tert-Butyl 2,8-diazaspiro[4.5]decane-2-carboxylate
Based on 1 Customer Validation
tert-Butyl 2,8-diazaspiro[4.5]decane-2-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.82%
- CAS No.: 336191-17-4
- Formula: C13H24N2O2
- Molecular Weight:240.35
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
![tert-Butyl 2,8-diazaspiro[4.5]decane-2-carboxylate Chemical Structure](https://file.medchemexpress.com/product_pic/hy-30605.gif "Click to View tert-Butyl 2,8-diazaspiro[4.5]decane-2-carboxylate Chemical Structure")
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E927 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 336191-17-4
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Appearance Solid-Liquid Mixture
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Molecular Weight 240.35
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Formula C13H24N2O2
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Color Colorless to off-white
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SMILES
O=C(OC(C)(C)C)N1CCC2(C1)CCNCC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 70 mg/mL (291.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1606 mL | 20.8030 mL | 41.6060 mL | 104.0150 mL |
| 5 mM | 0.8321 mL | 4.1606 mL | 8.3212 mL | 20.8030 mL | |
| 10 mM | 0.4161 mL | 2.0803 mL | 4.1606 mL | 10.4015 mL | |
| 15 mM | 0.2774 mL | 1.3869 mL | 2.7737 mL | 6.9343 mL | |
| 20 mM | 0.2080 mL | 1.0401 mL | 2.0803 mL | 5.2007 mL | |
| 25 mM | 0.1664 mL | 0.8321 mL | 1.6642 mL | 4.1606 mL | |
| 30 mM | 0.1387 mL | 0.6934 mL | 1.3869 mL | 3.4672 mL | |
| 40 mM | 0.1040 mL | 0.5201 mL | 1.0401 mL | 2.6004 mL | |
| 50 mM | 0.0832 mL | 0.4161 mL | 0.8321 mL | 2.0803 mL | |
| 60 mM | 0.0693 mL | 0.3467 mL | 0.6934 mL | 1.7336 mL | |
| 80 mM | 0.0520 mL | 0.2600 mL | 0.5201 mL | 1.3002 mL | |
| 100 mM | 0.0416 mL | 0.2080 mL | 0.4161 mL | 1.0401 mL |
tert-Butyl 2,8-diazaspiro[4.5]decane-2-carboxylate Related Classifications
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