Sodium stearyl fumarate
Based on 1 Customer Validation
Sodium stearyl fumarate (Sodium 2-octadecylfumarate) is a tablet lubricant. Sodium stearyl fumarate reduces die wall friction, sticking, and picking during tableting. Sodium stearyl fumarate exerts a taste-masking effect. Sodium stearyl fumarate better promotes drug dissolution.
For research use only. We do not sell to patients.
- Purity: 99.73%
- CAS No.: 4070-80-8
- Formula: C22H39NaO4
- Molecular Weight:390.53
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Sodium stearyl fumarate (1-3% (w/w); 5 min) improves the compressibility of directly compressed lactose tablets, and provides lubricity and anti-adhesion properties for directly compressed lactose tablets[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4070-80-8
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Appearance Solid
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Molecular Weight 390.53
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Formula C22H39NaO4
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Color White to light yellow
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SMILES
CCCCCCCCCCCCCCCCCCOC(/C=C/C(O[Na])=O)=O
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Synonyms
Sodium 2-octadecylfumarate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
Methanol : 5 mg/mL (12.80 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. van der Meer JW, et al. Abstract!. The Netherlands journal of medicine. 2002 Dec;60(11):418. [Content Brief]
[2]. Mahrous GM, et al. Application of a quality-by-design approach for utilizing sodium stearyl fumarate as a taste-masking agent in dextromethorphan hydrobromide orally disintegrating tablets. Pharmaceutical development and technology. 2019 Jul;24(6):711-719. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol | 1 mM | 2.5606 mL | 12.8031 mL | 25.6062 mL | 64.0156 mL |
| 5 mM | 0.5121 mL | 2.5606 mL | 5.1212 mL | 12.8031 mL | |
| 10 mM | 0.2561 mL | 1.2803 mL | 2.5606 mL | 6.4016 mL |
Sodium stearyl fumarate Related Classifications
HY-W099558 Related Classifications
Powered by Bioz
- Sodium stearyl
- 4070-80-8
- Sodium 2-octadecylfumarate
- Biochemical Assay Reagents
- dextromethorphan hydrobromide
- tablet bonding mechanisms
- Pharmaburst? 500
- salicylic acid granulated tablets
- glyceryl behenate
- lactose direct compression tablets
- magnesium stearate
- dissolution rates
- die wall friction
- orally disintegrating tablets
- Inhibitor
- inhibitor
- inhibit