Search Result

Results for "

reproductive organs

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Anaplastic lymphoma kinase (ALK) (1) Apoptosis (2) Bcl-2 Family (1) Biochemical Assay Reagents (3) Caspase (2) Cytochrome P450 (1) Drug Intermediate (1) Environmental Pollutants (2) Estrogen Receptor/ERR (2) Ferroptosis (3) GnRH Receptor (1) Isotope-Labeled Compounds (2) p38 MAPK (1) Parasite (1) PI3K (1) Reactive Oxygen Species (ROS) (4) Reference Standards (2) SOD (1) TGF-beta/Smad (1) TGF-β Receptor (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (2) Endocrinology (5) Infection (1) Inflammation/Immunology (4) Metabolic Disease (4) Neurological Disease (3)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Antioxidants (1)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1066

Butylhydroxyanisole 5 Publications Verification Butylated hydroxyanisole; E320	Environmental Pollutants Reactive Oxygen Species (ROS) Ferroptosis	Neurological Disease Inflammation/Immunology
Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .

HY-B1012

Quinestrol W-3566	Estrogen Receptor/ERR Cytochrome P450 GnRH Receptor	Metabolic Disease Endocrinology
Quinestrol (W-3566) is an orally effective synthetic estrogen compound that acts on CYP3A4, CYP1A2, and GnRH. Quinestrol interferes with GnRH release and disrupts the hypothalamic-pituitary-ovarian axis. Quinestrol downregulates the gene expression of follicle-stimulating hormone β and luteinizing hormone β, induces oxidative stress, damages reproductive organs, reduces sperm density and motility, increases sperm malformation rate, and alters the levels of sex hormones such as testosterone, luteinizing hormone, estradiol, and progesterone. Quinestrol can be used in studies related to reproductive function regulation .

HY-W075770

Nickel(II) oxide Nickel monoxide	Environmental Pollutants Apoptosis Reactive Oxygen Species (ROS) Caspase TGF-beta/Smad p38 MAPK Akt PI3K	Infection Metabolic Disease Cancer
Nickel(II) oxide (nickel monoxide) is a chemical warfare agent that can enter the body through the respiratory tract and other routes, distributing to organs such as the lungs and testes. The nanoparticle form of nickel(II) oxide (NiO NPs) exhibits antibacterial, anti-leishmanial, anti-diabetic, and anti-cancer activities. NiO NPs can be activated by ultraviolet and visible light, generating reactive oxygen species (ROS). Nickel(II) oxide induces oxidative stress by generating reactive oxygen species, activating the TGF-β1-mediated MAPK and PI3K/AKT pathways, disrupting the MMPs/TIMPs balance, and upregulating the expression of inflammatory factors (IL-1β, IL-6) and apoptosis-related molecules (Bax, caspase-3, p53), while inhibiting the activity of the anti-apoptotic molecule Bcl-2. Nickel(II) oxide induces cytotoxicity, promotes fibrosis, triggers inflammatory responses, and causes apoptosis. Nickel(II) oxide can be applied in research on the safety assessment of nanomaterials, such as in the context of pulmonary fibrosis and reproductive system toxicity .

HY-N7681

Taxifolin 7-O-β-D-glucoside 1 Publications Verification Taxifolin 7-O-glucoside	Biochemical Assay Reagents	Inflammation/Immunology
Taxifolin 7-O-β-D-glucoside (Taxifolin 7-O-glucoside) is a flavonol and active antioxidant that can be isolated from Scutellaria baicalensis. Taxifolin 7-O-β-D-glucoside participates in pathogen defense and ultraviolet damage protection in the seed coat during seed germination of Scutellaria baicalensis .

HY-B1066R

Butylhydroxyanisole (Standard) Butylated hydroxyanisole (Standard); E320 (Standard)	Reference Standards Reactive Oxygen Species (ROS) Ferroptosis	Neurological Disease Inflammation/Immunology
Butylhydroxyanisole (Standard) is the analytical standard of Butylhydroxyanisole. This product is intended for research and analytical applications. Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .

HY-W585856

Bisphenol A (3-chloro-2-hydroxypropyl)glycidyl ether	Drug Intermediate	Others
Bisphenol A (3-chloro-2-hydroxypropyl) glycidyl ether is a chlorinated derivative that is released during heat treatment of food cans, bulk storage containers, and food containers. Bisphenol A (3-chloro-2-hydroxypropyl) glycidyl ether is an endocrine disruptor that affects reproductive organs and brain development.

HY-171248

CDD-1115	Anaplastic lymphoma kinase (ALK)	Cardiovascular Disease Endocrinology
CDD-1115 is a potent, selective inhibitor of BMPR2 with IC₅₀ of 1.8 nM, K_iapp of 6.2 nM. CDD-1115 inhibits bone morphogenetic protein (BMP)-mediated gene expression. BMP controls cellular processes across many tissue types, including the kidney, skeletal muscle, heart, and reproductive organs. BMP induces ectopic bone formation .

HY-171249

CDD-1431	TGF-β Receptor	Cardiovascular Disease Endocrinology
CDD-1431 is a low-nanomolar selective kinase inhibitors of BMPR2, with K_iapp value of 20.6 nM. CDD-1431 suppresses BRE-reporter activity, with an IC₅₀ of 4.87 μM. BMP controls cellular processes across many tissue types, including the kidney, skeletal muscle, heart, and reproductive organs. BMP induces ectopic bone formation .

HY-W102684

N,N-Dicyclohexyl-2-benzothiazolesulfenamide	Biochemical Assay Reagents	Others
N,N-Dicyclohexyl-2-benzothiazolesulfenamide is a compound with reproductive and developmental toxicity that can affect body weight gain, reproductive organ weight, and multiple reproductive and developmental indicators in rats.

HY-21191S

Perfluorobutanesulfonic acid-13C3 sodium PFBS-¹³C₃ sodium	Isotope-Labeled Compounds Biochemical Assay Reagents Parasite	Metabolic Disease
Perfluorobutanesulfonic acid- ¹³C₃ (PFBS- ¹³C₃) sodium is the ¹³C-labeled Perfluorobutanesulfonic acid (HY-21191). Perfluorobutanesulfonic acid is a surfactant that can disrupt the development of pancreatic organs and lipid metabolism regulation in zebrafish. Perfluorobutanesulfonic acid can harm the reproductive ability of nematodes (Caenorhabditis elegans) and alter the physiological functions of their offspring .

HY-178425S

Butylhydroxyanisole-d24 Butylated hydroxyanisole-d₂₄; E320-d₂₄	Isotope-Labeled Compounds Ferroptosis Reactive Oxygen Species (ROS)	Neurological Disease Inflammation/Immunology
Butylhydroxyanisole-d₂₄ (Butylated hydroxyanisole-d₂₄) is the deuterium labeled Butylhydroxyanisole (HY-B1066). Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .

HY-B1012R

Quinestrol (Standard) W-3566 (Standard)	Reference Standards Estrogen Receptor/ERR	Metabolic Disease Endocrinology
Quinestrol (Standard) is the analytical standard of Quinestrol (HY-B1012). This product is intended for research and analytical applications. Quinestrol (W-3566) is an orally effective synthetic estrogen compound that acts on CYP3A4, CYP1A2, and GnRH. Quinestrol interferes with GnRH release and disrupts the hypothalamic-pituitary-ovarian axis. Quinestrol downregulates the gene expression of follicle-stimulating hormone β and luteinizing hormone β, induces oxidative stress, damages reproductive organs, reduces sperm density and motility, increases sperm malformation rate, and alters the levels of sex hormones such as testosterone, luteinizing hormone, estradiol, and progesterone. Quinestrol can be used in studies related to reproductive function regulation .

HY-N18905

α-D-Glucosyl hesperidin	Apoptosis Bcl-2 Family Caspase SOD	Endocrinology
α-D-Glucosyl hesperidin is an orally effective structural modification derivative of Hesperidin (HY-15337) with anti-apoptotic (apoptosis) and antioxidant activities. α-D-Glucosyl hesperidin upregulates the expression of the Bcl-2 gene, while downregulating the expressions of the Bax and caspase-3 genes. α-D-Glucosyl hesperidin increases total antioxidant capacity, SOD and catalase levels, and decreases malondialdehyde and glutathione levels. α-D-Glucosyl hesperidin improves sperm motility, viability and plasma membrane function, while restoring reproductive organ weight and seminiferous tubule structure. α-D-Glucosyl hesperidin increases fertility index and exerts a synergistic protective effect with Proanthocyanidins (HY-N0794) in male rats with testicular ischemia-reperfusion injury. α-D-Glucosyl hesperidin can be used in the research of testicular ischemia-reperfusion injury .

Cat. No.	Product Name

HY-L239

Steroid Hormones Library	70 compounds
Steroid hormones (also known as steroidal hormones) are a class of tetracyclic aliphatic hydrocarbon compounds derived from cholesterol. Typical representatives of steroid hormones include cortisol, aldosterone, testosterone, estradiol, among others. These hormones serve diverse regulatory functions within the body. For instance, aldosterone helps maintain the homeostasis of extracellular fluid volume and circulating blood volume; testosterone and estradiol primarily promote the development and maturation of male and female reproductive organs and regulate reproductive functions. MCE designs a unique collection of 70 steroid hormones. This library can be used for research related to metabolic or immune diseases, investigations into the mechanisms of action of nuclear receptor signaling pathways, as well as identification and quantitative analysis in metabolomics studies.

Steroid Hormones Library

70 compounds

Steroid hormones (also known as steroidal hormones) are a class of tetracyclic aliphatic hydrocarbon compounds derived from cholesterol. Typical representatives of steroid hormones include cortisol, aldosterone, testosterone, estradiol, among others. These hormones serve diverse regulatory functions within the body. For instance, aldosterone helps maintain the homeostasis of extracellular fluid volume and circulating blood volume; testosterone and estradiol primarily promote the development and maturation of male and female reproductive organs and regulate reproductive functions.

MCE designs a unique collection of 70 steroid hormones. This library can be used for research related to metabolic or immune diseases, investigations into the mechanisms of action of nuclear receptor signaling pathways, as well as identification and quantitative analysis in metabolomics studies.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7681

Taxifolin 7-O-β-D-glucoside 1 Publications Verification Taxifolin 7-O-glucoside	Flavanonols Structural Classification Flavonoids Classification of Application Fields Cercis chinensis Bunge Other Diseases Phenols Polyphenols Plants Compositae Disease Research Fields Source Classification	Biochemical Assay Reagents
Taxifolin 7-O-β-D-glucoside (Taxifolin 7-O-glucoside) is a flavonol and active antioxidant that can be isolated from Scutellaria baicalensis. Taxifolin 7-O-β-D-glucoside participates in pathogen defense and ultraviolet damage protection in the seed coat during seed germination of Scutellaria baicalensis .

HY-N18905

α-D-Glucosyl hesperidin	Structural Classification Flavonoids Flavonones Endogenous metabolite Source Classification	Apoptosis Bcl-2 Family Caspase SOD
α-D-Glucosyl hesperidin is an orally effective structural modification derivative of Hesperidin (HY-15337) with anti-apoptotic (apoptosis) and antioxidant activities. α-D-Glucosyl hesperidin upregulates the expression of the Bcl-2 gene, while downregulating the expressions of the Bax and caspase-3 genes. α-D-Glucosyl hesperidin increases total antioxidant capacity, SOD and catalase levels, and decreases malondialdehyde and glutathione levels. α-D-Glucosyl hesperidin improves sperm motility, viability and plasma membrane function, while restoring reproductive organ weight and seminiferous tubule structure. α-D-Glucosyl hesperidin increases fertility index and exerts a synergistic protective effect with Proanthocyanidins (HY-N0794) in male rats with testicular ischemia-reperfusion injury. α-D-Glucosyl hesperidin can be used in the research of testicular ischemia-reperfusion injury .

Cat. No.	Product Name	Chemical Structure

HY-21191S

Perfluorobutanesulfonic acid-13C3 sodium
Perfluorobutanesulfonic acid- ¹³C₃ (PFBS- ¹³C₃) sodium is the ¹³C-labeled Perfluorobutanesulfonic acid (HY-21191). Perfluorobutanesulfonic acid is a surfactant that can disrupt the development of pancreatic organs and lipid metabolism regulation in zebrafish. Perfluorobutanesulfonic acid can harm the reproductive ability of nematodes (Caenorhabditis elegans) and alter the physiological functions of their offspring .

Perfluorobutanesulfonic acid-13C3 sodium

Perfluorobutanesulfonic acid- ¹³C₃ (PFBS- ¹³C₃) sodium is the ¹³C-labeled Perfluorobutanesulfonic acid (HY-21191). Perfluorobutanesulfonic acid is a surfactant that can disrupt the development of pancreatic organs and lipid metabolism regulation in zebrafish. Perfluorobutanesulfonic acid can harm the reproductive ability of nematodes (Caenorhabditis elegans) and alter the physiological functions of their offspring .

HY-178425S

Butylhydroxyanisole-d24
Butylhydroxyanisole-d₂₄ (Butylated hydroxyanisole-d₂₄) is the deuterium labeled Butylhydroxyanisole (HY-B1066). Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .

Butylhydroxyanisole-d24

Butylhydroxyanisole-d₂₄ (Butylated hydroxyanisole-d₂₄) is the deuterium labeled Butylhydroxyanisole (HY-B1066). Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .

Cat. No.	Product Name		Classification