3 Results for "

rabbit reticulocyte lysate system

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "rabbit reticulocyte lysate system" in MCE Product Catalog:

Cat. No.: HY-139098
CAS No.: 62828-64-2
Synonyms: m7Gp3G
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

7-Methyl-diguanosine triphosphate (m7Gp3G) is an mRNA cap structure analog that inhibits in vitro protein synthesis by binding to the translation initiation complex. 7-Methyl-diguanosine triphosphate binds to eIF4E, promotes cap-dependent translation initiation, stabilizes mRNA, and acts as a translation enhancer. 7-Methyl-diguanosine triphosphate can be used to prepare synthetic capped RNA transcripts for studies related to mRNA translation, splicing, turnover, and intracellular transport .
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Cat. No.: HY-N13880
CAS No.: 69579-74-4
Adustin, an antifungal antibiotic, is a polypeptide with translation-inhibiting activity. Adustin inhibits translation in a cell-free rabbit reticulocyte lysate system with an IC50 of 0.34 μM .
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Cat. No.: HY-P11698
CAS No.: 476667-31-9
Research Areas:  

Cancer

Guanidino-G-Clamp-PNA is a highly efficient sequence-specific RNA binder and gene silencer. Guanidino-G-Clamp-PNA precisely targets such targets as miR-155 or transthyretin (TTR) mRNA through base pairing: the former regulates tumor-related signaling pathways by reducing microRNA activity, while the latter inhibits the translation of harmful proteins via steric hindrance. Guanidino-G-Clamp-PNA effectively stabilizes DNA/RNA duplexes, induces cancer cell apoptosis, and suppresses tumor growth. In addition, Guanidino-G-Clamp-PNA can be conjugated with targeting ligands to improve tissue-specific delivery and reduce in vivo adverse reactions, and it can also enhance the splicing regulation efficacy of other oligonucleotide platforms (such as PMO) when integrated into them. Guanidino-G-Clamp-PNA is applicable to the research of various diseases including diffuse large B-cell lymphoma and hereditary transthyretin-related amyloidosis .
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