Sulfo-Cy5-TCO
Sulfo-Cy5-TCO is a water-soluble sulfonated Cy5 fluorescent reagent containing trans-cyclooctene (TCO). Sulfo-Cy5-TCO undergoes an inverse electron demand Diels‑Alder reaction with tetrazine-labeled fixed breast cancer cells to achieve cell labeling. Sulfo-Cy5-TCO is used for fluorescent labeling and imaging of biological samples such as proteins and cells.
For research use only. We do not sell to patients.
- CAS No.: 2129525-69-3
- Formula: C46H62N4O12S3
- Molecular Weight:959.20
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Sulfo-Cy5-TCO undergoes an iEDDA reaction with tetrazine-modified BSA in ammonium acetate buffer at 25 °C to form a fluorescent conjugate, with a yield of approximately 50%[1].
Sulfo-Cy5-TCO can specifically label immobilized MCF7 breast cancer cells with tetrazine tags via the iEDDA reaction, generating detectable red fluorescence, and no non-specific binding is observed under control conditions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
670
633
Chemical Information
-
CAS No. 2129525-69-3
-
Molecular Weight 959.20
-
Formula C46H62N4O12S3
-
SMILES
O=C(NCCCNC(CCCCCN1C2=CC=C(S(=O)(O)=O)C=C2C(C)(C)/C1=C\C=C\C=C\C3=[N+](CCCS(=O)([O-])=O)C4=C(C3(C)C)C=C(S(=O)(O)=O)C=C4)=O)OC5CC/C=C\CCC5
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sulfo-Cy5-TCO Related Classifications
HY-151759 Related Classifications
Powered by Bioz