultrasonic and warming and heat to 60°C)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 3.2005 mL | 16.0026 mL | 32.0051 mL | 80.0128 mL |
Ethisterone Related Classifications
HY-B0487 Related Classifications
Powered by Bioz
- Ethisterone
- 434-03-7
- Pregneninolone
- 17α-Ethynyltestosterone
- Estrogen Receptor/ERR
- male guinea pigs
- diabetic pregnancies
- infertility
- amenorrhoea
- progestogen sex hormone
- female reproductive function
- reticulo-endothelial system
- male sexual/social function
- spontaneous abortion
- urogenital abnormalities
- Inhibitor
- inhibitor
- inhibit