Resveratrol 12-C-β-glucopyranoside
Resveratrol 12-C-β-glucopyranoside is a stilbene-type natural secondary metabolite. Resveratrol 12-C-β-glucopyranoside has the potential to target TNF-α, TGF-β1, and PPAR-α. As one of the core active components of MESR, Resveratrol 12-C-β-glucopyranoside exerts hepatoprotective, anti-inflammatory, and antioxidant effects in a rat liver injury model induced by Isoniazid (HY-B0329). Resveratrol 12-C-β-glucopyranoside can be used for studies related to drug-induced liver injury.
For research use only. We do not sell to patients.
- CAS No.: 163527-00-2
- Formula: C20H22O8
- Molecular Weight:390.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Resveratrol 12-C-β-glucopyranoside shows high binding affinity to recombinant human TNF-α (-9.9 kcal/mol) and TGF-β1 (-10.0 kcal/mol), as well as moderate binding affinity to PPAR-α according to molecular docking results, which suggests it may exert potential hepatoprotective effects via regulating these pivotal targets[1].
Resveratrol 12-C-β-glucopyranoside is a compound isolated from the stem bark of Shorea hemsleyana, with a C-β-glucopyranosyl group attached at the C-12 position of Resveratrol (HY-16561)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 163527-00-2
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Molecular Weight 390.38
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Formula C20H22O8
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SMILES
OC1=C([C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)C(O)=CC(/C=C/C3=CC=C(C=C3)O)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Samantaray B, et al. Hepatoprotective Mechanism of Shorea Robusta Gaertn. f. Against Isoniazid-induced Hepatotoxicity by Targeting TNF-α, TGF-β1, and PPAR-α: Insights from Computational Profiling To Immunohistochemical Confirmation. Cell biochemistry and biophysics. 2026 Jun;84(2):2209-2239. [Content Brief]
[2]. Ito T, et al. Stilbenoids isolated from stem bark of Shorea hemsleyana. Chemical & pharmaceutical bulletin. 2000 Jul;48(7):1001-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Resveratrol 12-C-β-glucopyranoside Related Classifications
HY-N20703 Related Classifications
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