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skincare products

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Bacterial (4) Drug Intermediate (1) Environmental Pollutants (1) Fungal (1) Histone Demethylase (1) NF-κB (1) Reference Standards (2)
By Research Areas:	Infection (3) Inflammation/Immunology (2) Metabolic Disease (2)

Inhibitors & Agonists

Screening Libraries

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5275

Tripeptide-41 CG-Lipoxyn	NF-κB Histone Demethylase	Metabolic Disease
Tripeptide-41 (CG-Lipoxyn) is a signal peptide. Tripeptide-41 activates the NF-kB signaling pathway, inhibits the expression of C/EBP and increases cAMP. Tripeptide-41 is an important intracellular signaling factor that causes lipolysis by promoting the hydrolysis of lipids into triglycerides. Tripeptide-41 can be used in cosmetics that targets fat accumulation .

HY-107784R

Ectoine (Standard)	Reference Standards Bacterial	Inflammation/Immunology
Ectoine (Standard) is the analytical standard of Ectoine. This product is intended for research and analytical applications. Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis .

HY-Y0335R

1,3-Dihydroxyacetone (Standard) Dihydroxyacetone (Standard)	Reference Standards Drug Intermediate Bacterial Antibiotic	Infection
1,3-Dihydroxyacetone (Standard) is the analytical standard of 1,3-Dihydroxyacetone. This product is intended for research and analytical applications. 1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227) .

HY-W133973

Jasmine absolute Jasmine oil Jasminum grandiflorum L	Others	Others
Jasmine absolute is an aromatic substance extracted from jasmine and is widely used in perfumes, skincare products, and aromatherapy.

HY-N19069

Eugenia jambolana extract	Bacterial	Infection Metabolic Disease Inflammation/Immunology
Eugenia jambolana extract, commonly known as jamun or black plum, is derived from the fruit of the Eugenia jambolana tree, native to South Asia. The active compounds in jamun extract include anthocyanins, flavonoids, alkaloids, and tannins, which contribute to its antioxidant, anti-inflammatory, and antimicrobial properties. Jamun extract is most known for its blood sugar-lowering effects, making it popular in traditional medicine for managing diabetes. It is commonly used in supplements, traditional remedies, and skincare products due to its wide range of health benefits.

HY-W040536

DMDM hydantoin Dimethyloldimethyl hydantoin	Environmental Pollutants Bacterial Fungal	Infection
DMDM hydantoin (Glydant) is an allergen and formaldehyde-releasing preservative. DMDM hydantoin releases formaldehyde under regulation by multiple factors and with enhanced release in alkaline environments. DMDM hydantoin induces allergic contact dermatitis via type-IV delayed hypersensitivity, either directly or through released formaldehyde. DMDM hydantoin is a broad-spectrum preservative that is effective against fungi, yeast, and gram-positive and gram-negative bacteria. DMDM hydantoin can be used in cosmetics industry production research (e.g., shampoos, hairsprays, and skincare products) and can be used for research on allergic contact dermatitis .

Cat. No.	Product Name

HY-L221

Cosmetic Ingredient Compound Library	622 compounds
Cosmetics are complex mixtures formulated through the rational blending and processing of various natural, synthetic, or extracted raw materials. The ingredients used in cosmetics are diverse in type and functionality. Based on their properties and applications, cosmetic ingredients can generally be classified into two main categories: base materials and auxiliary ingredients. The former constitutes the primary component of cosmetics, accounting for a significant proportion in formulations and serving as the key functional substances. Auxiliary ingredients, on the other hand, play roles in shaping the product, ensuring stability, or imparting color, fragrance, and other specific characteristics.Establishing a systematic ingredient database is of great significance for cosmetic research and development. By analyzing the physicochemical properties (such as oil-water partition coefficients and molecular weight distribution), biological activity mechanisms (such as antioxidant pathways and cellular signaling regulation), and compatibility of ingredients, the database can provide precise guidance for formulation design. This approach helps shorten the development cycle of cosmetic/skincare products and reduces trial-and-error costs. MCE offers 622 types of cosmetic ingredient compounds, including antioxidants, humectants, emulsifiers, film-forming agents, and more.

Cosmetic Ingredient Compound Library

622 compounds

Cosmetics are complex mixtures formulated through the rational blending and processing of various natural, synthetic, or extracted raw materials. The ingredients used in cosmetics are diverse in type and functionality. Based on their properties and applications, cosmetic ingredients can generally be classified into two main categories: base materials and auxiliary ingredients. The former constitutes the primary component of cosmetics, accounting for a significant proportion in formulations and serving as the key functional substances. Auxiliary ingredients, on the other hand, play roles in shaping the product, ensuring stability, or imparting color, fragrance, and other specific characteristics.Establishing a systematic ingredient database is of great significance for cosmetic research and development. By analyzing the physicochemical properties (such as oil-water partition coefficients and molecular weight distribution), biological activity mechanisms (such as antioxidant pathways and cellular signaling regulation), and compatibility of ingredients, the database can provide precise guidance for formulation design. This approach helps shorten the development cycle of cosmetic/skincare products and reduces trial-and-error costs.

MCE offers 622 types of cosmetic ingredient compounds, including antioxidants, humectants, emulsifiers, film-forming agents, and more.

Cat. No.	Product Name	Target	Research Area

HY-P5275

Tripeptide-41 CG-Lipoxyn	NF-κB Histone Demethylase	Metabolic Disease
Tripeptide-41 (CG-Lipoxyn) is a signal peptide. Tripeptide-41 activates the NF-kB signaling pathway, inhibits the expression of C/EBP and increases cAMP. Tripeptide-41 is an important intracellular signaling factor that causes lipolysis by promoting the hydrolysis of lipids into triglycerides. Tripeptide-41 can be used in cosmetics that targets fat accumulation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-107784R

Ectoine (Standard)	Structural Classification Microorganisms Amino acids Source Classification	Reference Standards Bacterial
Ectoine (Standard) is the analytical standard of Ectoine. This product is intended for research and analytical applications. Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis .

HY-Y0335R

1,3-Dihydroxyacetone (Standard) Dihydroxyacetone (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Drug Intermediate Bacterial Antibiotic
1,3-Dihydroxyacetone (Standard) is the analytical standard of 1,3-Dihydroxyacetone. This product is intended for research and analytical applications. 1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227) .

HY-W133973

Jasmine absolute Jasmine oil Jasminum grandiflorum L	Structural Classification Oleaceae Extract Jasminum sambac (L.) Aiton Plants Source Classification	Others
Jasmine absolute is an aromatic substance extracted from jasmine and is widely used in perfumes, skincare products, and aromatherapy.

HY-N19069

Eugenia jambolana extract	Structural Classification Extract	Bacterial
Eugenia jambolana extract, commonly known as jamun or black plum, is derived from the fruit of the Eugenia jambolana tree, native to South Asia. The active compounds in jamun extract include anthocyanins, flavonoids, alkaloids, and tannins, which contribute to its antioxidant, anti-inflammatory, and antimicrobial properties. Jamun extract is most known for its blood sugar-lowering effects, making it popular in traditional medicine for managing diabetes. It is commonly used in supplements, traditional remedies, and skincare products due to its wide range of health benefits.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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