country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-116778

Copy Link Print Information

Prostaglandin G2

Customer Review

Based on 1 Customer Validation

Prostaglandin G2 is a prostaglandin peroxide. Prostaglandin G2 acts as a precursor for thromboxane A₂ production, inducing platelet aggregation and serotonin release. Prostaglandin G2 also induces cerebral arteriole injury in anesthetized cats via the generation of reactive oxygen free radicals, triggering persistent vasodilation, reduced reactivity to hypocapnia, and endothelial damage. Prostaglandin G2 can be used in studies related to cerebral arteriole injury.

For research use only. We do not sell to patients.

Purity: 99.9%
CAS No.: 51982-36-6
Formula: C₂₀H₃₂O₆
Molecular Weight:368.46

Storage:

Solution, -20°C, 2 years

Prostaglandin G2 Chemical Structure

CAS No.: 51982-36-6

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Prostaglandin G2 (0.6-1 μg) incubated with Indomethacin (HY-14397)-pretreated washed human platelets generates an unstable rabbit aorta contracting factor (thromboxane A₂) with a half-life of 34 sec at 37 °C that induces strong contraction of isolated rabbit aorta strips^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Prostaglandin G2 (10 μg/mL; local administration under cranial window; single exposure for 15 min) induces cerebral arteriole injury in anesthetized cats^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Domestic cats (anesthetized with pentobarbital)^[2]
Dosage:

10 μg/mL
Administration:

topical application under cranial window; single 15-minute exposure
Result:

Induced 30% residual arteriolar dilation (percent of control) 1 hour after removal.
Reduced arteriolar diameter decrease in response to arterial hypocapnia from 12% to 8% of control.
Caused 13.3 endothelial lesions per 2100 μm² of pial arteriole surface.

Chemical Information

CAS No. 51982-36-6
Appearance Liquid
Molecular Weight 368.46
Formula C₂₀H₃₂O₆
Color Colorless to light yellow
SMILES

CCCCC[C@H](OO)/C=C/[C@@H]1[C@H]([C@]2([H])C[C@@]1([H])OO2)C/C=C\CCCC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
SDS (605 KB)
- English - EN (605 KB)
- Français - FR (605 KB)
- Deutsch - DE (605 KB)
- Norwegian - NO (605 KB)
- Español - ES (605 KB)
- Swedish - SV (605 KB)
- Italian - IT (605 KB)
- Korean - KR (605 KB)
- Portuguese - PT (605 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hamberg M, et al. Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci U S A. 1975;72(8):2994-2998. [Content Brief]

[2]. Kontos H A, et al. Cerebral arteriolar damage by arachidonic acid and prostaglandin G2. Science, 1980, 209(4462): 1242-1245.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

Get Quote In-stock