Taurohyocholic acid
Based on 1 Customer Validation
Taurohyocholic acid is a taurine-conjugated hyocholic acid. Taurohyocholic acid is predictor of the efficacy of tyrosine kinase inhibitors combined withPD-1 inhibitors in hepatocellular carcinoma (HCC).
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 32747-07-2
- Formula: C26H45NO7S
- Molecular Weight:515.70
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Chemical Information
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CAS No. 32747-07-2
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Appearance Solid
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Molecular Weight 515.70
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Formula C26H45NO7S
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Color White to off-white
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SMILES
O[C@@H]1CC[C@]2([C@@]([H])(C1)[C@H]([C@H]([C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@@]4([C@@H](CCC(NCCS(O)(=O)=O)=O)C)[H])[H])C)[H])[H])O)O)C
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Synonyms
THCA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (193.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. He J, et al. Semi-Preparative Isolation and Purification of Three Tauro-Conjugated Cholic Acids from Pulvis Fellis Suis by HSCCC Coupled with ELSD Detection. Chromatographia. 2011;73(3-4):361-365. [Content Brief]
[2]. Chen Y, et al. Taurohyocholic acid acts as a potential predictor of the efficacy of tyrosine kinase inhibitors combined with programmed cell death-1 inhibitors in hepatocellular carcinoma. Front Pharmacol. 2024 Feb 23;15:1364924. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9391 mL | 9.6956 mL | 19.3911 mL | 48.4778 mL |
| 5 mM | 0.3878 mL | 1.9391 mL | 3.8782 mL | 9.6956 mL | |
| 10 mM | 0.1939 mL | 0.9696 mL | 1.9391 mL | 4.8478 mL | |
| 15 mM | 0.1293 mL | 0.6464 mL | 1.2927 mL | 3.2319 mL | |
| 20 mM | 0.0970 mL | 0.4848 mL | 0.9696 mL | 2.4239 mL | |
| 25 mM | 0.0776 mL | 0.3878 mL | 0.7756 mL | 1.9391 mL | |
| 30 mM | 0.0646 mL | 0.3232 mL | 0.6464 mL | 1.6159 mL | |
| 40 mM | 0.0485 mL | 0.2424 mL | 0.4848 mL | 1.2119 mL | |
| 50 mM | 0.0388 mL | 0.1939 mL | 0.3878 mL | 0.9696 mL | |
| 60 mM | 0.0323 mL | 0.1616 mL | 0.3232 mL | 0.8080 mL | |
| 80 mM | 0.0242 mL | 0.1212 mL | 0.2424 mL | 0.6060 mL | |
| 100 mM | 0.0194 mL | 0.0970 mL | 0.1939 mL | 0.4848 mL |