8 Results for "

recombinant human TNF-α

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "recombinant human TNF-α" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-101913
CAS No.: 2205034-18-8
Purity:  99.74%
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

IL-17A antagonist 1 is an interleukin-17A (IL-17A) antagonist with an IC50 of 1.14 μM and a Kd of 0.66 μM. IL-17A antagonist 1 binds specifically and exclusively to the IL-17A homodimer at its central dimer interface pocket, induces a large conformational change that widens the pocket, and disrupts the IL-17A/IL-17RA interaction. IL-17A antagonist 1 does not bind to IL-17F or IL-17RA .
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Cat. No.: HY-P99252
CAS No.: 1116433-11-4
Synonyms: Anti-human CD6 recombinant Antibody

Target:  

CD6

Research Areas:  

Infection Inflammation/Immunology

Itolizumab (Anti-Human CD6 Recombinant Antibody) is a humanized recombinant anti-CD6 monoclonal antibody (MAb) targeting the extracellular SRCR distal domain 1 of CD6. Itolizumab reduces T-cell proliferation and inhibits the production of pro-inflammatory cytokines, such as INF-γ, TNFα and IL-6. Itolizumab can be used in the research of psoriasis, rheumatoid arthritis (RA), COVID-19 .
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Cat. No.: HY-P99830
CAS No.: 1227158-72-6
Synonyms: KH902
Conbercept (KH902) is a recombinant fusion protein composed of VEGFR-1 (second domain) and VEGFR-2 (third and fourth domains) regions fused to human IgG1 Fc. Conbercept is a VEGF inhibitor (IC50 = 8.8 pM) and is a soluble receptor decoy that blocks all isoforms of VEGF-A (Kd = 0.5 pM), VEGF-B (Kd = 8 pM), VEGF-C, and PlGF (Kd = 5 pM). Conbercept has anti-inflammatory effects, can lower the levels of VEGF, TNF-α and IL-6, and reduce the infiltration of inflammatory cells. Conbercept decreases tumor growth in several oncology studies. Conbercept can be used for various eye diseases such as polypoidal choroidal vasculopathy (PCV), diabetic macular edema (DME) and pathologic myopia choroidal neovascularization (pmCNV) .
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Cat. No.: HY-P99782
CAS No.: 2055118-96-0

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Opinercept is a recombinant fusion protein comprising an TNFRSF1B fused to a human IgG1 Fc . Opinercept is a tumor necrosis factor-alpha (TNF-alpha) inhibitor. Opinercept can be used for the research of rheumatoid arthritis (RA) .
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Cat. No.: HY-13478
CAS No.: 928344-12-1
AS1940477 (Compound 3f) is an orally active p38 MAPK inhibitor. AS1940477 inhibits the enzymatic activity of recombinant p38α and β isoforms. AS1940477 inhibits the production of pro-inflammatory cytokines (including TNFα, IL-1β, and IL-6) in human synovial interstitial cells and animal models of inflammation. AS1940477 can be used in research on inflammatory diseases .
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Cat. No.: HY-101913R
CAS No.: 2205034-18-8
IL-17A antagonist 1 (Standard) is the analytical standard of IL-17A antagonist 1 (HY-101913). This product is intended for research and analytical applications. IL-17A antagonist 1 is an interleukin-17A (IL-17A) antagonist with an IC50 of 1.14 μM and a Kd of 0.66 μM. IL-17A antagonist 1 binds specifically and exclusively to the IL-17A homodimer at its central dimer interface pocket, induces a large conformational change that widens the pocket, and disrupts the IL-17A/IL-17RA interaction. IL-17A antagonist 1 does not bind to IL-17F or IL-17RA .
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Cat. No.: HY-N20703
CAS No.: 163527-00-2
Resveratrol 12-C-β-glucopyranoside is a stilbene-type natural secondary metabolite. Resveratrol 12-C-β-glucopyranoside has the potential to target TNF-α, TGF-β1, and PPAR-α. As one of the core active components of MESR, Resveratrol 12-C-β-glucopyranoside exerts hepatoprotective, anti-inflammatory, and antioxidant effects in a rat liver injury model induced by Isoniazid (HY-B0329). Resveratrol 12-C-β-glucopyranoside can be used for studies related to drug-induced liver injury .
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Cat. No.: HY-186214
CAS No.: 3034837-81-2
Research Areas:  

Inflammation/Immunology

PDE4-IN-36 is a phosphodiesterase 4 (PDE4) inhibitor with significant inhibitory activity at 10 μM. PDE4-IN-36 can be used in the research of psoriasis and atopic dermatitis .
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