5 Results for "

stimulant laxative

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "stimulant laxative" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-B0557
CAS No.: 603-50-9
Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect .
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Cat. No.: HY-B2134
CAS No.: 8024-48-4
Casanthranol is a naturally derived, orally active mixture of anthraquinone glycosides that exhibits inhibitory activity against α-synuclein and bioactivities related to laxation . Casanthranol inhibits seed-induced α-synuclein fibrillation in cell-free systems and rescues preformed fibril-induced cytotoxicity in differentiated N2a cells. Casanthranol promotes intestinal transit in both the small and large intestines of mice with experimental constipation. Casanthranol can be used in research related to constipation .
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Cat. No.: HY-N12281
CAS No.: 517-43-1
Sennoside is an orally active apoptosis inducer and stimulant laxative, found in Senna (Cassia angustifolia). Sennoside induces overexpression of wild-type p53 and p21/WAF as part of pathways mediating colonic epithelial cell apoptosis. Sennoside stimulates colonic peristalsis, reverses net water, sodium, chloride absorption to secretion and enhances potassium and calcium secretion. Sennoside increases paracellular permeability to small molecules, accelerates colon transit and softens fecal pellets. Sennoside can be used for the research of constipation, melanosis coli, and colorectal cancer .
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Cat. No.: HY-117749
CAS No.: 14008-48-1
Synonyms: WY 8138; DB09219 acetate
Bisoxatin (WY 8138; DB09219) acetate is a laxative agent. Bisoxatin acetate is a stimulant for intestinal peristalsis and has the potential for the research of constipation disorder .
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Cat. No.: HY-B0557R
CAS No.: 603-50-9
Bisacodyl (Standard) is the analytical standard of Bisacodyl. This product is intended for research and analytical applications. Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect .
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