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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
radical generation
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "radical generation" in MCE Product Catalog:
7
3
Category:
Microorganisms Vitis vinifera cv. Zalema Plants Vitaceae Disease Research Fields Inflammation/Immunology Saccharides Monosaccharides
Target:
3
3 Cited Publications
Synonyms: 2,2'-Azodiisobutyramidine dihydrochloride
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Research Areas:
AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis . AAPH decomposes at 37°C to generate an alkyl radical, is used as an initiator. In the presence of oxygen, these alkyl radicals will be converted to peroxyl radicals that can cause lipid peroxidation and loss of erythrocyte membrane integrity, which could ultimately lead to hemolysis .
2
2 Cited Publications
Cat. No.: HY-W013508
CAS No.: 106797-53-9
1
1 Cited Publications
Cat. No.: HY-W050000
CAS No.: 101328-85-2
Research Areas:
OR-1855, an active metabolite of Levosimendan (HY-14286), has effect on myometrial contractility. OR-1855 exerts anti-inflammatory effects by inhibiting IL-1β-induced ROS formation and NAD(P)H oxidase-dependent superoxide radical generation in HUVECs. OR-1855 inhibits IL-1β-induced phosphorylation p38 MAPK, ERK1/2, c-Jun and JNK in HUVECs. OR-1855 can be used for the study of inflammation .
Cat. No.: HY-W115721
CAS No.: 523-21-7
Synonyms: Sodium rhodizonate dibasic
Synonyms: Ro 19-6327
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Research Areas:
Lazabemide (Ro 19-6327) is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease .
Cat. No.: HY-B0871
CAS No.: 84087-01-4
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Quinclorac, an herbicide widely applied in agriculture, induces oxidative stress due to free radical generation and changes in the antioxidant defense system .
Cat. No.: HY-W145481A
CAS No.: 11078-30-1
Synonyms: Carob galactomannan
Cat. No.: HY-N3596
CAS No.: 84575-10-0
Synonyms: Aquillochin
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Cat. No.: HY-14202
CAS No.: 103878-83-7
Synonyms: Ro 19-6327 hydrochloride
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Research Areas:
Lazabemide hydrochloride (Ro 19-6327 hydrochloride) is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease .
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Cat. No.: HY-42682S1
CAS No.: 478518-54-6
Synonyms: D-Galactosamine-13C hydrochloride
Cat. No.: HY-116778
CAS No.: 51982-36-6
Category:
Target:
Cat. No.: HY-U00005
CAS No.: 145600-69-7
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AD 0261 is a radical scavenger which displays strong inhibitory action on the generation of lipid peroxides and superoxide anions.
Cat. No.: HY-N8447
CAS No.: 1891097-17-8
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Cat. No.: HY-119092
CAS No.: 89194-77-4
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Bisaramil is an orally active antiarrhythmic agent. Bisaramil exerts concentration dependent inhibitory effect on PMA-stimulated free radical generation and prolonged the time lag concentration dependently .
Cat. No.: HY-W686216
CAS No.: 312611-92-0
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Research Areas:
VK-28 is a blood-brain barrier-permeable iron chelator. VK-28 inhibits mitochondrial membrane lipid peroxidation and the iron-dependent generation of reactive hydroxyl radicals. VK-28 exhibits neuroprotective activity and protects rats against 6-OHDA-induced striatal dopaminergic damage. VK-28 can be used in studies related to Parkinson's disease .
Cat. No.: HY-108998
CAS No.: 96480-44-3
Target:
Research Areas:
Bisaramil hydrochloride is an antiarrhythmic compound with activity in inhibiting free radical generation. Bisaramil hydrochloride directly blocks sodium currents and exhibits enhanced sodium channel blocking ability. Bisaramil hydrochloride inhibits isoproterenol-induced slow calcium action potentials in cardiomyocytes. Bisaramil hydrochloride reduces heart rate and prolongs the PR, QRS, and QT intervals in the electrocardiogram, showing blocking effects on sodium and potassium channels. Bisaramil hydrochloride reduces cardiac conduction velocity, increases the threshold current for capture and atrial fibrillation, and prolongs the effective refractory period. Bisaramil hydrochloride reduces ventricular arrhythmias and eliminates mortality caused by ventricular fibrillation in ischemic rat hearts .
Cat. No.: HY-N9086A
CAS No.: 70460-58-1
Synonyms: 5,7,4'-Trihydroxy-6-methylflavanone
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
