93 Results for "

proteoglycan

" in MedChemExpress (MCE) Product Catalog:
Products (93)

93 Results for "proteoglycan" in MCE Product Catalog:

23
23 Publications Verification
Cat. No.: HY-101916
CAS No.: 9050-30-0
Heparan sulfate, a complex and linear polysaccharide, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix.
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19
19 Cited Publications
Cat. No.: HY-E70005A
CAS No.: 9001-12-1
Synonyms: EC 3.4.24.3
Target:  

MMP

Research Areas:  

Others

Collagenase, Type I is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type I breaks down collagens 1, 3, 7, 8, 10, gelatin, proteoglycans, aggrecan .

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9
9 Cited Publications
Cat. No.: HY-P3160
CAS No.: 86088-83-7
Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans .
This product is a human Fibronectin obtained by recombinant expression in a rice expression system.
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3
3 Cited Publications
Cat. No.: HY-110135
CAS No.: 374620-70-9
Purity:  98.88%
Target:  

IGF-1R

NBI-31772 is a non-selective IGFBP inhibitor (Ki=47 nM). NBI-31772 has neuroprotective effects and reduces infarct volume during cerebral ischemia. NBI-31772 can also restore or enhance proteoglycan synthesis in osteoarticular chondrocytes. In addition, NBI-31772 also increases the effect of IGF3 on zebrafish oocyte maturation .
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3
3 Cited Publications
Cat. No.: HY-P79236
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: agrin proteoglycan; Agrin; AGRN
Species:  
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-N11287A
CAS No.: 108320-89-4
UDP-xylose disodium is an endogenous sugar nucleotide and a catalytic substrate of UDP-xylose disodium synthase (UXS). UDP-xylose disodium is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites and oligosaccharides in plants, vertebrates and fungi, and participates in the synthesis of proteoglycans as a glycosyl donor. UDP-xylose disodium participates in the regulation of the synthesis of extracellular matrix components and can be used to study the mechanism of proteoglycan biosynthesis in glycobiology and related diseases (such as connective tissue diseases)[1][2].
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2
2 Cited Publications
Cat. No.: HY-P2727
CAS No.: 9024-13-9
Synonyms: ChABC
Research Areas:  

Neurological Disease

Chondroitinase ABC (ChABC) is an enzyme that degrades glycosaminoglycan side-chains of chondroitin sulfate (CS-GAG) from the chondroitin sulfate proteoglycan (CSPG) core protein. Chondroitinase ABC facilitates reinnervation by degrading CS-GAGs around motoneurons. Chondroitinase ABC has the potential for the research of spinal injury .
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2
2 Cited Publications
Cat. No.: HY-P86463
Synonyms: LHR antibody; BA-1 antibody; CD 44 antibody; CD44 antibody; CD44 antigen antibody; CD44 molecule; Indian blood group; antibody; CD44 molecule antibody; CD44_HUMAN antibody; CDw44 antibody; CDW44 antigen antibody; Cell surface glycoprotein CD44 antibody; chondroitin sulfate proteoglycan 8 antibody; CSPG8 antibody; ECMR-III antibody; Epican antibody; Extracellular matrix receptor III antibody; GP90 lymphocyte homing/adhesion receptor antibody

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P0063
CAS No.: 89030-95-5
Synonyms: GHK-Cu
Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration .
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1
1 Cited Publications
Cat. No.: HY-N6612
CAS No.: 6556-12-3
D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers, and its derivatives also possess anti-tumor activity .
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1
1 Cited Publications
Cat. No.: HY-124704
CAS No.: 2158198-77-5
Purity:  98.09%
Target:  

SULT

Research Areas:  

Neurological Disease

Chst15-IN-1 is a potent reversible covalent Chst15 inhibitor. Chst15-IN-1 effectively inhibits chondroitin sulfate-E (CS-E) sulfation levels and other closely related glycosaminoglycans (GAG) sulfotransferases. Chst15-IN-1, as a selective sulfotransferase inhibitor, can diminish the inhibitory effects of chondroitin sulfate proteoglycans (CSPGs), and can be used for the stimulation of neuronal repair .
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1
1 Cited Publications
Cat. No.: HY-P5982
PTPσ Inhibitor, ISP is a PTPσ intracellular wedge domain mimetic peptide containing a TAT cell-penetrating domain, which acts as a PTPσ inhibitor. PTPσ Inhibitor, ISP binds to and inhibits PTPσ, thereby relieving CSPG-mediated axonal growth inhibition. PTPσ Inhibitor, ISP enhances CSPG degradation by promoting the secretion of Cathepsin B or MMP-2, and promotes DRG axonal growth, OPC migration and remyelination. PTPσ Inhibitor, ISP promotes nerve regeneration and improves sensory, motor and urinary functions in animal models of spinal cord injury, dorsal root injury and multiple sclerosis. PTPσ Inhibitor, ISP also increases the phosphorylation of ERK and AKT in colorectal cancer cells. PTPσ Inhibitor, ISP can be used in studies related to PTPσ/CSPG signaling, nerve regeneration, demyelinating diseases and RAS/ERK signaling .
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1
1 Cited Publications
Cat. No.: HY-N6612A
CAS No.: 207300-70-7
D-Glucuronic acid sodium salt monohydrate is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid sodium salt monohydrate activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid sodium salt monohydrate and its derivative glucurono-lactone can serve as liver detoxifiers, and its derivatives also possess anti-tumor activity .
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1
1 Cited Publications
Cat. No.: HY-P702616
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Versican core protein; VCAN; Chondroitin sulfate proteoglycan core protein 2; Chondroitin sulfate proteoglycan 2; Glial hyaluronate-binding protein; GHAP; Large fibroblast proteoglycan; PG-M; CSPG2
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P76059
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Hematopoietic proteoglycan core protein; Platelet proteoglycan core protein; P.PG; SRGN; PRG; PRG1
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P76058
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Hematopoietic proteoglycan core protein; Platelet proteoglycan core protein; P.PG; SRGN; PRG; PRG1
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P702525
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Mimecan; DKFZp586P2421; KSPG25; mimecan proteoglycan; Mimecan; OGN; OIF; OIFOG; osteoglycin; Osteoinductive factor; SLRR3A; SLRR3Acorneal keratan sulfate proteoglycan
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P74202
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Decorin; Bone proteoglycan II; PG-S2; PG40; DCN; SLRR1B
Species:  
Rat
Source:  
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1
1 Cited Publications
Cat. No.: HY-P7885
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuDecorin/PGS2, His; Decorin; Bone proteoglycan II; PG-S2; PG40; DCN; SLRR1B
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P80062
Synonyms: LHR antibody; BA-1 antibody; CD 44 antibody; CD44 antibody; CD44 antigen antibody; CD44 molecule (Indian blood group) antibody; CD44 molecule antibody; CD44_HUMAN antibody; CDw44 antibody; Cell surface glycoprotein CD44 antibody; chondroitin sulfate proteoglycan 8 antibody; CSPG8 antibody; ECMR-III antibody; Epican antibody; Extracellular matrix receptor III antibody; GP90 lymphocyte homing/adhesion receptor antibody; HCELL antibody; hematopoietic cell E- and L-selectin ligand antibody; Heparan sulfate proteoglycan antibody; Hermes antigen antibody; homing function and Indian blood group system antibody; HSA antibody; HUTCH-I antibody; HUTCH1 antibody; Hyaluronate receptor antibody; IN antibody; MC56 antibody; MDU2 antibody; MDU3 antibody

Host:  

Rabbit

Application:  

WB, IHC-P, FC

Reactivity:  

Human, Mouse

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