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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
rab27a inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "rab27a inhibitor" in MCE Product Catalog:
1
1 Cited Publications
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Research Areas:
Nexinhib20 is an inhibitor that targets the interactions of Rab27a-JFC1 (IC50: 2.6 μM) and Rac-1-GTP. Nexinhib20 can inhibit neutrophil exocytosis, adhesion, and β2 integrin activation, and has anti-inflammatory activity. Nexinhib20 can be used in the research of diseases such as systemic inflammation and myocardial ischemia-reperfusion injury .
Synonyms: EMD-15700
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Nitrefazole (EMD-15700) is an aldehyde dehydrogenase (ALDH) inhibitor. Nitrefazole specifically inhibits human liver ALDH I and human erythrocyte ALDH isozymes, but does not alter the activity of human liver ALDH II or human placental ALDH. Nitrefazole effectively promotes exosome secretion in prostate cancer cells by increasing the levels of Alix, nSMase2, Rab27a and p-ERK . Nitrefazole can be used in studies related to prostate cancer .
Cat. No.: HY-184152
CAS No.: 3129690-90-7
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IMP-2552 is a RAB27A/B inhibitor. IMP-2552 acts on the RAB27A/B effector protein-protein interaction, selectively modifying RAB27A/B-Cys123, but has no activity against RAB27A-Cys188. IMP-2552 can be used for the research of cancer .
Cat. No.: HY-184153
CAS No.: 3129691-65-9
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IMP-2958 is an inactive enantiomeric negative control probe with significantly reduced binding to RAB27A/B-Cys123.IMP-2958 serves as a negative control probe for off-target binding in phenotypic assays related to RAB27A/B studies.IMP-2958 functions as a control for stereoselective targeted covalent inhibitors of the RAB27-effector protein-protein interaction .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
