89194-77-4
89194-77-4
Chemical Structure
Bisaramil
- CAS No.: 89194-77-4
- Formula:C17H23ClN2O2
- Molecular Weight:322.83
IUPAC Name: (1R,5S,9r)-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]nonan-9-yl 4-chlorobenzoate
InChIKey: PMCPYLGCPSNSLS-FOLVSLTJSA-N
SMILES: O=C(C1=CC=C(Cl)C=C1)O[C@]2([C@H]3CN(CC)C[C@@H]2CN(C)C3)[H]
Biological Activity: Bisaramil is an orally active antiarrhythmic agent. Bisaramil exerts concentration dependent inhibitory effect on PMA-stimulated free radical generation and prolonged the time lag concentration dependently[1][2].
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Bisaramil | Bisaramil is an orally active antiarrhythmic agent. Bisaramil exerts concentration dependent inhibitory effect on PMA-stimulated free radical generation and prolonged the time lag concentration dependently. | |||||||||||||||||||||
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References
- [1]. M K Pugsley, et al. Effects of bisaramil, a novel class I antiarrhythmic agent, on heart, skeletal muscle and brain Na+ channels. Eur J Pharmacol. 1998 Jan 19;342(1):93-104. [Content Brief]
- [2]. M Paróczai, et al. Bisaramil and antiarrhythmics as inhibitors of free radical generation. Pharmacol Res. 1997 Apr;35(4):279-85. [Content Brief]
Keywords
