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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
small molecular peptides
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "small molecular peptides" in MCE Product Catalog:
Synonyms: BI 1029539; GS-248; OX-MPI
Target:
Vipoglanstat (BI 1029539), a carboxamide, is a potent and selective, non-peptide and orally active small molecular inhibitor of human prostaglandin E synthase 1 (mPGES-1). Vipoglanstat also has anti-inflammatory activity .
Cat. No.: HY-P2612A
Target:
Cat. No.: HY-KM0010
MCE Centrifugal Protein Desalting Column (5 kDa) is a prepacked desalting device containing resin particles with a particle size of 57–80 μm. It efficiently separates small molecules with molecular weights ≤ 5 kDa (such as salts and buffer components) from macromolecules ≥ 5 kDa (such as proteins and peptides), making it suitable for protein desalting and buffer exchange applications.
Cat. No.: HY-LD005
1.2 billion compounds
Cyclic peptide library have advantages such as high affinity, high selectivity, and suitability for targeting protein–protein interactions. Through DEL synthesis technology, the library size can achieve hundreds of millions. DEL cyclic peptide library have advantages like low cost andhigh screeing efficiency, making them valuable for discovering lead compounds against challenging drug targets.
This cyclic peptide library is constructed with unnatural amino acids as building block, synthesized through DNA-compatible chemical reactions. Each cyclic peptide consist of six amino acids and constrained conformations such as side-chain cross-linking, disulfide bonds, and macrocyclization. These cyclic peptides exhibit significantly improved stability and druggability compared with linear peptides, filling the gap between small molecules and macromolecular biologics. Each cyclic peptide is uniquely conjugated to a DNA barcode sequence for molecular identification and sequencing decoding.
MCE’s cyclic peptide library has8 independent sub-libraries, with a total molecular diversity of 1.2 billion. It is constructed via multi-round combinatorial assembly of building blocks and diverse cyclization strategies, facilitating the discovery of cyclic peptide leads for undruggable targets.
Cat. No.: HY-P2973A
Synonyms: Aspergillus acid protease (Xeno-free)
Target:
Research Areas:
Aspergillopepsin I (Xeno-free) is an acid protease and aspartic protease. Aspergillopepsin I (Xeno-free) is derived from the marine fungus Aspergillus tubingensis. Aspergillopepsin I from Aspergillus tubingensis hydrolyzes glycinin, especially the 7S globulin .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
