tert-Butyl (7-bromoheptyl)carbamate
Based on 1 Customer Validation
tert-Butyl (7-bromoheptyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥95.0%
- CAS No.: 142356-34-1
- Formula: C12H24BrNO2
- Molecular Weight:294.23
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E885 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 142356-34-1
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Appearance Solid
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Molecular Weight 294.23
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Formula C12H24BrNO2
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Color White to off-white
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SMILES
O=C(OC(C)(C)C)NCCCCCCCBr
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (339.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (238 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3987 mL | 16.9935 mL | 33.9870 mL | 84.9675 mL |
| 5 mM | 0.6797 mL | 3.3987 mL | 6.7974 mL | 16.9935 mL | |
| 10 mM | 0.3399 mL | 1.6994 mL | 3.3987 mL | 8.4968 mL | |
| 15 mM | 0.2266 mL | 1.1329 mL | 2.2658 mL | 5.6645 mL | |
| 20 mM | 0.1699 mL | 0.8497 mL | 1.6994 mL | 4.2484 mL | |
| 25 mM | 0.1359 mL | 0.6797 mL | 1.3595 mL | 3.3987 mL | |
| 30 mM | 0.1133 mL | 0.5665 mL | 1.1329 mL | 2.8323 mL | |
| 40 mM | 0.0850 mL | 0.4248 mL | 0.8497 mL | 2.1242 mL | |
| 50 mM | 0.0680 mL | 0.3399 mL | 0.6797 mL | 1.6994 mL | |
| 60 mM | 0.0566 mL | 0.2832 mL | 0.5665 mL | 1.4161 mL | |
| 80 mM | 0.0425 mL | 0.2124 mL | 0.4248 mL | 1.0621 mL | |
| 100 mM | 0.0340 mL | 0.1699 mL | 0.3399 mL | 0.8497 mL |
tert-Butyl (7-bromoheptyl)carbamate Related Classifications
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