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Cat. No.: HY-179660

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STING agonist-49-PAB-Ala-Val-CO-C2-mal

STING agonist-49-PAB-Ala-Val-CO-C2-mal, a pep-cSTING linker-payload, is a drug-linker conjugate for ADC. STING agonist-49-PAB-Ala-Val-CO-C2-mal can be used for ADC synthesis.

For research use only. We do not sell to patients.

CAS No.: 2803608-03-7
Formula: C₆₂H₇₃N₁₇O₁₃
Molecular Weight:1264.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

STING agonist-49-PAB-Ala-Val-CO-C2-mal Chemical Structure

CAS No.: 2803608-03-7

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Biological Activity

Description

STING agonist-49-PAB-Ala-Val-CO-C2-mal, a pep-cSTING linker-payload, is a drug-linker conjugate for ADC. STING agonist-49-PAB-Ala-Val-CO-C2-mal can be used for ADC synthesis^[1].

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

CAS No. 2803608-03-7
Molecular Weight 1264.35
Formula C₆₂H₇₃N₁₇O₁₃
SMILES

O=C([C@H](C)NC([C@H](C(C)C)NC(CCN1C(C=CC1=O)=O)=O)=O)NC2=CC=C(COC(N(C)CCCOC3=CC(C(N)=O)=CC4=C3N(C(NC(C5=CC(C)=NN5CC)=O)=N4)C/C=C/CN6C(NC(C7=CC(C)=NN7CC)=O)=NC8=CC(C(N)=O)=CC(OC)=C86)=O)C=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gruber DR, et al. Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models. Mol Cancer Ther. 2025 Oct 29. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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STING agonist-49-PAB-Ala-Val-CO-C2-mal

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STING agonist-49-PAB-Ala-Val-CO-C2-mal

All Drug-Linker Conjugates for ADC Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

STING agonist-49-PAB-Ala-Val-CO-C2-mal Related Classifications

HY-179660 Related Classifications

Bioz

Keywords

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