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secoiridoid glycoside

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) AMPK (2) Apoptosis (2) MMP (1) NO Synthase (1) Reference Standards (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (1) Metabolic Disease (3)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2447

Amarogentin 2 Publications Verification	AMPK Apoptosis	Metabolic Disease Cancer
Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

HY-N8837

Trifloroside	MMP	Metabolic Disease
Trifloroside is a secoiridoid glycoside with antioxidant effects. Trifloroside induces osteogenic effects through osteoblast differentiation, adhesion, migration, and mineral apposition. Trifloroside has the potential for osteoblast-mediated bone diseases research .

HY-N7895

Secologanic acid 1 Publications Verification	NO Synthase Akt	Inflammation/Immunology
Secologanic acid is a secoiridoid glycoside. Secologanic acid inhibits NO production, the relative expression of AKT and p-AKT. Secologanic acid shows anti-inflammatory activity .

HY-N5094

6'-O-β-Apiofuranosylsweroside	Others	Others
6'-O-β-Apiofuranosylsweroside is a secoiridoid glycoside that can be isolated from the leaves of Lonicera angustifolia Wall .

HY-N3839

epi-Vogeloside 7-epi-Vogeloside; Nervoside; Epivogeloside	Others	Others
epi-Vogeloside is a secoiridoid glycoside and a iridoid glucoside, which can be isolated from Lonicera japonica Thunb .

HY-N18309

Jasnudifloside A	Others	Others
Jasnudifloside A (Compound 1) is a secoiridoid glycoside. Jasnudifloside A is isolated from the leaves and stems of Jasminum nudiflorum .

HY-N2447R

Amarogentin (Standard)	Reference Standards AMPK Apoptosis	Metabolic Disease Cancer
Amarogentin (Standard) is the analytical standard of Amarogentin. This product is intended for research and analytical applications. Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

Amarogentin 2 Publications Verification	Gentiana scabra Bunge Iridoids Classification of Application Fields Terpenoids Gentianaceae Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	AMPK Apoptosis
Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

Trifloroside	Structural Classification Gentiana scabra Bunge Iridoids Terpenoids Gentianaceae Plants Source Classification	MMP
Trifloroside is a secoiridoid glycoside with antioxidant effects. Trifloroside induces osteogenic effects through osteoblast differentiation, adhesion, migration, and mineral apposition. Trifloroside has the potential for osteoblast-mediated bone diseases research .

Secologanic acid 1 Publications Verification	other families Iridoids Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification	NO Synthase Akt
Secologanic acid is a secoiridoid glycoside. Secologanic acid inhibits NO production, the relative expression of AKT and p-AKT. Secologanic acid shows anti-inflammatory activity .

6'-O-β-Apiofuranosylsweroside	Caprifoliaceae Iridoids Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification Lonicera angustifolia Wall. ex DC.	Others
6'-O-β-Apiofuranosylsweroside is a secoiridoid glycoside that can be isolated from the leaves of Lonicera angustifolia Wall .

epi-Vogeloside 7-epi-Vogeloside; Nervoside; Epivogeloside	Caprifoliaceae Iridoids Lonicera japonica Thunb. Terpenoids Plants Source Classification	Others
epi-Vogeloside is a secoiridoid glycoside and a iridoid glucoside, which can be isolated from Lonicera japonica Thunb .

Jasnudifloside A	Structural Classification Iridoids Oleaceae Jasminum nudiflorum Lindl. Terpenoids Plants Source Classification	Others
Jasnudifloside A (Compound 1) is a secoiridoid glycoside. Jasnudifloside A is isolated from the leaves and stems of Jasminum nudiflorum .

Amarogentin (Standard)	Structural Classification Gentiana scabra Bunge Iridoids Terpenoids Gentianaceae Phenols Polyphenols Plants Source Classification	Reference Standards AMPK Apoptosis
Amarogentin (Standard) is the analytical standard of Amarogentin. This product is intended for research and analytical applications. Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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secoiridoid glycoside

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