tert-Butyl (8-bromooctyl)carbamate
Based on 1 Customer Validation
tert-Butyl (8-bromooctyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥95.0%
- CAS No.: 142356-35-2
- Formula: C13H26BrNO2
- Molecular Weight:308.26
-
Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
-
Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E889 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 142356-35-2
-
Appearance Liquid
-
Molecular Weight 308.26
-
Formula C13H26BrNO2
-
Color Colorless to light yellow
-
SMILES
O=C(OC(C)(C)C)NCCCCCCCCBr
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (324.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (238 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2440 mL | 16.2201 mL | 32.4401 mL | 81.1004 mL |
| 5 mM | 0.6488 mL | 3.2440 mL | 6.4880 mL | 16.2201 mL | |
| 10 mM | 0.3244 mL | 1.6220 mL | 3.2440 mL | 8.1100 mL | |
| 15 mM | 0.2163 mL | 1.0813 mL | 2.1627 mL | 5.4067 mL | |
| 20 mM | 0.1622 mL | 0.8110 mL | 1.6220 mL | 4.0550 mL | |
| 25 mM | 0.1298 mL | 0.6488 mL | 1.2976 mL | 3.2440 mL | |
| 30 mM | 0.1081 mL | 0.5407 mL | 1.0813 mL | 2.7033 mL | |
| 40 mM | 0.0811 mL | 0.4055 mL | 0.8110 mL | 2.0275 mL | |
| 50 mM | 0.0649 mL | 0.3244 mL | 0.6488 mL | 1.6220 mL | |
| 60 mM | 0.0541 mL | 0.2703 mL | 0.5407 mL | 1.3517 mL | |
| 80 mM | 0.0406 mL | 0.2028 mL | 0.4055 mL | 1.0138 mL | |
| 100 mM | 0.0324 mL | 0.1622 mL | 0.3244 mL | 0.8110 mL |
tert-Butyl (8-bromooctyl)carbamate Related Classifications
HY-23016 Related Classifications
Powered by Bioz