1. Protein Tyrosine Kinase/RTK Metabolic Enzyme/Protease
  2. SHP2 Phosphatase
  3. SHP2 inhibitor LY6

SHP2 inhibitor LY6 (LY6) is potent and selective inhibitor of SHP2, with an IC50 of 9.8 µM. SHP2 inhibitor LY6 can inhibits SHP2-mediated cell signaling and proliferation.

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SHP2 inhibitor LY6 Chemical Structure

SHP2 inhibitor LY6 Chemical Structure

CAS No. : 2296718-09-5

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Description

SHP2 inhibitor LY6 (LY6) is potent and selective inhibitor of SHP2, with an IC50 of 9.8 µM. SHP2 inhibitor LY6 can inhibits SHP2-mediated cell signaling and proliferation[1].

IC50 & Target

IC50: 9.8 µM (SHP2)[1]

Molecular Weight

564.46

Formula

C30H27Cl2N3O4

CAS No.
SMILES

O=C1N(C2=CCCN(CC3=CC(C(/C=C/C4=CC=C(Cl)C=C4Cl)=O)=C(O)C=C3OCC)C2)C5=CC=CC=C5N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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SHP2 inhibitor LY6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SHP2 inhibitor LY6
Cat. No.:
HY-125257
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